Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50017677
TargetSerine-protein kinase ATM(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM245474(US9428503, 1)
Affinity DataIC50: 0.580nMAssay Description:Competitive inhibition of ATM (unknown origin) measured by ATP-competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50565800(Azd-1390 | Azd1390 | US20240294545, Compound AZD13...)
Affinity DataIC50: 0.780nMAssay Description:Competitive inhibition of ATM (unknown origin) measured by ATP-competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50459007(CHEMBL4218734)
Affinity DataIC50: 46nMAssay Description:Competitive inhibition of ATM (unknown origin) measured by ATP-competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50059640(CHEMBL2140173)
Affinity DataIC50: 60nMAssay Description:Competitive inhibition of ATM (unknown origin) measured by ATP-competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50208517(KU-55933 | 2-morpholin-4-yl-6-thianthren-1-yl-pyra...)
Affinity DataIC50: 250nMAssay Description:Competitive inhibition of ATM (unknown origin) measured by ATP-competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine-protein kinase ATM(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50604005(CHEMBL5178407)
Affinity DataIC50: 310nMAssay Description:Competitive inhibition of ATM (unknown origin) measured by ATP-competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50145038(CHEMBL2143829)
Affinity DataIC50: 370nMAssay Description:Competitive inhibition of ATM (unknown origin) measured by ATP-competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50604006(CHEMBL2094953 | DNDI1417761)
Affinity DataIC50: 3.34E+4nMAssay Description:Inhibition of ATM in human MCF7 cells assessed as decrease in pKAP-1 level measured by In-cell western assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed