Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50016053
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591770(CHEMBL5179804)
Affinity DataEC50:  170nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591794(CHEMBL5191977)
Affinity DataEC50:  9.72E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591793(CHEMBL5186398)
Affinity DataEC50:  90nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591792(CHEMBL5201236)
Affinity DataEC50:  90nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591791(CHEMBL5185818)
Affinity DataEC50:  90nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591790(CHEMBL5171832)
Affinity DataEC50:  90nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591789(CHEMBL5208477)
Affinity DataEC50:  120nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591788(CHEMBL5174139)
Affinity DataEC50:  120nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591787(CHEMBL5198713)
Affinity DataEC50:  120nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591786(CHEMBL5207696)
Affinity DataEC50:  120nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591785(CHEMBL5176647)
Affinity DataEC50:  120nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591784(CHEMBL5196120)
Affinity DataEC50:  120nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591783(CHEMBL5177258)
Affinity DataEC50:  120nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591782(CHEMBL5181100)
Affinity DataEC50:  120nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591780(CHEMBL5171038)
Affinity DataEC50:  120nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591769(CHEMBL5200407)
Affinity DataEC50:  170nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591771(CHEMBL5195163)
Affinity DataEC50:  170nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591772(CHEMBL5207605)
Affinity DataEC50:  1.59E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591773(CHEMBL5182080)
Affinity DataEC50:  170nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50292579(Peucedanone | CHEMBL459826)
Affinity DataEC50:  170nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591774(CHEMBL5203645)
Affinity DataEC50:  170nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591776(CHEMBL5181220)
Affinity DataEC50:  170nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591777(CHEMBL5196422)
Affinity DataEC50:  1.87E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591778(CHEMBL5176175)
Affinity DataEC50:  170nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591779(CHEMBL5191516)
Affinity DataEC50:  170nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591781(CHEMBL5203954)
Affinity DataEC50:  120nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591775(CHEMBL5189977)
Affinity DataEC50:  170nMAssay Description:Inhibition of HIV-1 reverse transcriptase in virus infected human C8166 cells assessed as reduction in virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591802(CHEMBL5187675)
Affinity DataIC50: 1nMAssay Description:Inhibition of HIV-1 reverse transcriptase preincubated for 45 mins followed by substrate addition by immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591798(CHEMBL3342990)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of wild-type HIV-1 reverse transcriptase by Picogreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591800(CHEMBL5191400)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of HIV-1 reverse transcriptase using ABTS as substrate and RNA template primed with oligo(dT)12-18 in presence of digoxigenin/biotin-label...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591803(CHEMBL5197402)
Affinity DataIC50: 10nMAssay Description:Inhibition of HIV-1 LTR reverse transcriptase infected in human CEM cells using RNA template incubated for 1 hr by RT-PCR based cell-free assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591804(CHEMBL5199273)
Affinity DataIC50: 50nMAssay Description:Inhibition of HIV-1 LTR reverse transcriptase infected in human CEM cells using RNA template incubated for 1 hr by RT-PCR based cell-free assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591801(CHEMBL5207632)
Affinity DataIC50: 300nMAssay Description:Inhibition of HIV-1 reverse transcriptase preincubated for 45 mins followed by substrate addition by immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591799(CHEMBL5188770)
Affinity DataIC50: 720nMAssay Description:Inhibition of HIV-1 reverse transcriptase using ABTS as substrate and RNA template primed with oligo(dT)12-18 in presence of digoxigenin/biotin-label...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591805(CHEMBL5198501)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of HIV-1 LTR reverse transcriptase infected in human CEM cells using RNA template incubated for 1 hr by RT-PCR based cell-free assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591796(CHEMBL5189624)
Affinity DataIC50: 4.65E+3nMAssay Description:Inhibition of recombinant HIV-1 subtype C integrase using double-stranded FITC-labelled target DNA as substrate pre-incubated for 45 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591797(CHEBI:2822 | CHEMBL505516)
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of recombinant HIV-1 subtype C integrase using double-stranded FITC-labelled target DNA as substrate pre-incubated for 45 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM22984(Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...)
Affinity DataIC50: 7.41E+4nMAssay Description:Inhibition of recombinant HIV-1 reverse transcriptase using ABTS as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50591795(CHEBI:36124 | (-)-Quinic Acid | CHEMBL444501)
Affinity DataIC50: 2.79E+5nMAssay Description:Inhibition of recombinant HIV-1 reverse transcriptase using ABTS as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed