Compile Data Set for Download or QSAR
Report error Found 47 Enz. Inhib. hit(s) with all data for entry = 50016452
TargetAcetylcholinesterase(Electric eel)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50595061(CHEMBL5209357)
Affinity DataIC50: 0.25nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine chloride as substrate preincubated for 20 mins followed by substrate addition by DTNB reagent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50595058(CHEMBL5199704)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of recombinant human AChE using Amplex red, acetylthiocholine as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50595064(CHEMBL582490 | GNF-Pf-3382)
Affinity DataIC50: 14nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50595063(DIHYDROACTINIDIOLIDE)
Affinity DataIC50: 30nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate preincubated for 45 mins followed by substrate addition by DTNB reage...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50553263(CHEMBL4790416)
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human AChE using Amplex red, acetylthiocholine as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50595055(CHEMBL5200462)
Affinity DataIC50: 35nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50539579(CHEMBL4644113)
Affinity DataIC50: 120nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetBeta-secretase 1(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50595062(CHEMBL5196827)
Affinity DataIC50: 129nMAssay Description:Inhibition of human BACE-1 using Rh-EVNLDAEFK-quencher as peptide substrate incubated for 1 hr in dark by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50595052(CHEMBL5177450)
Affinity DataIC50: 150nMAssay Description:Inhibition of Electrophorus electricus AchE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition by El...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCholinesterase(Horse)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50595064(CHEMBL582490 | GNF-Pf-3382)
Affinity DataIC50: 182nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50595057(CHEMBL5202551)
Affinity DataIC50: 240nMAssay Description:Inhibition of NMDA receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50595067(CHEMBL5208806)
Affinity DataIC50: 390nMAssay Description:Inhibition of Electrophorus electricus AchE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50504429(CHEMBL4455506)
Affinity DataIC50: 440nMAssay Description:Inhibition of Electrophorus electricus AchE using acetylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM24724((adamantan-1-ylmethyl)({3-[(7-chloroquinolin-4-yl)...)
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCholinesterase(Horse)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50595056(CHEMBL5197661)
Affinity DataIC50: 615nMAssay Description:Inhibition of horse serum BuChE using butyrylthiocholine chloride as substrate by spectrophotometric based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCholinesterase(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50553263(CHEMBL4790416)
Affinity DataIC50: 660nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate preincubated for 30 mins followed by substrate addition and measured after 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50595067(CHEMBL5208806)
Affinity DataIC50: 830nMAssay Description:Inhibition of FAAH (unknown origin) using 7-amino-4-methylcoumarin-arachidonamide as substrate preincubated for 5 mins followed by substrate addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50504429(CHEMBL4455506)
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of recombinant human MAO-B assessed as formation of 4-hydroxyquinoline using kynuramine as a substrate incubated for 30 mins by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50595051(CHEMBL5191506)
Affinity DataIC50: 2.63E+3nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetBeta-secretase 1(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50595066(CHEMBL5188397)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant human BACE-1 using MCA-SEVNLDAEFR-Ednp-KRR-NH2.3TFA as substrate incubated for 2 hrs by Varioskan-flash multimode plate rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50595062(CHEMBL5196827)
Affinity DataIC50: 3.29E+3nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate preincubated for 6 mins followed by substrate addition and measured for 12 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCholinesterase(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50595053(CHEMBL5182966)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of BuChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCholinesterase(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50595051(CHEMBL5191506)
Affinity DataIC50: 3.76E+3nMAssay Description:Inhibition of recombinant human BuChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50595054(CHEMBL5202021)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM225274(2-[4-(4-Ethylpiperazin-1-yl)phenyl]-1H-benzo[d]imi...)
Affinity DataIC50: 5.18E+3nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50590392(CHEMBL5170410)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of recombinant human MAO-A assessed as amount of 4-hydroxyquinoline using kynuramine as a substrate incubated for 30 mins by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetBeta-secretase 1(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50595054(CHEMBL5202021)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of human BACE-1 using rhodamine-EVNLDAEFK-quencher as peptide substrate incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50595056(CHEMBL5197661)
Affinity DataIC50: 6.77E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate by spectrophotometric based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50595065(CHEMBL5208803)
Affinity DataIC50: 8.07E+3nMAssay Description:Inhibition of self induced amyloid beta (1 to 42) (unknown origin) aggregation incubated for 24 hrs by Thioflavin T based fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50590392(CHEMBL5170410)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of recombinant human MAO-B assessed as amount of 4-hydroxyquinoline using kynuramine as a substrate incubated for 30 mins by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCholinesterase(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50590392(CHEMBL5170410)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of BuChE (unknown origin) incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50595062(CHEMBL5196827)
Affinity DataIC50: 9.26E+3nMAssay Description:Inhibition of amyloid beta (1 to 42) (unknown origin) self aggregation incubated for 24 hrs by Thioflavin T based fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50553263(CHEMBL4790416)
Affinity DataIC50: 9.91E+3nMAssay Description:Inhibition of recombinant human MAO-B using p-tyramine as substrate preincubated for 15 mins followed by substrate addition and measured after 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50595060(CHEMBL449947 | CHEBI:17527)
Affinity DataIC50: 1.19E+4nMAssay Description:Inhibition of AChE (unknown origin) by spectrophotometric based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50590392(CHEMBL5170410)
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of Electrophorus electricus AchE incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50413824(CHEMBL473093)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of Electrophorus electricus AchE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCholinesterase(Horse)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50413824(CHEMBL473093)
Affinity DataIC50: 1.46E+4nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50595059(CHEMBL5191152)
Affinity DataIC50: 1.47E+4nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCholinesterase(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50595060(CHEMBL449947 | CHEBI:17527)
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of BuChE (unknown origin) by spectrophotometric based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50553263(CHEMBL4790416)
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of recombinant human MAO-A using p-tyramine as substrate preincubated for 15 mins followed by substrate addition and measured after 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetBeta-secretase 1(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50269544(tellimagrandin II | CHEMBL510512)
Affinity DataIC50: 2.02E+4nMAssay Description:Inhibition of BACE-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50595054(CHEMBL5202021)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human LOX-5 using arachidonic acid and ATP as substrate preincubated for 10 mins followed by substrate addition and measured after 20 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCholinesterase(Horse)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM225274(2-[4-(4-Ethylpiperazin-1-yl)phenyl]-1H-benzo[d]imi...)
Affinity DataIC50: 3.49E+4nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50595061(CHEMBL5209357)
Affinity DataIC50: 4.91E+4nMAssay Description:Inhibition of amyloid beta (1 to 42) (unknown origin) self aggregation incubated for 24 hrs by Thioflavin T based fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50595055(CHEMBL5200462)
Affinity DataIC50: 3.38E+5nMAssay Description:Inhibition of self-induced amyloid beta (1 to 42) (unknown origin) aggregation by Thioflavin T based fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50595055(CHEMBL5200462)
Affinity DataIC50: 4.41E+5nMAssay Description:Inhibition of MMP-2 (unknown origin) by Fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCholinesterase(Horse)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50595061(CHEMBL5209357)
Affinity DataIC50: 3.30E+6nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine chloride as substrate preincubated for 20 mins followed by substrate addition by DTNB reage...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed