Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 50016061
TargetSerine/threonine-protein kinase Chk1(Human)
Csir-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50185219((S)-3-(1H-benzo[d]imidazol-2-yl)-6-chloro-4-(quinu...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of Chk1 (unknown origin) expressed in Sf9 insect cells using biotinylated cdc25c peptide as substrate in presence of 33P-gamma-labeled ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA topoisomerase 1(Human)
Csir-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50510239(CHEMBL4454135)
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant human Top1 derived from human MCF7 cell extract incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA topoisomerase 1(Human)
Csir-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50510249(CHEMBL4463318)
Affinity DataIC50: 1.79E+3nMAssay Description:Inhibition of recombinant human Top1 derived from human MCF7 cell extract incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed