Compile Data Set for Download or QSAR
Report error Found 79 Enz. Inhib. hit(s) with all data for entry = 50017834
TargetAdvanced glycosylation end product-specific receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50249581(CHEBI:6700 | Matrine)
Affinity DataKd:  2.39E+7nMAssay Description:Binding affinity to human RAGE by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdvanced glycosylation end product-specific receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50249580(Azeliragon | PF-04494700 | TTP448 | US11524942, Co...)
Affinity DataKd:  13nMAssay Description:Binding affinity to recombinant human RAGE assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50151982(5-{4-[4-(5-Cyano-1H-indol-3-yl)-butyl]-piperazin-1...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of SERT (unknown origin) expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent serotonin transporter(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605302(CHEMBL5191418)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of SERT (unknown origin) expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605305(CHEMBL5176363)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of SERT (unknown origin) expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605288(CHEMBL5180472)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of SERT (unknown origin) expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605304(CHEMBL5181226)
Affinity DataIC50: 5nMAssay Description:Inhibition of SERT (unknown origin) expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605306(CHEMBL5184959)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of SERT (unknown origin) expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605287(CHEMBL5170075)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of SERT (unknown origin) expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605307(CHEMBL5175011)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of SERT (unknown origin) expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605303(CHEMBL5208902)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of SERT (unknown origin) expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605290(CHEMBL5183093)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of SERT (unknown origin) expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605289(CHEMBL5201565)
Affinity DataIC50: 11nMAssay Description:Inhibition of SERT (unknown origin) expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605285(CHEMBL5207117)
Affinity DataIC50: 12nMAssay Description:Inhibition of SERT (unknown origin) expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605309(CHEMBL5183581)
Affinity DataIC50: 14nMAssay Description:Inhibition of SERT (unknown origin) expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605308(CHEMBL5170676)
Affinity DataIC50: 14nMAssay Description:Inhibition of SERT (unknown origin) expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605313(CHEMBL5180815)
Affinity DataIC50: 15nMAssay Description:Inhibition of SERT (unknown origin) expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605312(CHEMBL5173093)
Affinity DataIC50: 19nMAssay Description:Inhibition of SERT (unknown origin) expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605294(CHEMBL5203206)
Affinity DataIC50: 31nMAssay Description:Inhibition of SERT (unknown origin) expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605314(CHEMBL5200156)
Affinity DataIC50: 42nMAssay Description:Inhibition of SERT (unknown origin) expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605315(CHEMBL5204395)
Affinity DataIC50: 46nMAssay Description:Inhibition of SERT (unknown origin) expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605310(CHEMBL5194592)
Affinity DataIC50: 58nMAssay Description:Inhibition of SERT (unknown origin) expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605283(CHEMBL5188606)
Affinity DataIC50: 66nMAssay Description:Inhibition of SERT (unknown origin) expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605286(CHEMBL5192104)
Affinity DataIC50: 68nMAssay Description:Inhibition of SERT (unknown origin) expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605291(CHEMBL5170035)
Affinity DataIC50: 100nMAssay Description:Inhibition of SERT (unknown origin) expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605292(CHEMBL5177452)
Affinity DataIC50: 100nMAssay Description:Inhibition of SERT (unknown origin) expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605293(CHEMBL5206806)
Affinity DataIC50: 100nMAssay Description:Inhibition of SERT (unknown origin) expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605300(CHEMBL5204858)
Affinity DataIC50: 100nMAssay Description:Inhibition of SERT (unknown origin) expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605295(CHEMBL5208411)
Affinity DataIC50: 100nMAssay Description:Inhibition of SERT (unknown origin) expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605296(CHEMBL5196372)
Affinity DataIC50: 100nMAssay Description:Inhibition of SERT (unknown origin) expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605297(CHEMBL5172417)
Affinity DataIC50: 100nMAssay Description:Inhibition of SERT (unknown origin) expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605298(CHEMBL5174761)
Affinity DataIC50: 100nMAssay Description:Inhibition of SERT (unknown origin) expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605299(CHEMBL5199141)
Affinity DataIC50: 100nMAssay Description:Inhibition of SERT (unknown origin) expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605301(CHEMBL5178447)
Affinity DataIC50: 100nMAssay Description:Inhibition of SERT (unknown origin) expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605316(CHEMBL5178292)
Affinity DataIC50: 100nMAssay Description:Inhibition of SERT (unknown origin) expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605311(CHEMBL5172714)
Affinity DataIC50: 100nMAssay Description:Inhibition of SERT (unknown origin) expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50249580(Azeliragon | PF-04494700 | TTP448 | US11524942, Co...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of hERG transfected in CHO cells by manual patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605284(CHEMBL5170867)
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of SERT (unknown origin) expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50249580(Azeliragon | PF-04494700 | TTP448 | US11524942, Co...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of SERT (unknown origin) expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdvanced glycosylation end product-specific receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605302(CHEMBL5191418)
Affinity DataIC50: 3.49E+3nMAssay Description:Inhibition of biotinylated human RAGE/amyloid beta interaction incubated for 120 mins by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdvanced glycosylation end product-specific receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605310(CHEMBL5194592)
Affinity DataIC50: 4.04E+3nMAssay Description:Inhibition of biotinylated human RAGE/amyloid beta interaction incubated for 120 mins by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdvanced glycosylation end product-specific receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605284(CHEMBL5170867)
Affinity DataIC50: 4.15E+3nMAssay Description:Inhibition of biotinylated human RAGE/amyloid beta interaction incubated for 120 mins by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50151982(5-{4-[4-(5-Cyano-1H-indol-3-yl)-butyl]-piperazin-1...)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of hERG transfected in CHO cells by manual patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdvanced glycosylation end product-specific receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605313(CHEMBL5180815)
Affinity DataIC50: 6.03E+3nMAssay Description:Inhibition of biotinylated human RAGE/amyloid beta interaction incubated for 120 mins by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605294(CHEMBL5203206)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of hERG transfected in CHO cells by manual patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdvanced glycosylation end product-specific receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605294(CHEMBL5203206)
Affinity DataIC50: 8.26E+3nMAssay Description:Inhibition of biotinylated human RAGE/amyloid beta interaction incubated for 120 mins by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdvanced glycosylation end product-specific receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605307(CHEMBL5175011)
Affinity DataIC50: 8.29E+3nMAssay Description:Inhibition of biotinylated human RAGE/amyloid beta interaction incubated for 120 mins by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdvanced glycosylation end product-specific receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50397836(CHEMBL2179073)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of biotinylated human RAGE/amyloid beta interaction incubated for 120 mins by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdvanced glycosylation end product-specific receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605303(CHEMBL5208902)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of biotinylated human RAGE/amyloid beta interaction incubated for 120 mins by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdvanced glycosylation end product-specific receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50605283(CHEMBL5188606)
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of biotinylated human RAGE/amyloid beta interaction incubated for 120 mins by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
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