Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50017847
TargetPoly [ADP-ribose] polymerase 2(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50084621(BMN 673 | Talazoparib | US12427157, Example R8H-15)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of PARP2 (unknown origin) using NAD as substrate incubated for 1 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 2(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50446130(AG-014699 | AG-14447 | Rucaparib | RUCAPARIB CAMSY...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of PARP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 4(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50605409(CHEMBL5209870)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of BRD4 (unknown origin) incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50084621(BMN 673 | Talazoparib | US12427157, Example R8H-15)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of PARP1 (unknown origin) using NAD as substrate incubated for 1 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50446130(AG-014699 | AG-14447 | Rucaparib | RUCAPARIB CAMSY...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50605409(CHEMBL5209870)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of PARP1 (unknown origin) using NAD+ as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50: 8nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 4(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50210164(CHEMBL2132936)
Affinity DataIC50: 68nMAssay Description:Inhibition of BRD4 BD2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50210164(CHEMBL2132936)
Affinity DataIC50: 103nMAssay Description:Inhibition of BRD4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50210164(CHEMBL2132936)
Affinity DataIC50: 118nMAssay Description:Inhibition of BRD4 BD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50605410(CHEMBL5197463)
Affinity DataIC50: 175nMAssay Description:Inhibition of BRD4 BD2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50605410(CHEMBL5197463)
Affinity DataIC50: 197nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50605410(CHEMBL5197463)
Affinity DataIC50: 238nMAssay Description:Inhibition of BRD4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50605410(CHEMBL5197463)
Affinity DataIC50: 251nMAssay Description:Inhibition of BRD4 BD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed