Compile Data Set for Download or QSAR
Report error Found 489 Enz. Inhib. hit(s) with all data for entry = 50016734
Target5-hydroxytryptamine receptor 2C(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataEC50:  0.320nMAssay Description:Agonist activity at human 5HT2C receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataEC50:  0.324nMAssay Description:Agonist activity at human 5HT2C receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataEC50:  0.347nMAssay Description:Agonist activity at human 5HT2A receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataEC50:  0.350nMAssay Description:Agonist activity at human 5HT2A receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataEC50:  0.360nMAssay Description:Agonist activity at human 5HT2B receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataEC50:  0.363nMAssay Description:Agonist activity at human 5HT2B receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596945(CHEMBL5207529)
Affinity DataEC50:  0.468nMAssay Description:Agonist activity at human 5HT2C receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596862(CHEMBL5198213)
Affinity DataEC50:  0.490nMAssay Description:Agonist activity at human 5HT2A receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596945(CHEMBL5207529)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at human 5HT2C receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596862(CHEMBL5198213)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at human 5HT2A receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596945(CHEMBL5207529)
Affinity DataEC50:  0.575nMAssay Description:Agonist activity at human 5HT2B receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596945(CHEMBL5207529)
Affinity DataEC50:  0.580nMAssay Description:Agonist activity at human 5HT2B receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596862(CHEMBL5198213)
Affinity DataEC50:  0.794nMAssay Description:Agonist activity at human 5HT2C receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596862(CHEMBL5198213)
Affinity DataEC50:  0.800nMAssay Description:Agonist activity at human 5HT2C receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596937(CHEMBL5204071)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human 5HT2C receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596937(CHEMBL5204071)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human 5HT2C receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596937(CHEMBL5204071)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at human 5HT2B receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596937(CHEMBL5204071)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at human 5HT2B receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596934(CHEMBL5200026)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at human 5HT2A receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596934(CHEMBL5200026)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at human 5HT2A receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596945(CHEMBL5207529)
Affinity DataEC50:  1.70nMAssay Description:Agonist activity at human 5HT2A receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596945(CHEMBL5207529)
Affinity DataEC50:  1.70nMAssay Description:Agonist activity at human 5HT2A receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596934(CHEMBL5200026)
Affinity DataEC50:  1.90nMAssay Description:Agonist activity at human 5HT2C receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596934(CHEMBL5200026)
Affinity DataEC50:  1.90nMAssay Description:Agonist activity at human 5HT2C receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596945(CHEMBL5207529)
Affinity DataKi:  2.5nMAssay Description:Binding affinity to 5HT7 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596945(CHEMBL5207529)
Affinity DataKi:  2.90nMAssay Description:Binding affinity to 5HT2B receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596936(CHEMBL5170784)
Affinity DataEC50:  3.10nMAssay Description:Agonist activity at human 5HT2B receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596936(CHEMBL5170784)
Affinity DataEC50:  3.20nMAssay Description:Agonist activity at human 5HT2B receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596937(CHEMBL5204071)
Affinity DataEC50:  3.20nMAssay Description:Agonist activity at human 5HT2A receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596937(CHEMBL5204071)
Affinity DataEC50:  3.20nMAssay Description:Agonist activity at human 5HT2A receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596867(CHEMBL5178632)
Affinity DataEC50:  3.80nMAssay Description:Agonist activity at human 5HT2A receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596867(CHEMBL5178632)
Affinity DataEC50:  4nMAssay Description:Agonist activity at human 5HT2A receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596886(CHEMBL5179588)
Affinity DataEC50:  4.30nMAssay Description:Agonist activity at human 5HT2C receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596886(CHEMBL5179588)
Affinity DataEC50:  4.40nMAssay Description:Agonist activity at human 5HT2C receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596937(CHEMBL5204071)
Affinity DataKi:  4.40nMAssay Description:Binding affinity to 5HT2B receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596936(CHEMBL5170784)
Affinity DataKi:  4.5nMAssay Description:Binding affinity to 5HT2B receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596867(CHEMBL5178632)
Affinity DataEC50:  7.60nMAssay Description:Agonist activity at human 5HT2C receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596867(CHEMBL5178632)
Affinity DataEC50:  7.90nMAssay Description:Agonist activity at human 5HT2C receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596936(CHEMBL5170784)
Affinity DataKi:  8nMAssay Description:Binding affinity to 5HT7 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596936(CHEMBL5170784)
Affinity DataEC50:  8.30nMAssay Description:Agonist activity at human 5HT2A receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596936(CHEMBL5170784)
Affinity DataEC50:  8.30nMAssay Description:Agonist activity at human 5HT2A receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596936(CHEMBL5170784)
Affinity DataEC50:  8.90nMAssay Description:Agonist activity at human 5HT2C receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596936(CHEMBL5170784)
Affinity DataEC50:  8.90nMAssay Description:Agonist activity at human 5HT2C receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596899(CHEMBL5199923)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human 5HT2C receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596899(CHEMBL5199923)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human 5HT2C receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596946(CHEMBL5182943)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human 5HT2B receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596946(CHEMBL5182943)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human 5HT2B receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596853(CHEMBL5177900)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human 5HT2C receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596853(CHEMBL5177900)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human 5HT2C receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596879(CHEMBL4790446)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human 5HT2A receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
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