Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50015190
TargetSodium-dependent serotonin transporter(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50583564(CHEMBL5081803)
Affinity DataIC50: 24nMAssay Description:Inhibition of human SERT receptor expressed in human HEK293 cells assessed as inhibition of substrate transport measured after 1 hr by flourescence b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50583561(CHEMBL5078388)
Affinity DataIC50: 31nMAssay Description:Inhibition of human SERT receptor expressed in human HEK293 cells assessed as inhibition of substrate transport measured after 1 hr by flourescence b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50583562(CHEMBL5093316)
Affinity DataIC50: 55nMAssay Description:Inhibition of human SERT receptor expressed in human HEK293 cells assessed as inhibition of substrate transport measured after 1 hr by flourescence b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM213826(Dextromethorphan | US11535596, Compound Dextrometh...)
Affinity DataIC50: 56nMAssay Description:Inhibition of human SERT receptor expressed in human HEK293 cells assessed as inhibition of substrate transport measured after 1 hr by flourescence b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50583563(CHEMBL5086545)
Affinity DataIC50: 60nMAssay Description:Inhibition of human SERT receptor expressed in human HEK293 cells assessed as inhibition of substrate transport measured after 1 hr by flourescence b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50583564(CHEMBL5081803)
Affinity DataIC50: 944nMAssay Description:Inhibition of human NET expressed in human HEK293 cells assessed as inhibition of substrate transport measured after 1 hr by flourescence based plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50583563(CHEMBL5086545)
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of human NET expressed in human HEK293 cells assessed as inhibition of substrate transport measured after 1 hr by flourescence based plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50583562(CHEMBL5093316)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human NET expressed in human HEK293 cells assessed as inhibition of substrate transport measured after 1 hr by flourescence based plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50583561(CHEMBL5078388)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human NET expressed in human HEK293 cells assessed as inhibition of substrate transport measured after 1 hr by flourescence based plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM213826(Dextromethorphan | US11535596, Compound Dextrometh...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human NET expressed in human HEK293 cells assessed as inhibition of substrate transport measured after 1 hr by flourescence based plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM213826(Dextromethorphan | US11535596, Compound Dextrometh...)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]-Citalopram from SERT receptor (unknown origin) expressed in HEK cell membrane incubated for 2 hrs by liquid scintillation counte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50583564(CHEMBL5081803)
Affinity DataKi:  35nMAssay Description:Displacement of [3H]-Citalopram from NET (unknown origin) expressed in HEK cell membrane incubated for 2 hrs by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50583561(CHEMBL5078388)
Affinity DataKi:  48nMAssay Description:Displacement of [3H]-Citalopram from SERT receptor (unknown origin) expressed in HEK cell membrane incubated for 2 hrs by liquid scintillation counte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50583564(CHEMBL5081803)
Affinity DataKi:  51nMAssay Description:Displacement of [3H]-Citalopram from SERT receptor (unknown origin) expressed in HEK cell membrane incubated for 2 hrs by liquid scintillation counte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM213826(Dextromethorphan | US11535596, Compound Dextrometh...)
Affinity DataKi:  73nMAssay Description:Displacement of [3H]-Citalopram from sigma-1 receptor (unknown origin) expressed in HEK cell membrane incubated for 2 hrs by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM224023(Dextrorphan)
Affinity DataKi:  118nMAssay Description:Displacement of [3H]-Citalopram from sigma-1 receptor (unknown origin) expressed in HEK cell membrane incubated for 2 hrs by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50583563(CHEMBL5086545)
Affinity DataKi:  125nMAssay Description:Displacement of [3H]-Citalopram from SERT receptor (unknown origin) expressed in HEK cell membrane incubated for 2 hrs by liquid scintillation counte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50583564(CHEMBL5081803)
Affinity DataKi:  145nMAssay Description:Displacement of [3H]-Citalopram from sigma-1 receptor (unknown origin) expressed in HEK cell membrane incubated for 2 hrs by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50583562(CHEMBL5093316)
Affinity DataKi:  186nMAssay Description:Displacement of [3H]-Citalopram from SERT receptor (unknown origin) expressed in HEK cell membrane incubated for 2 hrs by liquid scintillation counte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50583566(CHEMBL5091124)
Affinity DataKi:  301nMAssay Description:Displacement of [3H]-Citalopram from SERT receptor (unknown origin) expressed in HEK cell membrane incubated for 2 hrs by liquid scintillation counte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM224023(Dextrorphan)
Affinity DataKi: >340nMAssay Description:Displacement of [3H]-Citalopram from NET (unknown origin) expressed in HEK cell membrane incubated for 2 hrs by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50583564(CHEMBL5081803)
Affinity DataKi:  353nMAssay Description:Displacement of [3H]-Citalopram from sigma-2 receptor (unknown origin) expressed in HEK cell membrane incubated for 2 hrs by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM224023(Dextrorphan)
Affinity DataKi:  401nMAssay Description:Displacement of [3H]-Citalopram from SERT receptor (unknown origin) expressed in HEK cell membrane incubated for 2 hrs by liquid scintillation counte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50583562(CHEMBL5093316)
Affinity DataKi:  568nMAssay Description:Displacement of [3H]-Citalopram from sigma-1 receptor (unknown origin) expressed in HEK cell membrane incubated for 2 hrs by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50583566(CHEMBL5091124)
Affinity DataKi:  675nMAssay Description:Displacement of [3H]-Citalopram from sigma-1 receptor (unknown origin) expressed in HEK cell membrane incubated for 2 hrs by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50583561(CHEMBL5078388)
Affinity DataKi:  757nMAssay Description:Displacement of [3H]-Citalopram from sigma-1 receptor (unknown origin) expressed in HEK cell membrane incubated for 2 hrs by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50583563(CHEMBL5086545)
Affinity DataKi:  813nMAssay Description:Displacement of [3H]-Citalopram from sigma-1 receptor (unknown origin) expressed in HEK cell membrane incubated for 2 hrs by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50583566(CHEMBL5091124)
Affinity DataKi:  826nMAssay Description:Displacement of [3H]-Citalopram from sigma-2 receptor (unknown origin) expressed in HEK cell membrane incubated for 2 hrs by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50583561(CHEMBL5078388)
Affinity DataKi:  833nMAssay Description:Displacement of [3H]-Citalopram from sigma-2 receptor (unknown origin) expressed in HEK cell membrane incubated for 2 hrs by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM213826(Dextromethorphan | US11535596, Compound Dextrometh...)
Affinity DataKi:  862nMAssay Description:Displacement of [3H]-Citalopram from sigma-2 receptor (unknown origin) expressed in HEK cell membrane incubated for 2 hrs by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50583563(CHEMBL5086545)
Affinity DataKi:  885nMAssay Description:Displacement of [3H]-Citalopram from sigma-2 receptor (unknown origin) expressed in HEK cell membrane incubated for 2 hrs by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50583562(CHEMBL5093316)
Affinity DataKi:  1.28E+3nMAssay Description:Displacement of [3H]-Citalopram from sigma-2 receptor (unknown origin) expressed in HEK cell membrane incubated for 2 hrs by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50583565(CHEMBL5079863)
Affinity DataKi:  1.40E+3nMAssay Description:Displacement of [3H]-Citalopram from sigma-2 receptor (unknown origin) expressed in HEK cell membrane incubated for 2 hrs by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM224023(Dextrorphan)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-Citalopram from sigma-2 receptor (unknown origin) expressed in HEK cell membrane incubated for 2 hrs by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50583565(CHEMBL5079863)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-Citalopram from SERT receptor (unknown origin) expressed in HEK cell membrane incubated for 2 hrs by liquid scintillation counte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50583565(CHEMBL5079863)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-Citalopram from sigma-1 receptor (unknown origin) expressed in HEK cell membrane incubated for 2 hrs by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50583566(CHEMBL5091124)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-Citalopram from NET (unknown origin) expressed in HEK cell membrane incubated for 2 hrs by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50583565(CHEMBL5079863)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-Citalopram from NET (unknown origin) expressed in HEK cell membrane incubated for 2 hrs by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50583563(CHEMBL5086545)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-Citalopram from NET (unknown origin) expressed in HEK cell membrane incubated for 2 hrs by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50583562(CHEMBL5093316)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-Citalopram from NET (unknown origin) expressed in HEK cell membrane incubated for 2 hrs by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50583561(CHEMBL5078388)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-Citalopram from NET (unknown origin) expressed in HEK cell membrane incubated for 2 hrs by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM213826(Dextromethorphan | US11535596, Compound Dextrometh...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-Citalopram from NET (unknown origin) expressed in HEK cell membrane incubated for 2 hrs by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed