Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50016295
TargetSentrin-specific protease 1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50447758(CHEBI:9287 | NSC-45383 | Nigrin | Rufocromomycin |...)
Affinity DataIC50: 520nMAssay Description:Inhibition of SENP1 (unknown origin) using AMC-tagged SUMO1 as fluorogenic substrate preincubated for 10 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetSentrin-specific protease 1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50593989(CHEBI:70682 | Tomentic Acid | Tormentic Acid | TOM...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of recombinant human SENP1 assessed as reduction in deSUMOylation using RanGAP1-SUMO1 as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetSentrin-specific protease 1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50241553(pomolic acid | CHEMBL486986)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of recombinant human SENP1 assessed as reduction in deSUMOylation using RanGAP1-SUMO1 as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetSentrin-specific protease 1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50591762(CHEMBL470172)
Affinity DataIC50: 1.54E+4nMAssay Description:Inhibition of SENP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed