Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50015893
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandPNGBDBM50503530(CHEMBL4437645)
Affinity DataEC50:  9.10nMAssay Description:Inhibition of CSF-1R (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandPNGBDBM50523050(CHEMBL4455953)
Affinity DataIC50: 0.0500nMAssay Description:Degradation of ER alpha in human MCF7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEstrogen receptor(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandPNGBDBM368199((S)-2-(4-(2-(3-(fluoromethyl)azetidin-1-yl)ethoxy)...)
Affinity DataIC50: 0.100nMAssay Description:Degradation of ER alpha in human MCF7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEstrogen receptor(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandPNGBDBM368197((-)-2-(4-(2-(3-(Fluoromethyl)azetidin-1-yl)ethoxy)...)
Affinity DataIC50: 0.300nMAssay Description:Degradation of ER alpha in human MCF7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandPNGBDBM50523051(CHEMBL4456532)
Affinity DataIC50: 0.420nMAssay Description:Degradation of ER alpha in human MCF7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandPNGBDBM368198((R)-2-(4-(2-(3-(Fluoromethyl)azetidin-1-yl)ethoxy)...)
Affinity DataIC50: 13nMAssay Description:Degradation of ER alpha in human MCF7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetAlpha-L-iduronidase(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandPNGBDBM50590372(CHEMBL5196078)
Affinity DataIC50: 1.22E+4nMAssay Description:Inhibition of human recombinant alpha-L-iduronidase incubated for 60 mins by fluoroscence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetAlpha-L-iduronidase(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandPNGBDBM50590373(CHEMBL5189090)
Affinity DataIC50: 4.06E+4nMAssay Description:Inhibition of human recombinant alpha-L-iduronidase incubated for 60 mins by fluoroscence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed