Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50016924
TargetLysosomal acid glucosylceramidase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50598382(CHEMBL5192083)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human GCase assessed as reduction of 4-methylumbelliferone liberation using 4-methylumbelliferyl-beta-glucopyranoside as substrate incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50598385(CHEMBL5189151)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of human GCaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50598386(CHEMBL3393682)
Affinity DataIC50: 9nMAssay Description:Inhibition of human GCaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50182801(CHEMBL206468 | AFEGOSTAT TARTRATE | D-Isofagomine ...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human GCase assessed as reduction of 4-methylumbelliferone liberation using 4-methylumbelliferyl-beta-glucopyranoside as substrate prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50242628(N-dodecyldeoxynojirimycin | CHEMBL450985)
Affinity DataIC50: 50nMAssay Description:Inhibition of human GCase assessed as reduction of 4-methylumbelliferone liberation using 4-methylumbelliferyl-beta-glucopyranoside as substrate prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50598389(CHEMBL3751947)
Affinity DataIC50: 490nMAssay Description:Inhibition of rat small intestinal sucrase assessed as reduction of p-nitrophenol release using p-nitrophenyl-glycoside as substrate by spectrophotom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50598381(CHEMBL5172851)
Affinity DataIC50: 770nMAssay Description:Inhibition of human GCase assessed as reduction of 4-methylumbelliferone liberation using 4-methylumbelliferyl-beta-glucopyranoside as substrate prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50598384(CHEMBL5190439)
Affinity DataIC50: 820nMAssay Description:Inhibition of human GCaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50598389(CHEMBL3751947)
Affinity DataIC50: 880nMAssay Description:Inhibition of rat small intestinal maltase assessed as reduction of D-glucose release using maltose as substrate by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50598380(CHEMBL5176016)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human GCase assessed as reduction of 4-methylumbelliferone liberation using 4-methylumbelliferyl-beta-glucopyranoside as substrate prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50182798(1,5-Dideoxy-1,5-imino-D-xylitol | PIPERIDINE-3,4,5...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human GCaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50598378(CHEMBL5203567)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human GCase assessed as reduction of 4-methylumbelliferone liberation using 4-methylumbelliferyl-beta-glucopyranoside as substrate prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50598379(CHEMBL5208500)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human GCase assessed as reduction of 4-methylumbelliferone liberation using 4-methylumbelliferyl-beta-glucopyranoside as substrate prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetMaltase-glucoamylase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50598389(CHEMBL3751947)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human lysosomal alpha-glucosidase assessed as reduction of p-nitrophenol release using p-nitrophenyl-glycoside as substrate by spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50016703(CHEMBL80254 | Imino-D-Arabinitol | BDBM50031485 | ...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of rat small intestinal sucrase assessed as reduction of p-nitrophenol release using p-nitrophenyl-glycoside as substrate by spectrophotom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50598377(CHEMBL5206557)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human GCase assessed as reduction of 4-methylumbelliferone liberation using 4-methylumbelliferyl-beta-glucopyranoside as substrate prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50598376(CHEMBL5206213)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of human GCase assessed as reduction of 4-methylumbelliferone liberation using 4-methylumbelliferyl-beta-glucopyranoside as substrate prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50016703(CHEMBL80254 | Imino-D-Arabinitol | BDBM50031485 | ...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of rat small intestinal maltase assessed as reduction of D-glucose release using maltose as substrate by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50598383(CHEMBL5199229)
Affinity DataIC50: 2.65E+4nMAssay Description:Inhibition of human GCaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50598374(CHEMBL5201364)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human GCase assessed as reduction of 4-methylumbelliferone liberation using 4-methylumbelliferyl-beta-glucopyranoside as substrate prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50598373(CHEMBL5202795)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of human GCase assessed as reduction of 4-methylumbelliferone liberation using 4-methylumbelliferyl-beta-glucopyranoside as substrate prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50598375(CHEMBL5185978)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of human GCase assessed as reduction of 4-methylumbelliferone liberation using 4-methylumbelliferyl-beta-glucopyranoside as substrate prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50598372(CHEMBL5175538)
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of human GCase assessed as reduction of 4-methylumbelliferone liberation using 4-methylumbelliferyl-beta-glucopyranoside as substrate prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetMaltase-glucoamylase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50016703(CHEMBL80254 | Imino-D-Arabinitol | BDBM50031485 | ...)
Affinity DataIC50: 5.60E+4nMAssay Description:Inhibition of human lysosomal alpha-glucosidase assessed as reduction of p-nitrophenol release using p-nitrophenyl-glycoside as substrate by spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50598390(CHEMBL5187298)
Affinity DataIC50: 1.17E+5nMAssay Description:Inhibition of rat small intestinal sucrase assessed as reduction of p-nitrophenol release using p-nitrophenyl-glycoside as substrate by spectrophotom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50598387(CHEMBL5190584)
Affinity DataIC50: 1.78E+5nMAssay Description:Inhibition of rat small intestinal sucrase assessed as reduction of p-nitrophenol release using p-nitrophenyl-glycoside as substrate by spectrophotom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataIC50: 2.40E+5nMAssay Description:Inhibition of human GCase assessed as reduction of 4-methylumbelliferone liberation using 4-methylumbelliferyl-beta-glucopyranoside as substrate prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50598388(CHEMBL5181276)
Affinity DataIC50: 2.64E+5nMAssay Description:Inhibition of rat small intestinal sucrase assessed as reduction of p-nitrophenol release using p-nitrophenyl-glycoside as substrate by spectrophotom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM18355(N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...)
Affinity DataIC50: 2.70E+5nMAssay Description:Inhibition of human GCase assessed as reduction of 4-methylumbelliferone liberation using 4-methylumbelliferyl-beta-glucopyranoside as substrate prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50598393(CHEMBL5188105)
Affinity DataIC50: 3.39E+5nMAssay Description:Inhibition of rat small intestinal sucrase assessed as reduction of p-nitrophenol release using p-nitrophenyl-glycoside as substrate by spectrophotom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50598391(CHEMBL5172703)
Affinity DataIC50: 3.89E+5nMAssay Description:Inhibition of rat small intestinal sucrase assessed as reduction of p-nitrophenol release using p-nitrophenyl-glycoside as substrate by spectrophotom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetAlpha-mannosidase(Jack bean)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50016703(CHEMBL80254 | Imino-D-Arabinitol | BDBM50031485 | ...)
Affinity DataIC50: 4.74E+5nMAssay Description:Inhibition of jack bean alpha-mannosidase assessed as reduction of p-nitrophenol release using p-nitrophenyl-glycoside as substrate by spectrophotome...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50598388(CHEMBL5181276)
Affinity DataIC50: 5.71E+5nMAssay Description:Inhibition of rat small intestinal maltase assessed as reduction of D-glucose release using maltose as substrate by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50598392(CHEMBL5169411)
Affinity DataIC50: 5.80E+5nMAssay Description:Inhibition of rat small intestinal sucrase assessed as reduction of p-nitrophenol release using p-nitrophenyl-glycoside as substrate by spectrophotom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50598383(CHEMBL5199229)
Affinity DataIC50: 6.03E+5nMAssay Description:Inhibition of rat small intestinal sucrase assessed as reduction of p-nitrophenol release using p-nitrophenyl-glycoside as substrate by spectrophotom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50598387(CHEMBL5190584)
Affinity DataIC50: 6.09E+5nMAssay Description:Inhibition of rat small intestinal maltase assessed as reduction of D-glucose release using maltose as substrate by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50598394(CHEMBL5192355)
Affinity DataIC50: 1.21E+6nMAssay Description:Inhibition of rat small intestinal sucrase assessed as reduction of p-nitrophenol release using p-nitrophenyl-glycoside as substrate by spectrophotom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed