Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50016797
TargetSodium-dependent serotonin transporter(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50597226(CHEMBL5188930)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of human SERT transfected in HEK cells using APP+ as fluorescent substrate preincubated for 1 hr followed by substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50597221(CHEMBL5175119)
Affinity DataIC50: 26nMAssay Description:Inhibition of human SERT transfected in HEK cells using APP+ as fluorescent substrate preincubated for 1 hr followed by substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50597225(CHEMBL5207764)
Affinity DataIC50: 59nMAssay Description:Inhibition of human SERT transfected in HEK cells using APP+ as fluorescent substrate preincubated for 1 hr followed by substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetSynaptic vesicular amine transporter(Rat)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50597228(CHEMBL5176306)
Affinity DataIC50: 70nMAssay Description:Inhibition of rat VMAT2 transfected in HEK cells using FFN206 as fluorescent substrate preincubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50597223(CHEMBL5201219)
Affinity DataIC50: 80nMAssay Description:Inhibition of human SERT transfected in HEK cells using APP+ as fluorescent substrate preincubated for 1 hr followed by substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetSynaptic vesicular amine transporter(Rat)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50597220(CHEMBL5207655)
Affinity DataIC50: 80nMAssay Description:Inhibition of rat VMAT2 transfected in HEK cells using FFN206 as fluorescent substrate preincubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetSynaptic vesicular amine transporter(Rat)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50597225(CHEMBL5207764)
Affinity DataIC50: 170nMAssay Description:Inhibition of rat VMAT2 transfected in HEK cells using FFN206 as fluorescent substrate preincubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50597219(CHEMBL5202868)
Affinity DataIC50: 280nMAssay Description:Inhibition of human SERT transfected in HEK cells using APP+ as fluorescent substrate preincubated for 1 hr followed by substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50597222(CHEMBL5184088)
Affinity DataIC50: 330nMAssay Description:Inhibition of human SERT transfected in HEK cells using APP+ as fluorescent substrate preincubated for 1 hr followed by substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetSynaptic vesicular amine transporter(Rat)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50597226(CHEMBL5188930)
Affinity DataIC50: 440nMAssay Description:Inhibition of rat VMAT2 transfected in HEK cells using FFN206 as fluorescent substrate preincubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50308247(CHEMBL1215855 | ibogaine)
Affinity DataIC50: 500nMAssay Description:Inhibition of human SERT transfected in HEK cells using APP+ as fluorescent substrate preincubated for 1 hr followed by substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSynaptic vesicular amine transporter(Rat)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50597219(CHEMBL5202868)
Affinity DataIC50: 570nMAssay Description:Inhibition of rat VMAT2 transfected in HEK cells using FFN206 as fluorescent substrate preincubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50597229(CHEMBL5188726)
Affinity DataIC50: 670nMAssay Description:Inhibition of human SERT transfected in HEK cells using APP+ as fluorescent substrate preincubated for 1 hr followed by substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetSynaptic vesicular amine transporter(Rat)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50597224(CHEMBL5171433)
Affinity DataIC50: 740nMAssay Description:Inhibition of rat VMAT2 transfected in HEK cells using FFN206 as fluorescent substrate preincubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetSynaptic vesicular amine transporter(Rat)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50597227(CHEMBL5180373)
Affinity DataIC50: 750nMAssay Description:Inhibition of rat VMAT2 transfected in HEK cells using FFN206 as fluorescent substrate preincubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50597227(CHEMBL5180373)
Affinity DataIC50: 910nMAssay Description:Inhibition of human SERT transfected in HEK cells using APP+ as fluorescent substrate preincubated for 1 hr followed by substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50597224(CHEMBL5171433)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human SERT transfected in HEK cells using APP+ as fluorescent substrate preincubated for 1 hr followed by substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetSynaptic vesicular amine transporter(Rat)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50597223(CHEMBL5201219)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of rat VMAT2 transfected in HEK cells using FFN206 as fluorescent substrate preincubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50597228(CHEMBL5176306)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human SERT transfected in HEK cells using APP+ as fluorescent substrate preincubated for 1 hr followed by substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetSynaptic vesicular amine transporter(Rat)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50597222(CHEMBL5184088)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of rat VMAT2 transfected in HEK cells using FFN206 as fluorescent substrate preincubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetSynaptic vesicular amine transporter(Rat)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50597221(CHEMBL5175119)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of rat VMAT2 transfected in HEK cells using FFN206 as fluorescent substrate preincubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetSynaptic vesicular amine transporter(Rat)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50308247(CHEMBL1215855 | ibogaine)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of rat VMAT2 transfected in HEK cells using FFN206 as fluorescent substrate preincubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetSynaptic vesicular amine transporter(Rat)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50597229(CHEMBL5188726)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of rat VMAT2 transfected in HEK cells using FFN206 as fluorescent substrate preincubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50597220(CHEMBL5207655)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human SERT transfected in HEK cells using APP+ as fluorescent substrate preincubated for 1 hr followed by substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed