Compile Data Set for Download or QSAR
Report error Found 70 Enz. Inhib. hit(s) with all data for entry = 50017287
TargetNuclear receptor subfamily 1 group I member 2(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM176003(US9688695, 36 | US10047103, 36)
Affinity DataEC50: >1.50E+4nMAssay Description:Agonist activity at PXR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM176061(US9688695, 94 | US10047103, 94)
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at PXR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM176003(US9688695, 36 | US10047103, 36)
Affinity DataKd:  0.0860nMAssay Description:Binding affinity to PAR4 (unknown origin) assessed as association constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM176061(US9688695, 94 | US10047103, 94)
Affinity DataKd:  0.0700nMAssay Description:Binding affinity to PAR4 (unknown origin) assessed as association constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM176003(US9688695, 36 | US10047103, 36)
Affinity DataKd:  0.100nMAssay Description:Binding affinity to PAR4 (unknown origin) assessed as saturation bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM176061(US9688695, 94 | US10047103, 94)
Affinity DataKd:  0.0980nMAssay Description:Binding affinity to PAR4 (unknown origin) assessed as saturation bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM176023(US9688695, 56 | US10047103, 56)
Affinity DataIC50: 0.200nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM176039(US9688695, 72 | US10047103, 72)
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM176082(US9688695, 115 | US10047103, 115)
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM175970(US9688695, 3 | US10047103, 3 | US9605024, Example ...)
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM176053(US9688695, 86 | US10047103, 86)
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM176003(US9688695, 36 | US10047103, 36)
Affinity DataIC50: 0.400nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM176007(US9688695, 40 | US10047103, 40)
Affinity DataIC50: 0.400nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM50600788(CHEMBL5206065)
Affinity DataIC50: 0.400nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM176061(US9688695, 94 | US10047103, 94)
Affinity DataIC50: 0.400nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM175988(US9688695, 21 | US10047103, 21)
Affinity DataIC50: 0.400nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM50600792(CHEMBL5189522)
Affinity DataIC50: 0.400nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM176019(US9688695, 52 | US10047103, 52)
Affinity DataIC50: 0.5nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM286418(US9518064, Example 34)
Affinity DataIC50: 0.5nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM176026(US9688695, 59 | US10047103, 59)
Affinity DataIC50: 0.5nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM286419(US9518064, Example 35)
Affinity DataIC50: 0.5nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM286424(US9518064, Example 40)
Affinity DataIC50: 0.5nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM50600791(CHEMBL5177223)
Affinity DataIC50: 0.600nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM175972(US9688695, 5 | US10047103, 5)
Affinity DataIC50: 0.600nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM176258(US9688695, 291 | US10047103, 291)
Affinity DataIC50: 0.600nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM176059(US9688695, 92 | US10047103, 92)
Affinity DataIC50: 0.600nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM176268(US9688695, 301 | US10047103, 301)
Affinity DataIC50: 0.600nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM176063(US9688695, 96 | US10047103, 96)
Affinity DataIC50: 0.600nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM175990(US9688695, 23 | US10047103, 23)
Affinity DataIC50: 0.600nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM286427(US9518064, Example 43)
Affinity DataIC50: 0.600nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM50600784(CHEMBL5184586)
Affinity DataIC50: 0.630nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM175989(US9688695, 22 | US10047103, 22)
Affinity DataIC50: 0.700nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM286431(US9518064, Example 47)
Affinity DataIC50: 0.700nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM50600790(CHEMBL5171201)
Affinity DataIC50: 0.700nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM176048(US9688695, 81 | US10047103, 81)
Affinity DataIC50: 0.800nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM176032(US9688695, 65 | US10047103, 65)
Affinity DataIC50: 0.800nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM286394(US9518064, Example 6)
Affinity DataIC50: 0.800nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM50600785(CHEMBL5173906)
Affinity DataIC50: 0.800nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM286482(2-Methoxy-6-(6-methoxy-4-((2-phenylpyrimidin-4-yl)...)
Affinity DataIC50: 0.900nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM286387(2-Methoxy-6-(6-methoxy-4-((3-(pyrimidin-5-yl)benzy...)
Affinity DataIC50: 1.10nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM50600793(CHEMBL5205126)
Affinity DataIC50: 1.10nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM175971(US9688695, 4 | US10047103, 4)
Affinity DataIC50: 1.10nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM175978(US9688695, 11 | US10047103, 11)
Affinity DataIC50: 1.30nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM175981(US9688695, 14 | US10047103, 14)
Affinity DataIC50: 1.30nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM175974(US9688695, 7 | US10047103, 7)
Affinity DataIC50: 1.5nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM286437(US9518064, Example 53)
Affinity DataIC50: 1.5nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM50600789(CHEMBL5188943)
Affinity DataIC50: 1.70nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM175968(US9688695, 1 | US10047103, 1)
Affinity DataIC50: 1.80nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM176005(US9688695, 38 | US10047103, 38)
Affinity DataIC50: 2.40nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM364746(US9862730, Example 205 | 6-(4-((3-(Benzyloxy)benzy...)
Affinity DataIC50: 2.40nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
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