Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50019656
TargetHepatocyte growth factor receptor(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50146167(Capmatinib | INC-280 | INCB-28060 | NVP-INC280 | U...)
Affinity DataIC50: 0.130nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHepatocyte growth factor receptor(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50427138(CHEMBL2323775 | MK-8033)
Affinity DataIC50: 1nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50021574(CHEBI:72317 | CABOZANTINIB | BMS-907351 | Cometriq...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM28031(N-{4-[(2-amino-3-chloropyridin-4-yl)oxy]-3-fluorop...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of RON (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50021574(CHEBI:72317 | CABOZANTINIB | BMS-907351 | Cometriq...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of c-MET (unknown origin) by kinome scan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50621415(CHEMBL5395266)
Affinity DataIC50: 2nMAssay Description:Inhibition of RON (unknown origin) by kinome scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of RON (unknown origin) by kinome scan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50621413(CHEMBL5409449)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of RON (unknown origin) by kinome scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50621415(CHEMBL5395266)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of c-MET (unknown origin) by kinome scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM28031(N-{4-[(2-amino-3-chloropyridin-4-yl)oxy]-3-fluorop...)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHepatocyte growth factor receptor(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50065457(EMD-1214063 | MSC-2156119 | MSC-2156119J | Tepotin...)
Affinity DataIC50: 4nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM163243(US9062045, Comparator No. 1 (JNJ-38877605))
Affinity DataIC50: 4nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50621413(CHEMBL5409449)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of c-MET (unknown origin) by kinome scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50621414(CHEMBL5433417)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of RON (unknown origin) by kinome scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50621412(CHEMBL5414779)
Affinity DataIC50: 6nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50427138(CHEMBL2323775 | MK-8033)
Affinity DataIC50: 7nMAssay Description:Inhibition of RON (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 8nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50621414(CHEMBL5433417)
Affinity DataIC50: 10nMAssay Description:Inhibition of c-MET (unknown origin) by kinome scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50621413(CHEMBL5409449)
Affinity DataIC50: 27nMAssay Description:Inhibition of AXL (unknown origin) by kinome scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50621413(CHEMBL5409449)
Affinity DataIC50: 28nMAssay Description:Inhibition of RET (unknown origin) by kinome scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50621413(CHEMBL5409449)
Affinity DataIC50: 110nMAssay Description:Inhibition of PDGFRbeta (unknown origin) by kinome scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50621413(CHEMBL5409449)
Affinity DataIC50: 145nMAssay Description:Inhibition of ABL (unknown origin) by kinome scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50621413(CHEMBL5409449)
Affinity DataIC50: 362nMAssay Description:Inhibition of FLT3 (unknown origin) by kinome scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM24772(2-[(4-fluorophenyl)amino]-5-[5-({6-methoxy-7-[3-(m...)
Affinity DataKi:  3.40nMAssay Description:Binding affinity to c-Met (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed