Compile Data Set for Download or QSAR
Report error Found 78 Enz. Inhib. hit(s) with all data for entry = 50016138
TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592748(CHEMBL5193123)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of EGFR del18/T790M/C797S triple mutant (unknown origin) using TK as substrate incubated for 120 mins in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592743(CHEMBL5186680)
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of EGFR del18/T790M/C797S triple mutant (unknown origin) using TK as substrate incubated for 120 mins in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592747(CHEMBL5195904)
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) using TK as substrate incubated for 120 mins in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592741(CHEMBL5180388)
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) using TK as substrate incubated for 120 mins in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592752(CHEMBL5188940)
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of EGFR del18/T790M/C797S triple mutant (unknown origin) using TK as substrate incubated for 120 mins in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592752(CHEMBL5188940)
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) using TK as substrate incubated for 120 mins in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592743(CHEMBL5186680)
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) using TK as substrate incubated for 120 mins in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592745(CHEMBL5188373)
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) using TK as substrate incubated for 120 mins in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592736(CHEMBL5209094)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of EGFR del18/T790M/C797S triple mutant (unknown origin) using TK as substrate incubated for 120 mins in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592748(CHEMBL5193123)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) using TK as substrate incubated for 120 mins in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592738(CHEMBL5199678)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of EGFR del18/T790M/C797S triple mutant (unknown origin) using TK as substrate incubated for 120 mins in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592741(CHEMBL5180388)
Affinity DataIC50: 0.110nMAssay Description:Inhibition of EGFR del18/T790M/C797S triple mutant (unknown origin) using TK as substrate incubated for 120 mins in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592751(CHEMBL5193149)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of EGFR del18/T790M/C797S triple mutant (unknown origin) using TK as substrate incubated for 120 mins in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592754(CHEMBL5197545)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) using TK as substrate incubated for 120 mins in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592749(CHEMBL5192223)
Affinity DataIC50: 0.130nMAssay Description:Inhibition of EGFR del18/T790M/C797S triple mutant (unknown origin) using TK as substrate incubated for 120 mins in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592751(CHEMBL5193149)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) using TK as substrate incubated for 120 mins in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592754(CHEMBL5197545)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of EGFR del18/T790M/C797S triple mutant (unknown origin) using TK as substrate incubated for 120 mins in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592740(CHEMBL5203220)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) using TK as substrate incubated for 120 mins in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592737(CHEMBL5195137)
Affinity DataIC50: 0.180nMAssay Description:Inhibition of EGFR del18/T790M/C797S triple mutant (unknown origin) using TK as substrate incubated for 120 mins in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592749(CHEMBL5192223)
Affinity DataIC50: 0.190nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) using TK as substrate incubated for 120 mins in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592746(CHEMBL5206164)
Affinity DataIC50: 0.220nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) using TK as substrate incubated for 120 mins in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592742(CHEMBL5180894)
Affinity DataIC50: 0.270nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) using TK as substrate incubated for 120 mins in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592750(CHEMBL5204749)
Affinity DataIC50: 0.280nMAssay Description:Inhibition of EGFR del18/T790M/C797S triple mutant (unknown origin) using TK as substrate incubated for 120 mins in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592755(CHEMBL5178971)
Affinity DataIC50: 0.280nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) using TK as substrate incubated for 120 mins in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592746(CHEMBL5206164)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of EGFR del18/T790M/C797S triple mutant (unknown origin) using TK as substrate incubated for 120 mins in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592745(CHEMBL5188373)
Affinity DataIC50: 0.310nMAssay Description:Inhibition of EGFR del18/T790M/C797S triple mutant (unknown origin) using TK as substrate incubated for 120 mins in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592740(CHEMBL5203220)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of EGFR del18/T790M/C797S triple mutant (unknown origin) using TK as substrate incubated for 120 mins in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592750(CHEMBL5204749)
Affinity DataIC50: 0.410nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) using TK as substrate incubated for 120 mins in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592753(CHEMBL5203385)
Affinity DataIC50: 0.410nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) using TK as substrate incubated for 120 mins in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592744(CHEMBL5179357)
Affinity DataIC50: 0.430nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) using TK as substrate incubated for 120 mins in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592747(CHEMBL5195904)
Affinity DataIC50: 0.430nMAssay Description:Inhibition of EGFR del18/T790M/C797S triple mutant (unknown origin) using TK as substrate incubated for 120 mins in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592753(CHEMBL5203385)
Affinity DataIC50: 0.490nMAssay Description:Inhibition of EGFR del18/T790M/C797S triple mutant (unknown origin) using TK as substrate incubated for 120 mins in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetFocal adhesion kinase 1(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592745(CHEMBL5188373)
Affinity DataIC50: 0.510nMAssay Description:Inhibition of FAK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592744(CHEMBL5179357)
Affinity DataIC50: 0.650nMAssay Description:Inhibition of EGFR del18/T790M/C797S triple mutant (unknown origin) using TK as substrate incubated for 120 mins in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592739(CHEMBL5203041)
Affinity DataIC50: 0.670nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) using TK as substrate incubated for 120 mins in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592736(CHEMBL5209094)
Affinity DataIC50: 0.670nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) using TK as substrate incubated for 120 mins in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50185140(AP-26113 | Brigatinib | US11248003, Example Brigat...)
Affinity DataIC50: 0.820nMAssay Description:Inhibition of EGFR del18/T790M/C797S triple mutant (unknown origin) using TK as substrate incubated for 120 mins in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592742(CHEMBL5180894)
Affinity DataIC50: 0.830nMAssay Description:Inhibition of EGFR del18/T790M/C797S triple mutant (unknown origin) using TK as substrate incubated for 120 mins in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592738(CHEMBL5199678)
Affinity DataIC50: 0.840nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) using TK as substrate incubated for 120 mins in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592739(CHEMBL5203041)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of EGFR del18/T790M/C797S triple mutant (unknown origin) using TK as substrate incubated for 120 mins in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592737(CHEMBL5195137)
Affinity DataIC50: 0.930nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) using TK as substrate incubated for 120 mins in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592745(CHEMBL5188373)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of PDGFRbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetTyrosine-protein kinase Fer(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592745(CHEMBL5188373)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of FER (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50185140(AP-26113 | Brigatinib | US11248003, Example Brigat...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) using TK as substrate incubated for 120 mins in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase JAK2(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592745(CHEMBL5188373)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRibosomal protein S6 kinase alpha-1(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592745(CHEMBL5188373)
Affinity DataIC50: 4nMAssay Description:Inhibition of RSK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592745(CHEMBL5188373)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of ROS (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592745(CHEMBL5188373)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of RET (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetProtein-tyrosine kinase 6(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592745(CHEMBL5188373)
Affinity DataIC50: 11nMAssay Description:Inhibition of BRK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50592745(CHEMBL5188373)
Affinity DataIC50: 41nMAssay Description:Inhibition of AXL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
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