Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50015958
TargetStimulator of interferon genes protein(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM453551(4-(5,6-dimethoxybenzo[b]thiophen-2-yl)-4- oxobutan...)
Affinity DataEC50:  8.14E+3nMAssay Description:Agonist activity at STING in human THP1-Dual cells assessed as ISG pathway activation incubated for 24 hrs by Quanti-Luc or Quanti-blue reagent based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetStimulator of interferon genes protein(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50590830(CHEMBL5182896)
Affinity DataEC50:  2.55E+3nMAssay Description:Agonist activity at STING in human THP1-Dual cells assessed as ISG pathway activation incubated for 24 hrs by Quanti-Luc or Quanti-blue reagent based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50590831(CHEMBL5183242)
Affinity DataEC50:  6.14E+3nMAssay Description:Agonist activity at STING in human THP1-Dual cells assessed as ISG pathway activation incubated for 24 hrs by Quanti-Luc or Quanti-blue reagent based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50582513(CHEMBL5093161)
Affinity DataEC50:  5.34E+3nMAssay Description:Agonist activity at STING in human THP1-Dual cells assessed as ISG pathway activation incubated for 24 hrs by Quanti-Luc or Quanti-blue reagent based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50509050(CHEMBL4438309)
Affinity DataEC50:  130nMAssay Description:Agonist activity at human wild type haplotype STING in human PBMC cells assessed as increase in IFN-beta secretion incubated for 3 hrs by luminescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50590832(CHEMBL5200360)
Affinity DataEC50:  8nMAssay Description:Agonist activity at STING in human THP-1 cells assessed as increase in IFN-beta secretion incubated for 5 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed