Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50019657
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM14774(DAXAS | 3-(cyclopropylmethoxy)-N-(3,5-dichloropyri...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of PDE4D2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50621426(CHEMBL5431083)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant PDE4D2 (86 to 413 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]cAMP as substrate incubated for 1...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50621424(CHEMBL5400816)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant PDE4D2 (86 to 413 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]cAMP as substrate incubated for 1...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50621423(CHEMBL5407967)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of recombinant PDE4D2 (86 to 413 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]cAMP as substrate incubated for 1...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50621422(CHEMBL5408080)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of recombinant PDE4D2 (86 to 413 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]cAMP as substrate incubated for 1...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50621431(CHEMBL5421333)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of recombinant PDE4D2 (86 to 413 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]cAMP as substrate incubated for 1...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50621427(CHEMBL5420700)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of recombinant PDE4D2 (86 to 413 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]cAMP as substrate incubated for 1...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50621432(CHEMBL5440771)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of recombinant PDE4D2 (86 to 413 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]cAMP as substrate incubated for 1...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50621430(CHEMBL5435764)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of recombinant PDE4D2 (86 to 413 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]cAMP as substrate incubated for 1...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50621423(CHEMBL5407967)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of recombinant PDE4B2 (152 to 487 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]cAMP as substrate incubated for ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50621421(CHEMBL5434362)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant PDE4D2 (86 to 413 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]cAMP as substrate incubated for 1...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50621425(CHEMBL5434713)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant PDE4D2 (86 to 413 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]cAMP as substrate incubated for 1...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50621420(CHEMBL5438159)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant PDE4D2 (86 to 413 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]cAMP as substrate incubated for 1...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50621428(CHEMBL5410553)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant PDE4D2 (86 to 413 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]cAMP as substrate incubated for 1...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50621423(CHEMBL5407967)
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant PDE7A1 (130 to 482 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]cAMP as substrate incubated for ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50621429(CHEMBL5405731)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant PDE4D2 (86 to 413 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]cAMP as substrate incubated for 1...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50621419(CHEMBL5437810)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant PDE4D2 (86 to 413 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]cAMP as substrate incubated for 1...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50621423(CHEMBL5407967)
Affinity DataIC50: 194nMAssay Description:Inhibition of recombinant PDE8A1 (480 to 828 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]cAMP as substrate incubated for ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50621418(CHEMBL5428117)
Affinity DataIC50: 203nMAssay Description:Inhibition of recombinant PDE4D2 (86 to 413 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]cAMP as substrate incubated for 1...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50311741(9-hydroxycalabaxanthone | 1,6-dihydroxy-7-methoxy-...)
Affinity DataIC50: 420nMAssay Description:Inhibition of recombinant PDE4D2 (86 to 413 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]cAMP as substrate incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50248919((S)-N-(2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsu...)
Affinity DataIC50: 500nMAssay Description:Inhibition of PDE4D2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 590nMAssay Description:Inhibition of recombinant PDE4D2 (86 to 413 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]cAMP as substrate incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 590nMAssay Description:Inhibition of PDE4D2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50621416(CHEMBL5437828)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant PDE4D2 (86 to 413 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]cAMP as substrate incubated for 1...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50621417(CHEMBL5420621)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant PDE4D2 (86 to 413 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]cAMP as substrate incubated for 1...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50621423(CHEMBL5407967)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of recombinant PDE10A2 (449 to 770 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]cAMP as substrate incubated for...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50621423(CHEMBL5407967)
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of recombinant PDE5A1 (535 to 860 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]cGMP as substrate incubated for ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM23620(Dipyridamine | SMR000058382 | MLS000028420 | CHEMB...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of PDE4D2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCytochrome P450 2C9(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50621423(CHEMBL5407967)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human CYP2C9 in human hepatocytesMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50621423(CHEMBL5407967)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of human CYP3A4 in human hepatocytesMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50621423(CHEMBL5407967)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant PDE1C (147 to 531 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]cGMP as substrate incubated for 1...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50621423(CHEMBL5407967)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant PDE2A (580 to 919 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]cGMP as substrate incubated for 1...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50621423(CHEMBL5407967)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant PDE3A (679 to 1087 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]cAMP as substrate incubated for ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50621423(CHEMBL5407967)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant PDE9A2 (181 to 506 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]cGMP as substrate incubated for ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCytochrome P450 2B6(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50621423(CHEMBL5407967)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human CYP2B6 in human hepatocytesMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCytochrome P450 1A2(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50621423(CHEMBL5407967)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human CYP1A2 in human hepatocytesMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCytochrome P450 2D6(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50621423(CHEMBL5407967)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human CYP2D6 in human hepatocytesMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50621423(CHEMBL5407967)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed