Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50017039
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599287(CHEMBL5183592 | US12318398, Compound 25)
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599294(CHEMBL5207166 | US12318398, Compound 1)
Affinity DataIC50: 42nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599288(CHEMBL5189483)
Affinity DataIC50: 51nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599307(CHEMBL5176278)
Affinity DataIC50: 53nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599290(CHEMBL5204087 | US12318398, Compound 22)
Affinity DataIC50: 56nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599291(CHEMBL5188177)
Affinity DataIC50: 57nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599308(CHEMBL5200426)
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599285(CHEMBL5200209 | US12318398, Compound 21)
Affinity DataIC50: 75nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599278(CHEMBL5187804 | US12318398, Compound 16)
Affinity DataIC50: 77nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599303(CHEMBL5170557 | US12318398, Compound 33)
Affinity DataIC50: 79nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599295(CHEMBL5188315 | US12318398, Compound 20)
Affinity DataIC50: 88nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599297(CHEMBL5170173 | US12318398, Compound 7)
Affinity DataIC50: 103nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50583996(CHEMBL4554938 | US12318398, Compound XMU-MP-1)
Affinity DataIC50: 104nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599304(CHEMBL5191297)
Affinity DataIC50: 104nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599305(CHEMBL5179668)
Affinity DataIC50: 119nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599299(CHEMBL5182825 | US12318398, Compound 14)
Affinity DataIC50: 129nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599286(CHEMBL5196108)
Affinity DataIC50: 129nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599281(CHEMBL5201386 | US12318398, Compound 11)
Affinity DataIC50: 134nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599271(CHEMBL5198452 | US12318398, Compound 19)
Affinity DataIC50: 136nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599298(CHEMBL5180293 | US12318398, Compound 15)
Affinity DataIC50: 141nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599309(CHEMBL5204593)
Affinity DataIC50: 153nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599292(CHEMBL5205996)
Affinity DataIC50: 168nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599302(CHEMBL5177601)
Affinity DataIC50: 181nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599275(CHEMBL5207430 | US12318398, Compound 17)
Affinity DataIC50: 206nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599277(CHEMBL5190201)
Affinity DataIC50: 211nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599306(CHEMBL5206194)
Affinity DataIC50: 219nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599287(CHEMBL5183592 | US12318398, Compound 25)
Affinity DataKd:  240nMAssay Description:Binding affinity to wild-type human full length MST1 (M1 to F487 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599289(CHEMBL5175313)
Affinity DataIC50: 251nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599276(CHEMBL5192708)
Affinity DataIC50: 254nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599310(CHEMBL5174798)
Affinity DataIC50: 256nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599300(CHEMBL5173815)
Affinity DataIC50: 272nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599273(CHEMBL5171473)
Affinity DataIC50: 313nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599301(CHEMBL5201188)
Affinity DataIC50: 318nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599279(CHEMBL5171488)
Affinity DataIC50: 383nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599293(CHEMBL5186448)
Affinity DataIC50: 419nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599274(CHEMBL5208473)
Affinity DataIC50: 479nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599272(CHEMBL5204658)
Affinity DataIC50: 495nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599287(CHEMBL5183592 | US12318398, Compound 25)
Affinity DataIC50: 652nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST2 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599283(CHEMBL5207903)
Affinity DataIC50: 954nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599282(CHEMBL5173960)
Affinity DataIC50: 989nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599280(CHEMBL5206899)
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599287(CHEMBL5183592 | US12318398, Compound 25)
Affinity DataKd:  2.70E+3nMAssay Description:Binding affinity to wild-type human partial length MST2 (D17 to E318 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599284(CHEMBL5188724)
Affinity DataIC50: 2.71E+3nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase Nek3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599287(CHEMBL5183592 | US12318398, Compound 25)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human NEK3 expressed in baculovirus expression system using S2 as substrate incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599296(CHEMBL5173057)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed