Compile Data Set for Download or QSAR
Report error Found 116 Enz. Inhib. hit(s) with all data for entry = 50016184
TargetHigh affinity nerve growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593050(CHEMBL5174525)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593047(CHEMBL5172448)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593051(CHEMBL5171942)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50525707(CHEMBL4457566)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHigh affinity nerve growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593035(CHEMBL5183149)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593043(CHEMBL5189763)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50525707(CHEMBL4457566)
Affinity DataIC50: 2nMAssay Description:Inhibition of TRKB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593029(CHEMBL5195158)
Affinity DataIC50: 2nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593031(CHEMBL5191460)
Affinity DataIC50: 2nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593039(CHEMBL5199099)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593053(CHEMBL5198357)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593045(CHEMBL5205778)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593046(CHEMBL5199353)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593052(CHEMBL5178903)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593030(CHEMBL5193231)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593037(CHEMBL5171199)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593054(CHEMBL5173139)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetNT-3 growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50525707(CHEMBL4457566)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of TRKC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593042(CHEMBL5169941)
Affinity DataIC50: 3nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593033(CHEMBL5173016)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593032(CHEMBL5171966)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593041(CHEMBL5198427)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593049(CHEMBL5203355)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593048(CHEMBL5174514)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593044(CHEMBL5199002)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593038(CHEMBL5197535)
Affinity DataIC50: 4nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593027(CHEMBL5186340)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetNT-3 growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593027(CHEMBL5186340)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of TRKC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593027(CHEMBL5186340)
Affinity DataIC50: 8.10nMAssay Description:Inhibition of TRKB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593040(CHEMBL5189733)
Affinity DataIC50: 13nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593034(CHEMBL5202910)
Affinity DataIC50: 15nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593036(CHEMBL5180301)
Affinity DataIC50: 18nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetTyrosine-protein kinase Lck(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593038(CHEMBL5197535)
Affinity DataIC50: 22nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetTyrosine-protein kinase Lck(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593043(CHEMBL5189763)
Affinity DataIC50: 50nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetTyrosine-protein kinase Lck(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593030(CHEMBL5193231)
Affinity DataIC50: 53nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetTyrosine-protein kinase Lck(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593054(CHEMBL5173139)
Affinity DataIC50: 58nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetTyrosine-protein kinase Lck(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593039(CHEMBL5199099)
Affinity DataIC50: 68nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetTyrosine-protein kinase Lck(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593042(CHEMBL5169941)
Affinity DataIC50: 86nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetTyrosine-protein kinase Lck(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593051(CHEMBL5171942)
Affinity DataIC50: 96nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetTyrosine-protein kinase Lck(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593037(CHEMBL5171199)
Affinity DataIC50: 96nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetTyrosine-protein kinase Lck(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593047(CHEMBL5172448)
Affinity DataIC50: 130nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetTyrosine-protein kinase Lck(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593052(CHEMBL5178903)
Affinity DataIC50: 130nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetTyrosine-protein kinase Lck(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593040(CHEMBL5189733)
Affinity DataIC50: 140nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetTyrosine-protein kinase Lck(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593046(CHEMBL5199353)
Affinity DataIC50: 145nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetTyrosine-protein kinase Lck(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593045(CHEMBL5205778)
Affinity DataIC50: 159nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetTyrosine-protein kinase Lck(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593029(CHEMBL5195158)
Affinity DataIC50: 160nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593028(CHEMBL5203369)
Affinity DataIC50: 160nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetTyrosine-protein kinase Lck(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593036(CHEMBL5180301)
Affinity DataIC50: 170nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593030(CHEMBL5193231)
Affinity DataIC50: 171nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetTyrosine-protein kinase Lck(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50593035(CHEMBL5183149)
Affinity DataIC50: 180nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
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