Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50018006
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50606920(CHEMBL5219960)
Affinity DataEC50:  2.13E+4nMAssay Description:Agonist activity at STING in human THP-1 cells harboring IRF-inducible luciferase reporter construct assessed as increase in ISG signalling incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50606921(CHEMBL5219485)
Affinity DataEC50:  9.24E+3nMAssay Description:Agonist activity at STING in human THP-1 cells harboring IRF-inducible luciferase reporter construct assessed as increase in relative fluorescence un...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetStimulator of interferon genes protein(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50606921(CHEMBL5219485)
Affinity DataEC50:  5.71E+3nMAssay Description:Agonist activity at STING in mouse RAW264.7 cells harboring IRF-inducible luciferase reporter construct assessed as increase in relative fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50606921(CHEMBL5219485)
Affinity DataEC50:  5.19E+3nMAssay Description:Agonist activity at STING in cGAS knockout human THP-1 cells harboring IRF-inducible luciferase reporter construct assessed as increase in relative f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50606921(CHEMBL5219485)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at STING in STING knockout human THP-1 cells harboring IRF-inducible luciferase reporter construct assessed as increase in relative ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMedPDB3D3D Structure (crystal)