Compile Data Set for Download or QSAR
Report error Found 69 Enz. Inhib. hit(s) with all data for entry = 50015987
TargetLIM domain kinase 1(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50043510(CHEMBL3355507)
Affinity DataKd:  53nMAssay Description:Binding affinity to recombinant LIMK1 (330 to 637 residues) (unknown origin) expressed in baculovirus infected insect cells assessed as dissociation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 1(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591083(CHEMBL5184281)
Affinity DataKd:  89nMAssay Description:Binding affinity to recombinant LIMK1 (330 to 637 residues) (unknown origin) expressed in baculovirus infected insect cells assessed as dissociation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 1(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591084(CHEMBL5186508)
Affinity DataKd:  386nMAssay Description:Binding affinity to recombinant LIMK1 (330 to 637 residues) (unknown origin) expressed in baculovirus infected insect cells assessed as dissociation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 1(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591082(CHEMBL4790618)
Affinity DataKd:  64nMAssay Description:Binding affinity to recombinant LIMK1 (330 to 637 residues) (unknown origin) expressed in baculovirus infected insect cells assessed as dissociation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 2(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591082(CHEMBL4790618)
Affinity DataKd:  64nMAssay Description:Binding affinity to human wild-type full length LIMK2 (M1 to P638 residues) expressed in bacterial expression system assessed as dissociation constan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 1(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591082(CHEMBL4790618)
Affinity DataKd:  120nMAssay Description:Binding affinity to human wild-type full length LIMK1 (M1 to D647 residues) expressed in bacterial expression system assessed as dissociation constan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 2(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591090(CHEMBL2141887)
Affinity DataKd:  57nMAssay Description:Binding affinity to LIMK2 in human HeLa cells assessed as apparent dissociation constant incubated for 45 mins by kinobead based pulldown assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 2(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591091(CHEMBL5169387)
Affinity DataKd:  231nMAssay Description:Binding affinity to LIMK2 in human HeLa cells assessed as apparent dissociation constant incubated for 45 mins by kinobead based pulldown assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetLIM domain kinase 2(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591082(CHEMBL4790618)
Affinity DataKd:  1.66E+3nMAssay Description:Binding affinity to LIMK2 in human HeLa cells assessed as apparent dissociation constant incubated for 45 mins by kinobead based pulldown assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 1(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591090(CHEMBL2141887)
Affinity DataKd:  59nMAssay Description:Binding affinity to LIMK1 in human HeLa cells assessed as apparent dissociation constant incubated for 45 mins by kinobead based pulldown assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 1(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591091(CHEMBL5169387)
Affinity DataKd:  177nMAssay Description:Binding affinity to LIMK1 in human HeLa cells assessed as apparent dissociation constant incubated for 45 mins by kinobead based pulldown assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetLIM domain kinase 1(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591082(CHEMBL4790618)
Affinity DataKd:  682nMAssay Description:Binding affinity to LIMK1 in human HeLa cells assessed as apparent dissociation constant incubated for 45 mins by kinobead based pulldown assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 2(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50044004(CHEMBL3356433)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of LIMK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 1(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591090(CHEMBL2141887)
Affinity DataIC50: 7nMAssay Description:Inhibition of human glutathione S-transferase-tagged LIMK1 (321 to 647 residues) expressed in baculovirus-infected Sf9 cells incubated for 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 1(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591091(CHEMBL5169387)
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant LIMK1 (330 to 637 residues) (unknown origin) expressed in baculovirus infected insect cells using CFL1 as substrate preincu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetLIM domain kinase 2(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591090(CHEMBL2141887)
Affinity DataIC50: 8nMAssay Description:Inhibition of human glutathione S-transferase-tagged LIMK2 (312 to 638 residues) expressed in baculovirus-infected Sf9 cells incubated for 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 1(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591091(CHEMBL5169387)
Affinity DataIC50: 9.80nMAssay Description:Inhibition of recombinant full length LIMK1 (330 to 637 residues) (unknown origin) expressed in HEK293T cells incubated for 2 hrs in presence of trac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetLIM domain kinase 2(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591090(CHEMBL2141887)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant LIMK2 (330 to 632 residues) (unknown origin) expressed in baculovirus infected insect cells using CFL1 as substrate preincu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 2(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591091(CHEMBL5169387)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant full length LIMK2 (330 to 632 residues) (unknown origin) expressed in HEK293T cells incubated for 2 hrs in presence of trac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetLIM domain kinase 2(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591082(CHEMBL4790618)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant LIMK2 (330 to 632 residues) (unknown origin) expressed in baculovirus infected insect cells using CFL1 as substrate preincu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 1(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591090(CHEMBL2141887)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant LIMK1 (330 to 637 residues) (unknown origin) expressed in baculovirus infected insect cells using CFL1 as substrate preincu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 2(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591090(CHEMBL2141887)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant full length LIMK2 (330 to 632 residues) (unknown origin) expressed in HEK293T cells incubated for 2 hrs in presence of trac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 2(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591091(CHEMBL5169387)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant LIMK2 (330 to 632 residues) (unknown origin) expressed in baculovirus infected insect cells using CFL1 as substrate preincu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetLIM domain kinase 2(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50072664(CHEMBL3410036)
Affinity DataIC50: 24nMAssay Description:Inhibition of LIMK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 1(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50072664(CHEMBL3410036)
Affinity DataIC50: 43nMAssay Description:Inhibition of LIMK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 1(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591101(CHEMBL5209373)
Affinity DataIC50: 50nMAssay Description:Inhibition of GST tagged recombinant LIMK1 (unknown origin) using cofilin as substrate by by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 2(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591095(CHEMBL5181311)
Affinity DataIC50: 61nMAssay Description:Inhibition of recombinant full length LIMK2 (330 to 632 residues) (unknown origin) expressed in HEK293T cells incubated for 2 hrs in presence of trac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 1(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591090(CHEMBL2141887)
Affinity DataIC50: 62nMAssay Description:Inhibition of recombinant full length LIMK1 (330 to 637 residues) (unknown origin) expressed in HEK293T cells incubated for 2 hrs in presence of trac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 2(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591088(CHEMBL5206269)
Affinity DataIC50: 65nMAssay Description:Inhibition of recombinant full length LIMK2 (330 to 632 residues) (unknown origin) expressed in HEK293T cells incubated for 2 hrs in presence of trac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 1(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591088(CHEMBL5206269)
Affinity DataIC50: 65nMAssay Description:Inhibition of recombinant full length LIMK1 (330 to 637 residues) (unknown origin) expressed in HEK293T cells incubated for 2 hrs in presence of trac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 2(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591089(CHEMBL5190928)
Affinity DataIC50: 67nMAssay Description:Inhibition of recombinant full length LIMK2 (330 to 632 residues) (unknown origin) expressed in HEK293T cells incubated for 2 hrs in presence of trac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 2(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591101(CHEMBL5209373)
Affinity DataIC50: 75nMAssay Description:Inhibition of GST tagged recombinant LIMK2 (unknown origin) using cofilin as substrate by by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 1(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591082(CHEMBL4790618)
Affinity DataIC50: 84nMAssay Description:Inhibition of recombinant LIMK1 (330 to 637 residues) (unknown origin) expressed in baculovirus infected insect cells using CFL1 as substrate preincu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 2(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591093(CHEMBL5184302)
Affinity DataIC50: 87nMAssay Description:Inhibition of recombinant full length LIMK2 (330 to 632 residues) (unknown origin) expressed in HEK293T cells incubated for 2 hrs in presence of trac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 2(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591097(CHEMBL5184275)
Affinity DataIC50: 90nMAssay Description:Inhibition of recombinant full length LIMK2 (330 to 632 residues) (unknown origin) expressed in HEK293T cells incubated for 2 hrs in presence of trac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 2(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591082(CHEMBL4790618)
Affinity DataIC50: 91nMAssay Description:Inhibition of recombinant full length LIMK2 (330 to 632 residues) (unknown origin) expressed in HEK293T cells incubated for 2 hrs in presence of trac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 2(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591087(CHEMBL5179261)
Affinity DataIC50: 92nMAssay Description:Inhibition of recombinant full length LIMK2 (330 to 632 residues) (unknown origin) expressed in HEK293T cells incubated for 2 hrs in presence of trac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 1(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591095(CHEMBL5181311)
Affinity DataIC50: 117nMAssay Description:Inhibition of recombinant full length LIMK1 (330 to 637 residues) (unknown origin) expressed in HEK293T cells incubated for 2 hrs in presence of trac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 2(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591096(CHEMBL5190028)
Affinity DataIC50: 118nMAssay Description:Inhibition of recombinant full length LIMK2 (330 to 632 residues) (unknown origin) expressed in HEK293T cells incubated for 2 hrs in presence of trac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 2(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591094(CHEMBL5202731)
Affinity DataIC50: 121nMAssay Description:Inhibition of recombinant full length LIMK2 (330 to 632 residues) (unknown origin) expressed in HEK293T cells incubated for 2 hrs in presence of trac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 1(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591086(CHEMBL5192852)
Affinity DataIC50: 135nMAssay Description:Inhibition of recombinant full length LIMK1 (330 to 637 residues) (unknown origin) expressed in HEK293T cells incubated for 2 hrs in presence of trac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 1(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591089(CHEMBL5190928)
Affinity DataIC50: 158nMAssay Description:Inhibition of recombinant full length LIMK1 (330 to 637 residues) (unknown origin) expressed in HEK293T cells incubated for 2 hrs in presence of trac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 2(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591086(CHEMBL5192852)
Affinity DataIC50: 161nMAssay Description:Inhibition of recombinant full length LIMK2 (330 to 632 residues) (unknown origin) expressed in HEK293T cells incubated for 2 hrs in presence of trac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 1(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591090(CHEMBL2141887)
Affinity DataIC50: 179nMAssay Description:Inhibition of LIMK1 in human HeLa cells lysate incubated for 45 mins by kinobead based pulldown assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 1(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591093(CHEMBL5184302)
Affinity DataIC50: 186nMAssay Description:Inhibition of recombinant full length LIMK1 (330 to 637 residues) (unknown origin) expressed in HEK293T cells incubated for 2 hrs in presence of trac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 2(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591090(CHEMBL2141887)
Affinity DataIC50: 222nMAssay Description:Inhibition of LIMK2 in human HeLa cells lysate incubated for 45 mins by kinobead based pulldown assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 1(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591082(CHEMBL4790618)
Affinity DataIC50: 238nMAssay Description:Inhibition of recombinant full length LIMK1 (330 to 637 residues) (unknown origin) expressed in HEK293T cells incubated for 2 hrs in presence of trac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 1(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591091(CHEMBL5169387)
Affinity DataIC50: 249nMAssay Description:Inhibition of LIMK1 in human HeLa cells lysate incubated for 45 mins by kinobead based pulldown assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetLIM domain kinase 1(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591087(CHEMBL5179261)
Affinity DataIC50: 251nMAssay Description:Inhibition of recombinant full length LIMK1 (330 to 637 residues) (unknown origin) expressed in HEK293T cells incubated for 2 hrs in presence of trac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetLIM domain kinase 1(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50591097(CHEMBL5184275)
Affinity DataIC50: 305nMAssay Description:Inhibition of recombinant full length LIMK1 (330 to 637 residues) (unknown origin) expressed in HEK293T cells incubated for 2 hrs in presence of trac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
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