Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50017436
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50601896(CHEMBL5203781)
Affinity DataIC50: 4nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current amplitude at -80 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50601896(CHEMBL5203781)
Affinity DataIC50: 21nMAssay Description:Antagonist activity at human alpha3beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current amplitude at -80 mV ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50601894(CHEMBL5196098)
Affinity DataIC50: 92nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current amplitude at -80 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50601894(CHEMBL5196098)
Affinity DataIC50: 219nMAssay Description:Antagonist activity at human alpha3beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current amplitude at -80 mV ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50601896(CHEMBL5203781)
Affinity DataIC50: 259nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current amplitude at -80 mV holdi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50601896(CHEMBL5203781)
Affinity DataIC50: 266nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current amplitude at -80 mV holdi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50601895(CHEMBL5192422)
Affinity DataIC50: 500nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current amplitude at -80 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50445324(CHEMBL3104237)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current amplitude at -80 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed