Compile Data Set for Download or QSAR
Report error Found 60 Enz. Inhib. hit(s) with all data for entry = 50015817
TargetMatrilysin(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589859(CHEMBL5204457)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant MMP-7 (Leu18 to Lys267 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMatrilysin(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589860(CHEMBL5183142)
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant MMP-7 (Leu18 to Lys267 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMatrilysin(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589865(CHEMBL5169356)
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant MMP-7 (Leu18 to Lys267 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMatrilysin(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589866(CHEMBL5192674)
Affinity DataIC50: 56nMAssay Description:Inhibition of human recombinant MMP-7 (Leu18 to Lys267 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMatrilysin(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589869(CHEMBL5170327)
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant MMP-7 (Leu18 to Lys267 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMatrilysin(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589870(CHEMBL5202455)
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant MMP-7 (Leu18 to Lys267 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMatrilysin(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589873(CHEMBL5188110)
Affinity DataIC50: 440nMAssay Description:Inhibition of human recombinant MMP-7 (Leu18 to Lys267 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMatrix metalloproteinase-14(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589859(CHEMBL5204457)
Affinity DataIC50: 450nMAssay Description:Inhibition of human recombinant C-terminal 10-His tagged MMP-14 ( Ala21 to Gly284 residues) using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMatrilysin(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589863(CHEMBL5184919)
Affinity DataIC50: 780nMAssay Description:Inhibition of human recombinant MMP-7 (Leu18 to Lys267 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMatrilysin(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589872(CHEMBL5170295)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant MMP-7 (Leu18 to Lys267 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMatrilysin(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589868(CHEMBL5194462)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human recombinant MMP-7 (Leu18 to Lys267 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMacrophage metalloelastase(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589859(CHEMBL5204457)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human recombinant MMP-12 (Leu17 to Cys470 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMatrilysin(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589864(CHEMBL5173295)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of human recombinant MMP-7 (Leu18 to Lys267 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMatrilysin(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589867(CHEMBL5189261)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of human recombinant MMP-7 (Leu18 to Lys267 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMatrilysin(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589862(CHEMBL5186294)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of human recombinant MMP-7 (Leu18 to Lys267 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMatrilysin(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589871(CHEMBL5185905)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of human recombinant MMP-7 (Leu18 to Lys267 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMatrilysin(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589861(CHEMBL5196897)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of human recombinant MMP-7 (Leu18 to Lys267 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMatrix metalloproteinase-14(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589860(CHEMBL5183142)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human recombinant C-terminal 10-His tagged MMP-14 ( Ala21 to Gly284 residues) using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589859(CHEMBL5204457)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human recombinant MMP-2 ( Ile34 to Cys660 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMacrophage metalloelastase(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589860(CHEMBL5183142)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human recombinant MMP-12 (Leu17 to Cys470 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMatrix metalloproteinase-14(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589866(CHEMBL5192674)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human recombinant C-terminal 10-His tagged MMP-14 ( Ala21 to Gly284 residues) using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMacrophage metalloelastase(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589870(CHEMBL5202455)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant MMP-12 (Leu17 to Cys470 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMatrix metalloproteinase-14(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589870(CHEMBL5202455)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant C-terminal 10-His tagged MMP-14 ( Ala21 to Gly284 residues) using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMacrophage metalloelastase(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589866(CHEMBL5192674)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of human recombinant MMP-12 (Leu17 to Cys470 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589860(CHEMBL5183142)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human recombinant MMP-2 ( Ile34 to Cys660 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMacrophage metalloelastase(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589873(CHEMBL5188110)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant MMP-12 (Leu17 to Cys470 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589866(CHEMBL5192674)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of human recombinant MMP-2 ( Ile34 to Cys660 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetNeutrophil collagenase(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589859(CHEMBL5204457)
Affinity DataIC50: 5.90E+4nMAssay Description:Inhibition of human recombinant MMP-8 (Phe21 to Gly467 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589870(CHEMBL5202455)
Affinity DataIC50: 7.30E+4nMAssay Description:Inhibition of human recombinant MMP-2 ( Ile34 to Cys660 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCollagenase 3(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589860(CHEMBL5183142)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MMP-13 (Leu20 to Cys471 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCollagenase 3(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589870(CHEMBL5202455)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MMP-13 (Leu20 to Cys471 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCollagenase 3(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589866(CHEMBL5192674)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MMP-13 (Leu20 to Cys471 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCollagenase 3(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589873(CHEMBL5188110)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MMP-13 (Leu20 to Cys471 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCollagenase 3(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589862(CHEMBL5186294)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MMP-13 (Leu20 to Cys471 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMatrix metalloproteinase-14(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589873(CHEMBL5188110)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant C-terminal 10-His tagged MMP-14 ( Ala21 to Gly284 residues) using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMatrix metalloproteinase-14(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589862(CHEMBL5186294)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant C-terminal 10-His tagged MMP-14 ( Ala21 to Gly284 residues) using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetNeutrophil collagenase(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589862(CHEMBL5186294)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MMP-8 (Phe21 to Gly467 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589859(CHEMBL5204457)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MMP-9 (Ala20 to Asp707 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetNeutrophil collagenase(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589860(CHEMBL5183142)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MMP-8 (Phe21 to Gly467 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589866(CHEMBL5192674)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MMP-9 (Ala20 to Asp707 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589860(CHEMBL5183142)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MMP-9 (Ala20 to Asp707 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589873(CHEMBL5188110)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MMP-9 (Ala20 to Asp707 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589870(CHEMBL5202455)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MMP-9 (Ala20 to Asp707 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589862(CHEMBL5186294)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MMP-9 (Ala20 to Asp707 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCollagenase 3(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589859(CHEMBL5204457)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MMP-13 (Leu20 to Cys471 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMacrophage metalloelastase(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589862(CHEMBL5186294)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MMP-12 (Leu17 to Cys470 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589862(CHEMBL5186294)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MMP-2 ( Ile34 to Cys660 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589873(CHEMBL5188110)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MMP-2 ( Ile34 to Cys660 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetInterstitial collagenase(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589862(CHEMBL5186294)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MMP-1 (Phe20 to Asn469 residue) using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetInterstitial collagenase(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50589860(CHEMBL5183142)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MMP-1 (Phe20 to Asn469 residue) using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
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