Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50018016
TargetTriple specificity protein phosphatase PtpB(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Peking Union Medical College and Chinese Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis H37Rv MptpB using pNPP as substrate incubated for 10 mins and measured by spectrophotometric met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTriple specificity protein phosphatase PtpB(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Peking Union Medical College and Chinese Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50606977(CHEMBL3769851)
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis H37Rv MptpB using pNPP as substrate incubated for 10 mins and measured by spectrophotometric met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTriple specificity protein phosphatase PtpB(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Peking Union Medical College and Chinese Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50425807(CHEMBL2316902)
Affinity DataIC50: 38nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis H37Rv MptpB using pNPP as substrate incubated for 10 mins and measured by spectrophotometric met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTriple specificity protein phosphatase PtpB(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Peking Union Medical College and Chinese Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50606980(CHEMBL5220804)
Affinity DataKi:  1.01E+3nMAssay Description:Non-competitive inhibition of recombinant Mycobacterium tuberculosis H37Rv MptpB using pNPP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTriple specificity protein phosphatase PtpB(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Peking Union Medical College and Chinese Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50606976(CHEMBL5218633)
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis H37Rv MptpB using pNPP as substrate incubated for 10 mins and measured by spectrophotometric met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTriple specificity protein phosphatase PtpB(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Peking Union Medical College and Chinese Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50606980(CHEMBL5220804)
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis H37Rv MptpB using pNPP as substrate incubated for 10 mins and measured by spectrophotometric met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTriple specificity protein phosphatase PtpB(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Peking Union Medical College and Chinese Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50604332(CHEMBL4214022)
Affinity DataIC50: 2.98E+3nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis H37Rv MptpB using pNPP as substrate incubated for 10 mins and measured by spectrophotometric met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Peking Union Medical College and Chinese Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50606985(CHEMBL5220318)
Affinity DataIC50: 3.43E+3nMAssay Description:Inhibition of recombinant human PTP1B using pNPP as substrate preincubated for 5 mins followed by substrate addition assessed as reduction in p-nitro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTriple specificity protein phosphatase PtpB(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Peking Union Medical College and Chinese Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50606986(CHEMBL5218779)
Affinity DataIC50: 3.62E+3nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis H37Rv MptpB using pNPP as substrate incubated for 10 mins and measured by spectrophotometric met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTriple specificity protein phosphatase PtpB(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Peking Union Medical College and Chinese Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50606981(CHEMBL5220330)
Affinity DataIC50: 3.81E+3nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis H37Rv MptpB using pNPP as substrate incubated for 10 mins and measured by spectrophotometric met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTriple specificity protein phosphatase PtpB(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Peking Union Medical College and Chinese Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50606979(CHEMBL5219572)
Affinity DataIC50: 3.82E+3nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis H37Rv MptpB using pNPP as substrate incubated for 10 mins and measured by spectrophotometric met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Peking Union Medical College and Chinese Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50606979(CHEMBL5219572)
Affinity DataIC50: 3.93E+3nMAssay Description:Inhibition of recombinant human PTP1B using pNPP as substrate preincubated for 5 mins followed by substrate addition assessed as reduction in p-nitro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTriple specificity protein phosphatase PtpB(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Peking Union Medical College and Chinese Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50606984(CHEMBL5220182)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis H37Rv MptpB using pNPP as substrate incubated for 10 mins and measured by spectrophotometric met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Peking Union Medical College and Chinese Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50606980(CHEMBL5220804)
Affinity DataIC50: 5.16E+3nMAssay Description:Inhibition of recombinant human PTP1B using pNPP as substrate preincubated for 5 mins followed by substrate addition assessed as reduction in p-nitro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTriple specificity protein phosphatase PtpB(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Peking Union Medical College and Chinese Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50606982(CHEMBL5220490)
Affinity DataIC50: 5.32E+3nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis H37Rv MptpB using pNPP as substrate incubated for 10 mins and measured by spectrophotometric met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTriple specificity protein phosphatase PtpB(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Peking Union Medical College and Chinese Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50606985(CHEMBL5220318)
Affinity DataIC50: 5.95E+3nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis H37Rv MptpB using pNPP as substrate incubated for 10 mins and measured by spectrophotometric met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Peking Union Medical College and Chinese Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50606982(CHEMBL5220490)
Affinity DataIC50: 6.28E+3nMAssay Description:Inhibition of recombinant human PTP1B using pNPP as substrate preincubated for 5 mins followed by substrate addition assessed as reduction in p-nitro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Peking Union Medical College and Chinese Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50606984(CHEMBL5220182)
Affinity DataIC50: 7.81E+3nMAssay Description:Inhibition of recombinant human PTP1B using pNPP as substrate preincubated for 5 mins followed by substrate addition assessed as reduction in p-nitro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Peking Union Medical College and Chinese Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50606980(CHEMBL5220804)
Affinity DataIC50: 8.97E+3nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis H37Rv MptpA using pNPP as substrate incubated for 10 mins and measured by spectrophotometric met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTriple specificity protein phosphatase PtpB(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Peking Union Medical College and Chinese Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50606983(CHEMBL5220166)
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis H37Rv MptpB using pNPP as substrate incubated for 10 mins and measured by spectrophotometric met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Peking Union Medical College and Chinese Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50606979(CHEMBL5219572)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis H37Rv MptpA using pNPP as substrate incubated for 10 mins and measured by spectrophotometric met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTriple specificity protein phosphatase PtpB(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Peking Union Medical College and Chinese Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50606978(CHEMBL5220755)
Affinity DataIC50: 2.24E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis H37Rv MptpB using pNPP as substrate incubated for 10 mins and measured by spectrophotometric met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Peking Union Medical College and Chinese Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50606981(CHEMBL5220330)
Affinity DataIC50: 2.73E+4nMAssay Description:Inhibition of recombinant human PTP1B using pNPP as substrate preincubated for 5 mins followed by substrate addition assessed as reduction in p-nitro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Peking Union Medical College and Chinese Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50606986(CHEMBL5218779)
Affinity DataIC50: 3.41E+4nMAssay Description:Inhibition of recombinant human PTP1B using pNPP as substrate preincubated for 5 mins followed by substrate addition assessed as reduction in p-nitro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed