Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 50019943
TargetNonstructural protein 3(ZIKV)
Macao University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50624873(CHEMBL5410367)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant ZIKV NS2B-NS3 protease using Bz-Nle-K-K-R-AMC as substrate incubated for 1 hr by fluorescence-based microplate reader assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Macao University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50182488(CHEMBL3819036)
Affinity DataIC50: 7.55E+3nMAssay Description:Inhibition of DENV2 NS2B/NS3 protease using Boc-Gly-Arg-Arg-MCA as substrate preincubated for 10 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Macao University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM15236(CHEMBL164 | Cannabiscetin | 3,5,7-trihydroxy-2-(3,...)
Affinity DataIC50: 8.46E+3nMAssay Description:Inhibition of DENV2 NS2B (48 to 100 residues)/NS3 (14 to 185 residues) protease expressed in Escherichia coli BL21 (DE3) using Bz-Nle-Lys-Arg-Arg-AMC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed