Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50017440
TargetMitogen-activated protein kinase 1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50094465(CHEMBL3590106 | US10525036, Example BVD-523 | US10...)
Affinity DataKi:  0.0400nMAssay Description:Binding affinity to ERK2 (unknown origin) measured after 20 mins in presence of [gamma33P]ATP by scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase 1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50601918(TEMUTERKIB | Temuterkib | Ly 3214996 | Ly3214996 |...)
Affinity DataKi:  0.0640nMAssay Description:Binding affinity to ERK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50094465(CHEMBL3590106 | US10525036, Example BVD-523 | US10...)
Affinity DataKi: <0.300nMAssay Description:Binding affinity to ERK1 (unknown origin) measured after 20 mins in presence of [gamma33P]ATP by scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50601918(TEMUTERKIB | Temuterkib | Ly 3214996 | Ly3214996 |...)
Affinity DataKi:  0.650nMAssay Description:Binding affinity to ERK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase 1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50094464(CHEMBL3590107 | US10525036, Example SCH772984 | US...)
Affinity DataIC50: 1nMAssay Description:Inhibition of ERK2 (unknown origin) incubated for 45 mins in presence of ATP by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase 1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50601920(Asn007 | Asn007 rd | ASN007)
Affinity DataIC50: 2nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50601920(Asn007 | Asn007 rd | ASN007)
Affinity DataIC50: 2nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50094464(CHEMBL3590107 | US10525036, Example SCH772984 | US...)
Affinity DataIC50: 4nMAssay Description:Inhibition of ERK1 (unknown origin) incubated for 45 mins in presence of ATP by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase 1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50601918(TEMUTERKIB | Temuterkib | Ly 3214996 | Ly3214996 |...)
Affinity DataIC50: 5nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50601918(TEMUTERKIB | Temuterkib | Ly 3214996 | Ly3214996 |...)
Affinity DataIC50: 5nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase 1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM351000(US9796700, Compound I-90)
Affinity DataIC50: 10nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase 1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM318045(US9624228, Example 1 | US10301317, Example 1)
Affinity DataIC50: 10nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM351000(US9796700, Compound I-90)
Affinity DataIC50: 10nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM318045(US9624228, Example 1 | US10301317, Example 1)
Affinity DataIC50: 10nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase 1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50601917(CHEMBL5180873)
Affinity DataKd:  380nMAssay Description:Binding affinity to ERK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase 1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50601919(CHEMBL5180742)
Affinity DataIC50: 500nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase 1(Rat)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50526695(CHEMBL508280 | BI-78D3)
Affinity DataKi:  2.30E+3nMAssay Description:Binding affinity to rat full-length ERK2 using FQRKTLQRRNLKGLNLNL-XXX-TGPLSPGPF peptide as substrate in presence of [gamma33P]ATP by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase 1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50601917(CHEMBL5180873)
Affinity DataIC50: 9.90E+3nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed