Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50016008
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
University of Bayreuth

Curated by ChEMBL
LigandPNGBDBM50591387(CHEMBL5171546)
Affinity DataKd:  2.40E+4nMAssay Description:Binding affinity to N-terminal his-tagged human SIRT5 (34 to 302 residues) expressed in Escherichia coli assessed as dissociation constant using CPS1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
University of Bayreuth

Curated by ChEMBL
LigandPNGBDBM50591386(CHEMBL5171187)
Affinity DataKd:  2.80E+4nMAssay Description:Binding affinity to N-terminal his-tagged human SIRT5 (34 to 302 residues) expressed in Escherichia coli assessed as dissociation constant by microsc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
University of Bayreuth

Curated by ChEMBL
LigandPNGBDBM50591387(CHEMBL5171546)
Affinity DataKd:  2.80E+4nMAssay Description:Binding affinity to N-terminal his-tagged human SIRT5 (34 to 302 residues) expressed in Escherichia coli assessed as dissociation constant using NAD+...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
University of Bayreuth

Curated by ChEMBL
LigandPNGBDBM50591387(CHEMBL5171546)
Affinity DataKd:  3.20E+4nMAssay Description:Binding affinity to N-terminal his-tagged human SIRT3 (114 to 380 residues) expressed in Escherichia coli assessed as dissociation constant by micros...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
University of Bayreuth

Curated by ChEMBL
LigandPNGBDBM50591386(CHEMBL5171187)
Affinity DataEC50:  4.00E+4nMAssay Description:Activation of N-terminal his-tagged human SIRT5 (34 to 302 residues) expressed in Escherichia coli assessed as fold activation using CPS1-succ537 as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
University of Bayreuth

Curated by ChEMBL
LigandPNGBDBM50591387(CHEMBL5171546)
Affinity DataKd:  8.30E+4nMAssay Description:Binding affinity to N-terminal his-tagged human SIRT5 (34 to 302 residues) expressed in Escherichia coli assessed as dissociation constant by microsc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
University of Bayreuth

Curated by ChEMBL
LigandPNGBDBM50591386(CHEMBL5171187)
Affinity DataEC50:  1.00E+5nMAssay Description:Activation of N-terminal his-tagged human SIRT3 (114 to 380 residues) expressed in Escherichia coli in presence of NAD+ by Mass spectrometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
University of Bayreuth

Curated by ChEMBL
LigandPNGBDBM50591386(CHEMBL5171187)
Affinity DataKd:  1.38E+5nMAssay Description:Binding affinity to N-terminal his-tagged human SIRT3 (114 to 380 residues) expressed in Escherichia coli assessed as dissociation constant by micros...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed