Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50018800
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50612688(CHEMBL509307 | Indolo[3,2-B]Carbazole)
Affinity DataKd:  190nMAssay Description:Binding affinity to AhR (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50239186(CHEBI:50182 | 1,1-Bis(3''-Indolyl)Methane | 3,3''-...)
Affinity DataEC50:  7.80E+4nMAssay Description:Modulator activity at AhR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50506038(CHEMBL4580482)
Affinity DataEC50:  49nMAssay Description:Modulator activity at AhR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM23927(Tetrachlorodibenzodioxin | 2,3,7,8-Tetrachlorodibe...)
Affinity DataEC50:  9nMAssay Description:Activation of human AhR expressed in Saccharomyces cerevisiae YCM3 coexpressing ARNT incubated for 18 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50310357(indigo | CHEMBL599552)
Affinity DataEC50:  5nMAssay Description:Activation of human AhR expressed in Saccharomyces cerevisiae YCM3 coexpressing ARNT incubated for 18 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM7392(2-[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]-2,3-...)
Affinity DataEC50:  0.200nMAssay Description:Activation of human AhR expressed in Saccharomyces cerevisiae YCM3 coexpressing ARNT incubated for 18 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50612691(PROCHLORAZ | CHEBI:8434 | Prochloraz)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at AhR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50605060(CHEMBL5198290 | US11891386, Compound 004)
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at AhR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50603549(CHEMBL5203882)
Affinity DataEC50:  0.0300nMAssay Description:Agonist activity at AhR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50563366(CHEMBL4764225)
Affinity DataEC50:  2.5nMAssay Description:Agonist activity at AhR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50612690(CHEMBL5267667)
Affinity DataEC50:  12nMAssay Description:Agonist activity at AhR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50612689(CHEMBL5289699)
Affinity DataEC50:  10nMAssay Description:Agonist activity at AhR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50239186(CHEBI:50182 | 1,1-Bis(3''-Indolyl)Methane | 3,3''-...)
Affinity DataKd:  90nMAssay Description:Binding affinity to AhR (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50506038(CHEMBL4580482)
Affinity DataKd:  0.130nMAssay Description:Binding affinity to AhR (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50563365(CHEMBL4750416)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at AhR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50541262(6-Formylindolo[3,2-B]Carbazole | CHEMBL472031)
Affinity DataKd:  70nMAssay Description:Binding affinity to AhR (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50519636(BMN 195 | BMN-195 | Ezutromid | SMT-C1100 | SMTC-1...)
Affinity DataKd:  50nMAssay Description:Binding affinity to AhR (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50612694(CHEMBL5281742)
Affinity DataIC50: 0.885nMAssay Description:Antagonist activity at AhR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50525572(CHEMBL1743245 | CH-223191)
Affinity DataIC50: 30nMAssay Description:Antagonist activity at AhR (unknown origin) assessed as inhibition of TCDD-induced luciferase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50612692(CHEMBL5266911)
Affinity DataIC50: 40nMAssay Description:Antagonist activity at AhR (unknown origin) expressed in human U87 cells assessed as inhibition of kynurenic acid-induced transactivation by Renilla/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50612695(CHEMBL5271453)
Affinity DataIC50: 82nMAssay Description:Antagonist activity at AhR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50612699(CHEMBL4303221)
Affinity DataIC50: 127nMAssay Description:Antagonist activity at AhR in human HepG2 cells assessed as inhibition of TCDD-induced receptor activation pretreated for 1 hr followed by TCDD addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50612696(CHEMBL5280174)
Affinity DataIC50: 500nMAssay Description:Antagonist activity at AhR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50612693(CHEMBL5267451)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at AhR in rat liver cytosol assessed as inhibition of TCDD-induced AhR/DNA complex formation by gel retardation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50612693(CHEMBL5267451)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of TCDD binding to rat liver cytosol AhRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50612697(CHEMBL3252119)
Affinity DataIC50: 1.10E+4nMAssay Description:Antagonist activity at AhR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50612698(CHEMBL5287208)
Affinity DataIC50: 1.20E+4nMAssay Description:Antagonist activity at AhR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM23936(1,3-dichloro-5-[(E)-2-[4-(trifluoromethyl)phenyl]e...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity to AhR (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50605060(CHEMBL5198290 | US11891386, Compound 004)
Affinity DataKi:  88nMAssay Description:Binding affinity to AhR (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed