Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50018802
TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50612741(CHEMBL5280471)
Affinity DataIC50: 7nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system measured after 2 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50185140(AP-26113 | Brigatinib | US11248003, Example Brigat...)
Affinity DataIC50: 8nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system measured after 2 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50612743(CHEMBL5290340)
Affinity DataIC50: 20nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system measured after 2 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50612742(CHEMBL5284179)
Affinity DataIC50: 22nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system measured after 2 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50612746(CHEMBL5284866)
Affinity DataIC50: 32nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system measured after 2 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50612738(CHEMBL5271155)
Affinity DataIC50: 34nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system measured after 2 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50612747(CHEMBL5273000)
Affinity DataIC50: 36nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system measured after 2 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50612744(CHEMBL5279933)
Affinity DataIC50: 41nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system measured after 2 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50612736(CHEMBL5268092)
Affinity DataIC50: 47nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system measured after 2 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50612740(CHEMBL5275486)
Affinity DataIC50: 107nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system measured after 2 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50612727(CHEMBL5284848)
Affinity DataIC50: 128nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system measured after 2 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50612728(CHEMBL5271568)
Affinity DataIC50: 142nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system measured after 2 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50612745(CHEMBL5268062)
Affinity DataIC50: 160nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system measured after 2 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50612753(CHEMBL5265927)
Affinity DataIC50: 230nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system measured after 2 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50612751(CHEMBL5280292)
Affinity DataIC50: 337nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system measured after 2 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50612749(CHEMBL5273342)
Affinity DataIC50: 352nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system measured after 2 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50595124(VANDETANIB | CHEBI:49960 | Vandetanib | GNF-PF-218...)
Affinity DataIC50: 369nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system measured after 2 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50095227((6,7-Dimethoxy-quinazolin-4-yl)-(4-phenoxy-phenyl)...)
Affinity DataIC50: 373nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system measured after 2 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50612730(CHEMBL5289352)
Affinity DataIC50: 550nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system measured after 2 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50612724(CHEMBL5288957)
Affinity DataIC50: 609nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system measured after 2 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50612725(CHEMBL5274670)
Affinity DataIC50: 672nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system measured after 2 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50612729(CHEMBL5281945)
Affinity DataIC50: 679nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system measured after 2 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50612731(CHEMBL5280288)
Affinity DataIC50: 712nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system measured after 2 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50612748(CHEMBL5290879)
Affinity DataIC50: 729nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system measured after 2 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50612750(CHEMBL5280575)
Affinity DataIC50: 891nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system measured after 2 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50612737(CHEMBL5290503)
Affinity DataIC50: 952nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system measured after 2 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50612752(CHEMBL5273994)
Affinity DataIC50: 3.75E+3nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system measured after 2 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50612732(CHEMBL5289511)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system measured after 2 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50612733(CHEMBL5266759)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system measured after 2 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50612734(CHEMBL5282516)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system measured after 2 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50612739(CHEMBL5273819)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system measured after 2 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50612726(CHEMBL5267136)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system measured after 2 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50612735(CHEMBL5281434)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system measured after 2 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50612754(CHEMBL5267362)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system measured after 2 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50612755(CHEMBL5277339)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system measured after 2 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50612756(CHEMBL5283714)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system measured after 2 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50612757(CHEMBL5267924)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system measured after 2 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50612758(CHEMBL5270822)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) expressed in Bac-to-Bac baculovirus expression system measured after 2 hrs by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed