Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50017448
TargetP2X purinoceptor 7(Human)
Takasaki University of Health and Welfare

Curated by ChEMBL
LigandPNGBDBM50601963(CHEMBL5171135)
Affinity DataIC50: 110nMAssay Description:Antagonist activity at P2X7 receptor in human RPMI-8226 cells assessed as inhibition of ATP-induced Ca2+ influx by fura-2 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Takasaki University of Health and Welfare

Curated by ChEMBL
LigandPNGBDBM50601962(CHEMBL5201862)
Affinity DataIC50: 120nMAssay Description:Antagonist activity at P2X7 receptor in human RPMI-8226 cells assessed as inhibition of ATP-induced Ca2+ influx by fura-2 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Takasaki University of Health and Welfare

Curated by ChEMBL
LigandPNGBDBM50601949(CHEMBL5195646)
Affinity DataIC50: 120nMAssay Description:Antagonist activity at P2X7 receptor in human RPMI-8226 cells assessed as inhibition of ATP-induced Ca2+ influx by fura-2 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Takasaki University of Health and Welfare

Curated by ChEMBL
LigandPNGBDBM50601964(CHEMBL5182908)
Affinity DataIC50: 130nMAssay Description:Antagonist activity at P2X7 receptor in human RPMI-8226 cells assessed as inhibition of ATP-induced Ca2+ influx by fura-2 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Takasaki University of Health and Welfare

Curated by ChEMBL
LigandPNGBDBM50601961(CHEMBL5171001)
Affinity DataIC50: 150nMAssay Description:Antagonist activity at P2X7 receptor in human RPMI-8226 cells assessed as inhibition of ATP-induced Ca2+ influx by fura-2 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Takasaki University of Health and Welfare

Curated by ChEMBL
LigandPNGBDBM50601947(CHEMBL5200700)
Affinity DataIC50: 180nMAssay Description:Antagonist activity at P2X7 receptor in human RPMI-8226 cells assessed as inhibition of ATP-induced Ca2+ influx by fura-2 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Takasaki University of Health and Welfare

Curated by ChEMBL
LigandPNGBDBM50601936(CHEMBL5177748)
Affinity DataIC50: 180nMAssay Description:Antagonist activity at P2X7 receptor in human RPMI-8226 cells assessed as inhibition of ATP-induced Ca2+ influx by fura-2 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Takasaki University of Health and Welfare

Curated by ChEMBL
LigandPNGBDBM50601939(CHEMBL5171280)
Affinity DataIC50: 180nMAssay Description:Antagonist activity at P2X7 receptor in human RPMI-8226 cells assessed as inhibition of ATP-induced Ca2+ influx by fura-2 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Takasaki University of Health and Welfare

Curated by ChEMBL
LigandPNGBDBM50601943(CHEMBL5194286)
Affinity DataIC50: 190nMAssay Description:Antagonist activity at P2X7 receptor in human RPMI-8226 cells assessed as inhibition of ATP-induced Ca2+ influx by fura-2 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Takasaki University of Health and Welfare

Curated by ChEMBL
LigandPNGBDBM50601946(CHEMBL5197182)
Affinity DataIC50: 240nMAssay Description:Antagonist activity at P2X7 receptor in human RPMI-8226 cells assessed as inhibition of ATP-induced Ca2+ influx by fura-2 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Takasaki University of Health and Welfare

Curated by ChEMBL
LigandPNGBDBM50601944(CHEMBL5204877)
Affinity DataIC50: 320nMAssay Description:Antagonist activity at P2X7 receptor in human RPMI-8226 cells assessed as inhibition of ATP-induced Ca2+ influx by fura-2 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Takasaki University of Health and Welfare

Curated by ChEMBL
LigandPNGBDBM50601945(CHEMBL5181870)
Affinity DataIC50: 460nMAssay Description:Antagonist activity at P2X7 receptor in human RPMI-8226 cells assessed as inhibition of ATP-induced Ca2+ influx by fura-2 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Takasaki University of Health and Welfare

Curated by ChEMBL
LigandPNGBDBM50601948(CHEMBL5198192)
Affinity DataIC50: 480nMAssay Description:Antagonist activity at P2X7 receptor in human RPMI-8226 cells assessed as inhibition of ATP-induced Ca2+ influx by fura-2 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Takasaki University of Health and Welfare

Curated by ChEMBL
LigandPNGBDBM50601937(CHEMBL5181257)
Affinity DataIC50: 560nMAssay Description:Antagonist activity at P2X7 receptor in human RPMI-8226 cells assessed as inhibition of ATP-induced Ca2+ influx by fura-2 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Takasaki University of Health and Welfare

Curated by ChEMBL
LigandPNGBDBM50601942(CHEMBL5208688)
Affinity DataIC50: 770nMAssay Description:Antagonist activity at P2X7 receptor in human RPMI-8226 cells assessed as inhibition of ATP-induced Ca2+ influx by fura-2 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Takasaki University of Health and Welfare

Curated by ChEMBL
LigandPNGBDBM76863(MLS000028549 | OXATOMIDE | 3-[3-[4-(diphenylmethyl...)
Affinity DataIC50: 830nMAssay Description:Antagonist activity at P2X7 receptor in human RPMI-8226 cells assessed as inhibition of ATP-induced Ca2+ influx by fura-2 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Takasaki University of Health and Welfare

Curated by ChEMBL
LigandPNGBDBM50601940(CHEMBL5184536)
Affinity DataIC50: 850nMAssay Description:Antagonist activity at P2X7 receptor in human RPMI-8226 cells assessed as inhibition of ATP-induced Ca2+ influx by fura-2 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Takasaki University of Health and Welfare

Curated by ChEMBL
LigandPNGBDBM50601935(CHEMBL5192745)
Affinity DataIC50: 950nMAssay Description:Antagonist activity at P2X7 receptor in human RPMI-8226 cells assessed as inhibition of ATP-induced Ca2+ influx by fura-2 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Takasaki University of Health and Welfare

Curated by ChEMBL
LigandPNGBDBM50601941(CHEMBL5208637)
Affinity DataIC50: 1.20E+3nMAssay Description:Antagonist activity at P2X7 receptor in human RPMI-8226 cells assessed as inhibition of ATP-induced Ca2+ influx by fura-2 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Takasaki University of Health and Welfare

Curated by ChEMBL
LigandPNGBDBM50601958(CHEMBL5182856)
Affinity DataIC50: 1.50E+3nMAssay Description:Antagonist activity at P2X7 receptor in human RPMI-8226 cells assessed as inhibition of ATP-induced Ca2+ influx by fura-2 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Takasaki University of Health and Welfare

Curated by ChEMBL
LigandPNGBDBM50601956(CHEMBL5180281)
Affinity DataIC50: 2.30E+3nMAssay Description:Antagonist activity at P2X7 receptor in human RPMI-8226 cells assessed as inhibition of ATP-induced Ca2+ influx by fura-2 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Takasaki University of Health and Welfare

Curated by ChEMBL
LigandPNGBDBM50601934(CHEMBL5191786)
Affinity DataIC50: 2.40E+3nMAssay Description:Antagonist activity at P2X7 receptor in human RPMI-8226 cells assessed as inhibition of ATP-induced Ca2+ influx by fura-2 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Takasaki University of Health and Welfare

Curated by ChEMBL
LigandPNGBDBM50601952(CHEMBL5194571)
Affinity DataIC50: 3.20E+3nMAssay Description:Antagonist activity at P2X7 receptor in human RPMI-8226 cells assessed as inhibition of ATP-induced Ca2+ influx by fura-2 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Takasaki University of Health and Welfare

Curated by ChEMBL
LigandPNGBDBM50601953(CHEMBL5202834)
Affinity DataIC50: 3.40E+3nMAssay Description:Antagonist activity at P2X7 receptor in human RPMI-8226 cells assessed as inhibition of ATP-induced Ca2+ influx by fura-2 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Takasaki University of Health and Welfare

Curated by ChEMBL
LigandPNGBDBM50601959(CHEMBL5175346)
Affinity DataIC50: 3.80E+3nMAssay Description:Antagonist activity at P2X7 receptor in human RPMI-8226 cells assessed as inhibition of ATP-induced Ca2+ influx by fura-2 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Takasaki University of Health and Welfare

Curated by ChEMBL
LigandPNGBDBM50601951(CHEMBL5208657)
Affinity DataIC50: 4.50E+3nMAssay Description:Antagonist activity at P2X7 receptor in human RPMI-8226 cells assessed as inhibition of ATP-induced Ca2+ influx by fura-2 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Takasaki University of Health and Welfare

Curated by ChEMBL
LigandPNGBDBM50601932(CHEMBL5201680)
Affinity DataIC50: 5.20E+3nMAssay Description:Antagonist activity at P2X7 receptor in human RPMI-8226 cells assessed as inhibition of ATP-induced Ca2+ influx by fura-2 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Takasaki University of Health and Welfare

Curated by ChEMBL
LigandPNGBDBM50601954(CHEMBL5175342)
Affinity DataIC50: 5.30E+3nMAssay Description:Antagonist activity at P2X7 receptor in human RPMI-8226 cells assessed as inhibition of ATP-induced Ca2+ influx by fura-2 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Takasaki University of Health and Welfare

Curated by ChEMBL
LigandPNGBDBM50601955(CHEMBL5207374)
Affinity DataIC50: 6.50E+3nMAssay Description:Antagonist activity at P2X7 receptor in human RPMI-8226 cells assessed as inhibition of ATP-induced Ca2+ influx by fura-2 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Takasaki University of Health and Welfare

Curated by ChEMBL
LigandPNGBDBM50601933(CHEMBL5174464)
Affinity DataIC50: 7.50E+3nMAssay Description:Antagonist activity at P2X7 receptor in human RPMI-8226 cells assessed as inhibition of ATP-induced Ca2+ influx by fura-2 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Takasaki University of Health and Welfare

Curated by ChEMBL
LigandPNGBDBM50601928(CHEMBL5182172)
Affinity DataIC50: 7.80E+3nMAssay Description:Antagonist activity at P2X7 receptor in human RPMI-8226 cells assessed as inhibition of ATP-induced Ca2+ influx by fura-2 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Takasaki University of Health and Welfare

Curated by ChEMBL
LigandPNGBDBM50601957(CHEMBL5197076)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at P2X7 receptor in human RPMI-8226 cells assessed as inhibition of ATP-induced Ca2+ influx by fura-2 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Takasaki University of Health and Welfare

Curated by ChEMBL
LigandPNGBDBM50601960(CHEMBL5181046)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at P2X7 receptor in human RPMI-8226 cells assessed as inhibition of ATP-induced Ca2+ influx by fura-2 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Takasaki University of Health and Welfare

Curated by ChEMBL
LigandPNGBDBM50601930(CHEMBL5193421)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at P2X7 receptor in human RPMI-8226 cells assessed as inhibition of ATP-induced Ca2+ influx by fura-2 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Takasaki University of Health and Welfare

Curated by ChEMBL
LigandPNGBDBM50601929(CHEMBL5189186)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at P2X7 receptor in human RPMI-8226 cells assessed as inhibition of ATP-induced Ca2+ influx by fura-2 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Takasaki University of Health and Welfare

Curated by ChEMBL
LigandPNGBDBM50601931(CHEMBL5202096)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at P2X7 receptor in human RPMI-8226 cells assessed as inhibition of ATP-induced Ca2+ influx by fura-2 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Takasaki University of Health and Welfare

Curated by ChEMBL
LigandPNGBDBM50601950(CHEMBL5192792)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at P2X7 receptor in human RPMI-8226 cells assessed as inhibition of ATP-induced Ca2+ influx by fura-2 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Takasaki University of Health and Welfare

Curated by ChEMBL
LigandPNGBDBM50601938(CHEMBL5183752)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at P2X7 receptor in human RPMI-8226 cells assessed as inhibition of ATP-induced Ca2+ influx by fura-2 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed