Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50018519
TargetProprotein convertase subtilisin/kexin type 9(Human)
Aligarh Muslim University

Curated by ChEMBL
LigandPNGBDBM50609094(CHEMBL5273270)
Affinity DataKd:  15nMAssay Description:Binding affinity to human PCSK9More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Mouse)
Aligarh Muslim University

Curated by ChEMBL
LigandPNGBDBM50609097(CHEMBL5271747)
Affinity DataKd:  1nMAssay Description:Binding affinity to mouse PCSK9More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Mouse)
Aligarh Muslim University

Curated by ChEMBL
LigandPNGBDBM50609096(CHEMBL5278292)
Affinity DataKd:  21nMAssay Description:Binding affinity to mouse PCSK9More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Aligarh Muslim University

Curated by ChEMBL
LigandPNGBDBM217366(TVFTSWEEYLDWV | Pep2-8)
Affinity DataEC50:  6.00E+3nMAssay Description:Inhibition of PCSK9 in human HepG2 cells assessed as increase in LDL uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Aligarh Muslim University

Curated by ChEMBL
LigandPNGBDBM217366(TVFTSWEEYLDWV | Pep2-8)
Affinity DataEC50:  5.00E+3nMAssay Description:Inhibition of PCSK9 in human HepG2 cells assessed as restoration of LDLRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Aligarh Muslim University

Curated by ChEMBL
LigandPNGBDBM50609101(CHEMBL5276683)
Affinity DataKd:  2.48E+4nMAssay Description:Binding affinity to PCSK9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Aligarh Muslim University

Curated by ChEMBL
LigandPNGBDBM50609100(CHEMBL5280303)
Affinity DataKd:  1.97E+3nMAssay Description:Binding affinity to PCSK9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Aligarh Muslim University

Curated by ChEMBL
LigandPNGBDBM50609095(CHEMBL5280306)
Affinity DataEC50:  250nMAssay Description:Inhibition of PCSK9 mediated LDLR degradation in human HepG2 cells assessed as restoration of LDLRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Aligarh Muslim University

Curated by ChEMBL
LigandPNGBDBM50609095(CHEMBL5280306)
Affinity DataKd:  5.5nMAssay Description:Binding affinity to human PCSK9More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Aligarh Muslim University

Curated by ChEMBL
LigandPNGBDBM50609093(CHEMBL5279432)
Affinity DataKd:  1.00E+3nMAssay Description:Binding affinity to human PCSK9More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Aligarh Muslim University

Curated by ChEMBL
LigandPNGBDBM217366(TVFTSWEEYLDWV | Pep2-8)
Affinity DataKd:  700nMAssay Description:Binding affinity to human PCSK9More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Aligarh Muslim University

Curated by ChEMBL
LigandPNGBDBM50609096(CHEMBL5278292)
Affinity DataKd:  6.10nMAssay Description:Binding affinity to human PCSK9More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Aligarh Muslim University

Curated by ChEMBL
LigandPNGBDBM50609097(CHEMBL5271747)
Affinity DataKd:  0.300nMAssay Description:Binding affinity to human PCSK9More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Aligarh Muslim University

Curated by ChEMBL
LigandPNGBDBM50609098(CHEMBL5278470)
Affinity DataKd:  390nMAssay Description:Binding affinity to human PCSK9More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Aligarh Muslim University

Curated by ChEMBL
LigandPNGBDBM50460550(CHEMBL4227325)
Affinity DataKd:  700nMAssay Description:Binding affinity to human PCSK9More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Aligarh Muslim University

Curated by ChEMBL
LigandPNGBDBM50609095(CHEMBL5280306)
Affinity DataIC50: 20nMAssay Description:Inhibition of human PCSK9More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Aligarh Muslim University

Curated by ChEMBL
LigandPNGBDBM50609098(CHEMBL5278470)
Affinity DataIC50: 40nMAssay Description:Inhibition of human PCSK9 preincubated for 30 mins followed by ab20 addition and measured after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Aligarh Muslim University

Curated by ChEMBL
LigandPNGBDBM50609099(CHEMBL5280651)
Affinity DataIC50: 140nMAssay Description:Inhibition of human PCSK9 preincubated for 30 mins followed by ab20 addition and measured after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Aligarh Muslim University

Curated by ChEMBL
LigandPNGBDBM50609102(CHEMBL5268026)
Affinity DataIC50: 230nMAssay Description:Inhibition of PCSK9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Aligarh Muslim University

Curated by ChEMBL
LigandPNGBDBM50609094(CHEMBL5273270)
Affinity DataIC50: 600nMAssay Description:Inhibition of human PCSK9More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Aligarh Muslim University

Curated by ChEMBL
LigandPNGBDBM50609099(CHEMBL5280651)
Affinity DataIC50: 700nMAssay Description:Inhibition of human PCSK9More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Aligarh Muslim University

Curated by ChEMBL
LigandPNGBDBM50609098(CHEMBL5278470)
Affinity DataIC50: 720nMAssay Description:Inhibition of human PCSK9 preincubated for 30 mins followed by EGF(A) addition and measured after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Aligarh Muslim University

Curated by ChEMBL
LigandPNGBDBM50460550(CHEMBL4227325)
Affinity DataIC50: 840nMAssay Description:Inhibition of human PCSK9 preincubated for 30 mins followed by ab20 addition and measured after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Aligarh Muslim University

Curated by ChEMBL
LigandPNGBDBM50609098(CHEMBL5278470)
Affinity DataIC50: 1.83E+3nMAssay Description:Inhibition of human PCSK9 preincubated for 30 mins followed by LDLR addition and measured after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Aligarh Muslim University

Curated by ChEMBL
LigandPNGBDBM50609093(CHEMBL5279432)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human PCSK9More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Aligarh Muslim University

Curated by ChEMBL
LigandPNGBDBM50609100(CHEMBL5280303)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of PCSK9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Aligarh Muslim University

Curated by ChEMBL
LigandPNGBDBM50460550(CHEMBL4227325)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of human PCSK9 preincubated for 30 mins followed by EGF(A) addition and measured after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Aligarh Muslim University

Curated by ChEMBL
LigandPNGBDBM50460550(CHEMBL4227325)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human PCSK9 preincubated for 30 mins followed by LDLR addition and measured after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Aligarh Muslim University

Curated by ChEMBL
LigandPNGBDBM50609095(CHEMBL5280306)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human PCSK9 preincubated for 30 mins followed by EGF(A) addition and measured after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Aligarh Muslim University

Curated by ChEMBL
LigandPNGBDBM50609106(CHEMBL5275906)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human PCSK9 preincubated for 30 mins followed by EGF(A) addition and measured after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetProprotein convertase subtilisin/kexin type 9(Human)
Aligarh Muslim University

Curated by ChEMBL
LigandPNGBDBM50609107(CHEMBL5290775)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human PCSK9 preincubated for 30 mins followed by EGF(A) addition and measured after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
Aligarh Muslim University

Curated by ChEMBL
LigandPNGBDBM50609105(CHEMBL5278854)
Affinity DataIC50: 8.89E+4nMAssay Description:Inhibition of HMG CoA reductase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
Aligarh Muslim University

Curated by ChEMBL
LigandPNGBDBM50609103(CHEMBL5287357)
Affinity DataIC50: 1.47E+5nMAssay Description:Inhibition of HMG CoA reductase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
Aligarh Muslim University

Curated by ChEMBL
LigandPNGBDBM50609104(CHEMBL5277547)
Affinity DataIC50: 1.75E+5nMAssay Description:Inhibition of HMG CoA reductase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed