Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50018571
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50435990(VN/124 | VN/124-1 | TOK-001 | GALETERONE | US96112...)
Affinity DataIC50: 12nMAssay Description:Inhibition of CYP17AI in human 22Rv1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50529647(CHEMBL4584527 | US10806720, Compound 17 | US112305...)
Affinity DataKi:  78nMAssay Description:Binding affinity to GST tagged AR LBD (unknown orign) by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetAndrogen receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50609682(CHEMBL5184863)
Affinity DataIC50: 156nMAssay Description:Inhibition of AR LBD in human LNCaP cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetAndrogen receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50529667(CHEMBL4444904 | US10806720, Compound 11 | US112305...)
Affinity DataKi:  267nMAssay Description:Binding affinity to GST tagged AR LBD (unknown orign) by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetAndrogen receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50609683(CHEMBL5279873)
Affinity DataIC50: 293nMAssay Description:Inhibition of AR LBD in human LNCaP cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetAndrogen receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50609682(CHEMBL5184863)
Affinity DataEC50:  1.00E+3nMAssay Description:Induction of degradation of AR LBD in human LNCaP cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetAndrogen receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50609683(CHEMBL5279873)
Affinity DataEC50:  2.00E+3nMAssay Description:Induction of degradation of AR LBD in human LNCaP cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50435990(VN/124 | VN/124-1 | TOK-001 | GALETERONE | US96112...)
Affinity DataIC50: 3.55E+3nMAssay Description:Inhibition of CYP17AI in human LNCaP cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50609684(CHEMBL1390665)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of Androgen receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetAndrogen receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50435990(VN/124 | VN/124-1 | TOK-001 | GALETERONE | US96112...)
Affinity DataEC50:  1.04E+4nMAssay Description:Induction of degradation of full length Androgen receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed