Compile Data Set for Download or QSAR
Report error Found 49 Enz. Inhib. hit(s) with all data for entry = 50019958
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625100(CHEMBL5408197)
Affinity DataKi:  250nMAssay Description:Inhibition of C-terminal His-tagged truncated form of human tyrosinase (1 to 456 residues) expressed in HEK293T cells using L-DOPA as substrate asses...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50559076(CHEMBL4743159)
Affinity DataKi:  250nMAssay Description:Inhibition of truncated His-tagged human tyrosinase catalytic domain expressed in HEK293 cells using L-DOPA as substrate assessed as inhibition const...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625088(CHEMBL5399906)
Affinity DataKi:  550nMAssay Description:Inhibition of C-terminal His-tagged truncated form of human tyrosinase (1 to 456 residues) expressed in HEK293T cells using L-DOPA as substrate asses...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50559076(CHEMBL4743159)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of truncated His-tagged human tyrosinase catalytic domain expressed in HEK293 cells using L-DOPA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625088(CHEMBL5399906)
Affinity DataIC50: 1.57E+3nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625100(CHEMBL5408197)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625104(CHEMBL5416835)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625099(CHEMBL5394983)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50609374(CHEMBL5274383)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625106(CHEMBL5405017)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625105(CHEMBL5428256)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625083(CHEMBL1807311)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625084(CHEMBL1807492)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625090(CHEMBL1814444)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625101(CHEMBL5404839)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50248158(N-butylresorcinol | CHEMBL450195 | US8993596, 4-Bu...)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625094(CHEMBL5412546)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625103(CHEMBL5403418)
Affinity DataIC50: 1.27E+4nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625115(CHEMBL5396899)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50205807(CHEMBL3978212)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625081(CHEMBL5396212)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625091(CHEMBL5425960)
Affinity DataIC50: 1.84E+4nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625082(CHEMBL5418068)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50248158(N-butylresorcinol | CHEMBL450195 | US8993596, 4-Bu...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of truncated His-tagged human tyrosinase expressed in HEK293 cells using L-DOPA as substrate by MBTH dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50609373(CHEMBL1814434)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625096(CHEMBL5394207)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625107(CHEMBL5421537)
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625108(CHEMBL373249)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625089(CHEMBL5427200)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625095(CHEMBL5418183)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625093(CHEMBL5405551)
Affinity DataIC50: 8.80E+4nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625086(CHEMBL5426205)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625087(CHEMBL5435799)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625116(CHEMBL5400587)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625113(CHEMBL5423130)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625085(CHEMBL5411705)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625114(CHEMBL5397672)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625092(CHEMBL1172321)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625098(CHEMBL5399513)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50031467(Kojic Acid | CHEMBL287556 | 5-HYDROXY-2-(HYDROXYME...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625097(CHEMBL5432681)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625102(CHEMBL5404928)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625111(CHEMBL5400410)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625112(CHEMBL5426749)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625109(2',4'-Dihydroxy Flavone | CHEMBL1374610)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625110(CHEMBL5420730)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50031467(Kojic Acid | CHEMBL287556 | 5-HYDROXY-2-(HYDROXYME...)
Affinity DataKi:  3.50E+5nMAssay Description:Mixed type inhibition of human recombinant tyrosinase assessed as inhibition constant using L-DOPA as substrate by double reciprocal plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50031467(Kojic Acid | CHEMBL287556 | 5-HYDROXY-2-(HYDROXYME...)
Affinity DataKi:  1.10E+6nMAssay Description:Inhibition of C-terminal His-tagged truncated form of human tyrosinase (1 to 456 residues) expressed in HEK293T cells using L-DOPA as substrate asses...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM26189(CHEMBL24147 | benzene-1,3-diol | 1,3-dihydroxybenz...)
Affinity DataIC50: 3.00E+6nMAssay Description:Inhibition of human tyrosinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed