Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50019511
TargetAutotaxin(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50074700(Phosphoric acid mono-[2-((Z)-octadec-9-enoylamino)...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human NPP2 expressed in COS-7 cells using pNP-TMP as substrate preincubated for 10 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
LigandPNGBDBM50510619(CHEMBL4585698)
Affinity DataIC50: 254nMAssay Description:Inhibition of human NPP3 expressed in COS-7 cells using pNP-TMP as substrate preincubated for 10 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCarbonic anhydrase 9(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50620059(CHEMBL5432925)
Affinity DataIC50: 330nMAssay Description:Inhibition of Carbonic anhydrase 9 (unknown origin) using p-nitrophenyl acetate as substrate preincubated for 10 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
LigandPNGBDBM50510619(CHEMBL4585698)
Affinity DataIC50: 564nMAssay Description:Inhibition of human NPP1 expressed in COS-7 cells using pNP-TMP as substrate preincubated for 10 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCarbonic anhydrase 12(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50620059(CHEMBL5432925)
Affinity DataIC50: 680nMAssay Description:Inhibition of Carbonic anhydrase 12 (unknown origin) using p-nitrophenyl acetate as substrate preincubated for 10 mins followed by substrate addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
LigandPNGBDBM50620059(CHEMBL5432925)
Affinity DataIC50: 740nMAssay Description:Inhibition of human NPP3 expressed in COS-7 cells using pNP-TMP as substrate preincubated for 10 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50620058(CHEMBL5404116)
Affinity DataIC50: 880nMAssay Description:Inhibition of Carbonic anhydrase 2 (unknown origin) using p-nitrophenyl acetate as substrate preincubated for 10 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
LigandPNGBDBM50179360(CHEMBL3040216)
Affinity DataIC50: 900nMAssay Description:Inhibition of human NPP3 expressed in COS-7 cells using pNP-TMP as substrate preincubated for 10 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCarbonic anhydrase 9(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50620058(CHEMBL5404116)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of Carbonic anhydrase 9 (unknown origin) using p-nitrophenyl acetate as substrate preincubated for 10 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAutotaxin(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50620059(CHEMBL5432925)
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of human NPP2 expressed in COS-7 cells using pNP-TMP as substrate preincubated for 10 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCarbonic anhydrase 9(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of Carbonic anhydrase 9 (unknown origin) using p-nitrophenyl acetate as substrate preincubated for 10 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
LigandPNGBDBM50620059(CHEMBL5432925)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of human NPP1 expressed in COS-7 cells using pNP-TMP as substrate preincubated for 10 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of Carbonic anhydrase 2 (unknown origin) using p-nitrophenyl acetate as substrate preincubated for 10 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAutotaxin(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50620058(CHEMBL5404116)
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of human NPP2 expressed in COS-7 cells using pNP-TMP as substrate preincubated for 10 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
LigandPNGBDBM50620058(CHEMBL5404116)
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of human NPP1 expressed in COS-7 cells using pNP-TMP as substrate preincubated for 10 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCarbonic anhydrase 12(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataIC50: 1.55E+3nMAssay Description:Inhibition of Carbonic anhydrase 12 (unknown origin) using p-nitrophenyl acetate as substrate preincubated for 10 mins followed by substrate addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50620058(CHEMBL5404116)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human NPP3 expressed in COS-7 cells using pNP-TMP as substrate preincubated for 10 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
LigandPNGBDBM50179360(CHEMBL3040216)
Affinity DataIC50: 7.77E+3nMAssay Description:Inhibition of human NPP1 expressed in COS-7 cells using pNP-TMP as substrate preincubated for 10 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed