Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50018594
TargetPoly [ADP-ribose] polymerase 1(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50609914(CHEMBL5275672)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50536935(CHEMBL4533690)
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant PARP1 by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50609912(CHEMBL5267691)
Affinity DataIC50: 14nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50609913(CHEMBL5274451)
Affinity DataIC50: 20nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50446130(AG-014699 | AG-14447 | Rucaparib | RUCAPARIB CAMSY...)
Affinity DataIC50: 24nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50609915(CHEMBL5278111)
Affinity DataIC50: 25nMAssay Description:Inhibition of PARP1 (unknown origin) incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50589151(CHEMBL5202615)
Affinity DataIC50: 36nMAssay Description:Inhibition of PARP1 (unknown origin) incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50609914(CHEMBL5275672)
Affinity DataIC50: 65nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50536935(CHEMBL4533690)
Affinity DataIC50: 68nMAssay Description:Inhibition of human recombinant PARP2 by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 80nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50536938(CHEMBL4521684)
Affinity DataIC50: 97nMAssay Description:Inhibition of PARP1 (unknown origin) incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50: 139nMAssay Description:Inhibition of PARP1 (unknown origin) incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50129952(cid_5281600 | CHEMBL63354 | 8-[5-(5,7-Dihydroxy-4-...)
Affinity DataIC50: 198nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP16(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50609916(CHEMBL5284069)
Affinity DataIC50: 362nMAssay Description:Inhibition of PARP16 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50597849(CHEMBL5205994)
Affinity DataIC50: 400nMAssay Description:Inhibition of BRD4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50597849(CHEMBL5205994)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50129952(cid_5281600 | CHEMBL63354 | 8-[5-(5,7-Dihydroxy-4-...)
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of PARP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP3(Human)
Shandong First Medical University and Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50609916(CHEMBL5284069)
Affinity DataIC50: 7.41E+4nMAssay Description:Inhibition of PARP3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed