Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50018167
TargetHeat shock protein HSP 90-alpha(Human)
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50489435(CHEMBL2326381)
Affinity DataKd:  1.91E+5nMAssay Description:Binding affinity to recombinant HSP90alpha (unknown origin) assessed as dissociation constant incubated for 30 mins by intrinsic fluorescence based s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetHeat shock protein HSP 90-beta(Human)
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50489435(CHEMBL2326381)
Affinity DataKd:  7.26E+5nMAssay Description:Binding affinity to recombinant HSP90beta (unknown origin) assessed as dissociation constant incubated for 30 mins by intrinsic fluorescence based sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50405644(CHEMBL5281169)
Affinity DataKd:  2.74E+4nMAssay Description:Binding affinity to NT-647 labelled recombinant HSP90 (unknown origin) C-terminal domain assessed as dissociation constant by microscale thermophores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50405645(CHEMBL5274366)
Affinity DataKd:  3.42E+3nMAssay Description:Binding affinity to human recombinant HSP90alpha C-terminal domain (563 to 732 residues) expressed in Escherichia coli BL21(DE3) cells assessed as di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50405646(CHEMBL5267930)
Affinity DataKd:  3.80E+3nMAssay Description:Binding affinity to human HSP90alpha assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetHeat shock protein HSP 90-beta(Human)
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50405646(CHEMBL5267930)
Affinity DataKd:  9.70E+3nMAssay Description:Binding affinity to human HSP90beta assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50405648(CHEMBL5282664)
Affinity DataKd:  21nMAssay Description:Binding affinity to recombinant human HSP90alpha assessed as dissociation constant measured for 300 secs by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50405649(CHEMBL5282185)
Affinity DataKd:  21nMAssay Description:Binding affinity to recombinant human HSP90alpha assessed as dissociation constant measured for 300 secs by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50405647(CHEMBL2008313)
Affinity DataIC50: 1.19E+5nMAssay Description:Inhibition of recombinant GST-tagged HSP90alpha NTD (9 to 236 residues) (unknown origin) ATPase activity expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed