Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50019340
TargetTyrosinase(Mouse)
University of Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50618270(CHEMBL5436239)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of tyrosinase in mouse B16-F10 cells assessed as inhibition of melanin production measured after 72 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTyrosinase(Mouse)
University of Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50205814(CHEMBL3898657)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of tyrosinase in mouse B16-F10 cells assessed as inhibition of melanin production measured after 72 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTyrosinase(Mouse)
University of Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50618269(CHEMBL5434151)
Affinity DataIC50: 6.13E+4nMAssay Description:Inhibition of tyrosinase in mouse B16-F10 cells assessed as inhibition of melanin production measured after 72 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University of Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50618271(CHEMBL5434506)
Affinity DataIC50: 7.36E+4nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates assessed as inhibition of melanin production using L-DOPA as substrate measured after 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University of Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50618270(CHEMBL5436239)
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates assessed as inhibition of melanin production using L-DOPA as substrate measured after 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTyrosinase(Mouse)
University of Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50031467(Kojic Acid | CHEMBL287556 | 5-HYDROXY-2-(HYDROXYME...)
Affinity DataIC50: 1.08E+5nMAssay Description:Inhibition of tyrosinase in mouse B16-F10 cells assessed as inhibition of melanin production measured after 72 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University of Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50205814(CHEMBL3898657)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of tyrosinase in human MNT-1 cells assessed as inhibition of melanin production measured after 96 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University of Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50618272(CHEMBL5432409)
Affinity DataIC50: 2.77E+5nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates assessed as inhibition of melanin production using L-DOPA as substrate measured after 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University of Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50618272(CHEMBL5432409)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of tyrosinase in human MNT-1 cells assessed as inhibition of melanin production measured after 96 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University of Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50618270(CHEMBL5436239)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of tyrosinase in human MNT-1 cells assessed as inhibition of melanin production measured after 96 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University of Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50618271(CHEMBL5434506)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of tyrosinase in human MNT-1 cells assessed as inhibition of melanin production measured after 96 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University of Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50205814(CHEMBL3898657)
Affinity DataIC50: 1.30E+6nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates assessed as inhibition of melanin production using L-DOPA as substrate measured after 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTyrosinase(Streptomyces antibioticus)
University of Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50618269(CHEMBL5434151)
Affinity DataKi:  4.10E+3nMAssay Description:Competitive inhibition of Streptomyces antibioticus tyrosinase using L-DOPA as substrate by Michelis-Menten based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University of Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50618270(CHEMBL5436239)
Affinity DataKi:  6.00E+3nMAssay Description:Competitive inhibition of human recombinant tyrosinase expressed in Sf9 cells using L-DOPA as substrate by Michelis-Menten based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University of Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50618269(CHEMBL5434151)
Affinity DataKi:  7.50E+3nMAssay Description:Competitive inhibition of human recombinant tyrosinase expressed in Sf9 cells using L-DOPA as substrate by Michelis-Menten based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTyrosinase(Streptomyces antibioticus)
University of Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50205814(CHEMBL3898657)
Affinity DataKi:  7.70E+3nMAssay Description:Competitive inhibition of Streptomyces antibioticus tyrosinase using L-DOPA as substrate by Michelis-Menten based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University of Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50618271(CHEMBL5434506)
Affinity DataKi:  8.00E+3nMAssay Description:Competitive inhibition of human recombinant tyrosinase expressed in Sf9 cells using L-DOPA as substrate by Michelis-Menten based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTyrosinase(Streptomyces antibioticus)
University of Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50618272(CHEMBL5432409)
Affinity DataKi:  1.60E+4nMAssay Description:Competitive inhibition of Streptomyces antibioticus tyrosinase using L-DOPA as substrate by Michelis-Menten based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTyrosinase(Streptomyces antibioticus)
University of Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50618271(CHEMBL5434506)
Affinity DataKi:  3.90E+4nMAssay Description:Competitive inhibition of Streptomyces antibioticus tyrosinase using L-DOPA as substrate by Michelis-Menten based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTyrosinase(Streptomyces antibioticus)
University of Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50618270(CHEMBL5436239)
Affinity DataKi:  4.20E+4nMAssay Description:Competitive inhibition of Streptomyces antibioticus tyrosinase using L-DOPA as substrate by Michelis-Menten based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University of Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50618272(CHEMBL5432409)
Affinity DataKi:  7.60E+4nMAssay Description:Competitive inhibition of human recombinant tyrosinase expressed in Sf9 cells using L-DOPA as substrate by Michelis-Menten based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTyrosinase(Streptomyces antibioticus)
University of Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50031467(Kojic Acid | CHEMBL287556 | 5-HYDROXY-2-(HYDROXYME...)
Affinity DataKi:  1.09E+5nMAssay Description:Competitive inhibition of Streptomyces antibioticus tyrosinase using L-DOPA as substrate by Michelis-Menten based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University of Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50205814(CHEMBL3898657)
Affinity DataKi:  1.28E+5nMAssay Description:Competitive inhibition of human recombinant tyrosinase expressed in Sf9 cells using L-DOPA as substrate by Michelis-Menten based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University of Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50031467(Kojic Acid | CHEMBL287556 | 5-HYDROXY-2-(HYDROXYME...)
Affinity DataKi:  3.50E+5nMAssay Description:Competitive inhibition of human recombinant tyrosinase expressed in Sf9 cells using L-DOPA as substrate by Michelis-Menten based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University of Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50031467(Kojic Acid | CHEMBL287556 | 5-HYDROXY-2-(HYDROXYME...)
Affinity DataKi:  7.30E+5nMAssay Description:Uncompetitive inhibition of human recombinant tyrosinase expressed in Sf9 cells using L-DOPA as substrate by Michelis-Menten based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed