Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 50018184
TargetGlutaminase kidney isoform, mitochondrial(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM109086(US8604016, 670 | US9938267, Cmpd ID 670 | US107935...)
Affinity DataKd:  1.5nMAssay Description:Binding affinity to wild type human KGA assessed as covalent bond formation by measuring dissociation constant by biomolecular interaction assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetGlutaminase kidney isoform, mitochondrial(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50405872(CHEMBL5281625)
Affinity DataIC50: 28nMAssay Description:Inhibition of human KGA using glutamine as substrate preincubated for 0.5 hrs followed by substrate addition and measured after 4 hrs by EZMTT reagen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50405871(CHEMBL5267355)
Affinity DataIC50: 50nMAssay Description:Inhibition of human KGA using glutamine as substrate preincubated for 0.5 hrs followed by substrate addition and measured after 4 hrs by EZMTT reagen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed