Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50019532
TargetTelomerase reverse transcriptase(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50126186(2-(3-Naphthalen-2-yl-but-2-enoylamino)-benzoic aci...)
Affinity DataIC50: 93nMAssay Description:Inhibition of recombinant His-tagged human telomerase expressed in insect cells preincubated for 15 mins followed by dNTPs and oligonucleotide primer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTelomerase reverse transcriptase(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50134030(N,N'-(9-{[4-(dimethylamino)phenyl]amino}acridine-3...)
Affinity DataIC50: 115nMAssay Description:Inhibition of human telomerase incubated for 20 mins by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTelomerase reverse transcriptase(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50431630(KRX-0401 | PERIFOSINE)
Affinity DataIC50: 184nMAssay Description:Inhibition of telomerase activity in human HCC2429 cells by droplet-digital TRAP PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTelomerase reverse transcriptase(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50431630(KRX-0401 | PERIFOSINE)
Affinity DataIC50: 184nMAssay Description:Inhibition of telomerase activity in human HCC38 cells by droplet-digital TRAP PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTelomerase reverse transcriptase(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50431630(KRX-0401 | PERIFOSINE)
Affinity DataIC50: 184nMAssay Description:Inhibition of telomerase activity in human NCI-H1819 cells by droplet-digital TRAP PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTelomerase reverse transcriptase(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50431630(KRX-0401 | PERIFOSINE)
Affinity DataIC50: 184nMAssay Description:Inhibition of telomerase activity in human NCI-H2882 cells by droplet-digital TRAP PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTelomerase reverse transcriptase(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50431630(KRX-0401 | PERIFOSINE)
Affinity DataIC50: 184nMAssay Description:Inhibition of telomerase activity in human NCI-H1993 cells by droplet-digital TRAP PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTelomerase reverse transcriptase(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50431630(KRX-0401 | PERIFOSINE)
Affinity DataIC50: 184nMAssay Description:Inhibition of telomerase activity in human NCI-H2009 cells by droplet-digital TRAP PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTelomerase reverse transcriptase(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50431630(KRX-0401 | PERIFOSINE)
Affinity DataIC50: 184nMAssay Description:Inhibition of telomerase activity in human HCC827 cells by droplet-digital TRAP PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTelomerase reverse transcriptase(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50431630(KRX-0401 | PERIFOSINE)
Affinity DataIC50: 184nMAssay Description:Inhibition of telomerase activity in human HCC515 cells by droplet-digital TRAP PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTelomerase reverse transcriptase(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50431630(KRX-0401 | PERIFOSINE)
Affinity DataIC50: 184nMAssay Description:Inhibition of telomerase activity in human HCC4017 cells by droplet-digital TRAP PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTelomerase reverse transcriptase(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50431630(KRX-0401 | PERIFOSINE)
Affinity DataIC50: 184nMAssay Description:Inhibition of telomerase activity in human HCC15 cells by droplet-digital TRAP PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTelomerase reverse transcriptase(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50446424(U-73122 | CHEMBL1256678)
Affinity DataIC50: 200nMAssay Description:Inhibition of telomerase (unknown origin) by PCR-based TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTelomerase reverse transcriptase(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50108802(3,11-difluoro-6,8,13-trimethyl-8H-quino[4,3,2-kl]a...)
Affinity DataIC50: 330nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTelomerase reverse transcriptase(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50620246(CHEMBL5421589)
Affinity DataIC50: 440nMAssay Description:Inhibition of telomerase activity in human MGC-803 cells incubated for 24 hrs by TRAP-PCR-ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTelomerase reverse transcriptase(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50620241(CHEMBL5396635)
Affinity DataIC50: 500nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTelomerase reverse transcriptase(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50620242(CHEBI:78039 | CHEMBL2170855)
Affinity DataIC50: 650nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTelomerase reverse transcriptase(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50620239(CHEMBL5423982)
Affinity DataIC50: 980nMAssay Description:Inhibition of recombinant His-tagged human telomerase expressed in insect cells preincubated for 15 mins followed by dNTPs and oligonucleotide primer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTelomerase reverse transcriptase(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50568582(CHEMBL4857212)
Affinity DataIC50: 980nMAssay Description:Inhibition of telomerase activity in human SGC-7901 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTelomerase reverse transcriptase(Rat)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50446425(CHEMBL3109741)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of rat telomerase assessed as incorporation of radioactive substrate into product DNA using [32P]dGTP and dNTPs as substrate incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTelomerase reverse transcriptase(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50396097(CHEMBL2170856)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTelomerase reverse transcriptase(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50620244(CHEMBL5431445)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of telomerase (unknown origin) by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTelomerase reverse transcriptase(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50620243(CHEMBL5418047)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTelomerase reverse transcriptase(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50620240(CHEMBL5408379)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTelomerase reverse transcriptase(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50620245(CHEMBL5439399)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of telomerase activity in human HeLa cells incubated for 24 hrs by TRAP-PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed