Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50019534
TargetAmine oxidase [flavin-containing] A(Human)
North Sichuan Medical College

Curated by ChEMBL
LigandPNGBDBM15581(US8633208, Clorgyline | [3-(2,4-dichlorophenoxy)pr...)
Affinity DataIC50: 3nMAssay Description:Inhibition of MAO-A (unknown origin) using kynuramine as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAmine oxidase [flavin-containing] B(Human)
North Sichuan Medical College

Curated by ChEMBL
LigandPNGBDBM50620258(CHEMBL5414700)
Affinity DataIC50: 14nMAssay Description:Inhibition of MAO-B (unknown origin) using kynuramine as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North Sichuan Medical College

Curated by ChEMBL
LigandPNGBDBM50620263(CHEMBL5415223)
Affinity DataIC50: 21nMAssay Description:Inhibition of MAO-B (unknown origin) using kynuramine as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North Sichuan Medical College

Curated by ChEMBL
LigandPNGBDBM50620265(CHEMBL5414652)
Affinity DataIC50: 33nMAssay Description:Inhibition of MAO-B (unknown origin) using kynuramine as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North Sichuan Medical College

Curated by ChEMBL
LigandPNGBDBM50620266(CHEMBL5398247)
Affinity DataIC50: 35nMAssay Description:Inhibition of MAO-B (unknown origin) using kynuramine as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North Sichuan Medical College

Curated by ChEMBL
LigandPNGBDBM50620264(CHEMBL5441072)
Affinity DataIC50: 49nMAssay Description:Inhibition of MAO-B (unknown origin) using kynuramine as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North Sichuan Medical College

Curated by ChEMBL
LigandPNGBDBM19187(CHEMBL396778 | (2S)-2-[({4-[(3-fluorophenyl)methox...)
Affinity DataIC50: 52nMAssay Description:Inhibition of MAO-B (unknown origin) using kynuramine as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North Sichuan Medical College

Curated by ChEMBL
LigandPNGBDBM50620259(CHEMBL5430381)
Affinity DataIC50: 58nMAssay Description:Inhibition of MAO-B (unknown origin) using kynuramine as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North Sichuan Medical College

Curated by ChEMBL
LigandPNGBDBM50620267(CHEMBL5427279)
Affinity DataIC50: 67nMAssay Description:Inhibition of MAO-B (unknown origin) using kynuramine as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North Sichuan Medical College

Curated by ChEMBL
LigandPNGBDBM50620262(CHEMBL5394801)
Affinity DataIC50: 85nMAssay Description:Inhibition of MAO-B (unknown origin) using kynuramine as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North Sichuan Medical College

Curated by ChEMBL
LigandPNGBDBM10989((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...)
Affinity DataIC50: 94nMAssay Description:Inhibition of MAO-B (unknown origin) using kynuramine as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North Sichuan Medical College

Curated by ChEMBL
LigandPNGBDBM50620254(CHEMBL5400685)
Affinity DataIC50: 95nMAssay Description:Inhibition of MAO-B (unknown origin) using kynuramine as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North Sichuan Medical College

Curated by ChEMBL
LigandPNGBDBM50620255(CHEMBL5426461)
Affinity DataIC50: 249nMAssay Description:Inhibition of MAO-B (unknown origin) using kynuramine as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North Sichuan Medical College

Curated by ChEMBL
LigandPNGBDBM50620256(CHEMBL5418090)
Affinity DataIC50: 297nMAssay Description:Inhibition of MAO-B (unknown origin) using kynuramine as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North Sichuan Medical College

Curated by ChEMBL
LigandPNGBDBM50620252(CHEMBL5394462)
Affinity DataIC50: 334nMAssay Description:Inhibition of MAO-B (unknown origin) using kynuramine as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North Sichuan Medical College

Curated by ChEMBL
LigandPNGBDBM50620257(CHEMBL5403831)
Affinity DataIC50: 343nMAssay Description:Inhibition of MAO-B (unknown origin) using kynuramine as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North Sichuan Medical College

Curated by ChEMBL
LigandPNGBDBM50620260(CHEMBL5416185)
Affinity DataIC50: 366nMAssay Description:Inhibition of MAO-B (unknown origin) using kynuramine as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North Sichuan Medical College

Curated by ChEMBL
LigandPNGBDBM50620253(CHEMBL5438301)
Affinity DataIC50: 423nMAssay Description:Inhibition of MAO-B (unknown origin) using kynuramine as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North Sichuan Medical College

Curated by ChEMBL
LigandPNGBDBM50620261(CHEMBL5399743)
Affinity DataIC50: 435nMAssay Description:Inhibition of MAO-B (unknown origin) using kynuramine as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North Sichuan Medical College

Curated by ChEMBL
LigandPNGBDBM50620251(CHEMBL5428123)
Affinity DataIC50: 481nMAssay Description:Inhibition of MAO-B (unknown origin) using kynuramine as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North Sichuan Medical College

Curated by ChEMBL
LigandPNGBDBM29136(Iprazid | Euphozid | CHEMBL92401 | Iproniazid)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of MAO-B (unknown origin) using kynuramine as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North Sichuan Medical College

Curated by ChEMBL
LigandPNGBDBM10989((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...)
Affinity DataIC50: 1.31E+3nMAssay Description:Inhibition of MAO-A (unknown origin) using kynuramine as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North Sichuan Medical College

Curated by ChEMBL
LigandPNGBDBM29136(Iprazid | Euphozid | CHEMBL92401 | Iproniazid)
Affinity DataIC50: 1.92E+3nMAssay Description:Inhibition of MAO-A (unknown origin) using kynuramine as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North Sichuan Medical College

Curated by ChEMBL
LigandPNGBDBM15581(US8633208, Clorgyline | [3-(2,4-dichlorophenoxy)pr...)
Affinity DataIC50: 3.76E+3nMAssay Description:Inhibition of MAO-B (unknown origin) using kynuramine as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North Sichuan Medical College

Curated by ChEMBL
LigandPNGBDBM50620258(CHEMBL5414700)
Affinity DataKi:  18nMAssay Description:Competitive inhibition of MAO-B (unknown origin) using kynuramine as substrate assessed as inhibition constant by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed