Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 50018918
TargetTumor necrosis factor(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50552392(CHEMBL4743779)
Affinity DataKd:  13nMAssay Description:Binding affinity to human TNF-alpha assessed as dissociation constant by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetInterleukin-17A(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50581143(CHEMBL5077648)
Affinity DataKd:  660nMAssay Description:Binding affinity to biotinylated Bap-tagged human IL-17A assessed as dissociation constant by SPR binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTumor necrosis factor(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM56191(MLS000063267 | [1-[(2,5-dimethylphenyl)methyl]benz...)
Affinity DataKd:  2.20E+4nMAssay Description:Binding affinity to human TNF-alpha assessed as dissociation constant by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)