Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50019578
TargetNicotinamide phosphoribosyltransferase(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM81395(APO-866 | US20240327418, Example FK866 | US2024030...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of full-length recombinant human NAMPT (2 to 491 residues) expressed in Escherichia coli using NAM as substrate preincubated for 5 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetNicotinamide phosphoribosyltransferase(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50620671(CHEMBL5428441)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of full-length recombinant human NAMPT (2 to 491 residues) expressed in Escherichia coli using NAM as substrate preincubated for 5 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50620673(CHEMBL5416318)
Affinity DataIC50: 5nMAssay Description:Inhibition of full-length recombinant human NAMPT (2 to 491 residues) expressed in Escherichia coli using NAM as substrate preincubated for 5 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50620672(CHEMBL5421145)
Affinity DataIC50: 12nMAssay Description:Inhibition of full-length recombinant human NAMPT (2 to 491 residues) expressed in Escherichia coli using NAM as substrate preincubated for 5 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50620670(CHEMBL5396894)
Affinity DataIC50: 69nMAssay Description:Inhibition of full-length recombinant human NAMPT (2 to 491 residues) expressed in Escherichia coli using NAM as substrate preincubated for 5 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed