Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50018833
TargetTaste receptor type 2 member 14(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50613033(CHEMBL5279691)
Affinity DataEC50:  72nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50613028(CHEMBL5285591)
Affinity DataEC50:  98nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50613041(CHEMBL5275180)
Affinity DataEC50:  100nMAssay Description:Partial agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50613023(CHEMBL5273955)
Affinity DataEC50:  150nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50613032(CHEMBL5274304)
Affinity DataEC50:  160nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50613021(CHEMBL5277615)
Affinity DataEC50:  170nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50613040(CHEMBL5280542)
Affinity DataEC50:  180nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50124575(CHEMBL3623735)
Affinity DataEC50:  190nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50613015(CHEMBL5279381)
Affinity DataEC50:  190nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50613019(CHEMBL3088246)
Affinity DataEC50:  230nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50613038(CHEMBL5277281)
Affinity DataEC50:  300nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50613018(CHEMBL5278834)
Affinity DataEC50:  300nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50613014(CHEMBL5278171)
Affinity DataEC50:  330nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50613030(CHEMBL5274470)
Affinity DataEC50:  360nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50613024(CHEMBL5278477)
Affinity DataEC50:  380nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50613016(CHEMBL5275001)
Affinity DataEC50:  390nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50613022(CHEMBL5289590)
Affinity DataEC50:  420nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)
Affinity DataEC50:  430nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTaste receptor type 2 member 14(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50613036(CHEMBL5280688)
Affinity DataEC50:  540nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50613020(CHEMBL5286379)
Affinity DataEC50:  640nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50613034(CHEMBL5268924)
Affinity DataEC50:  640nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50613025(CHEMBL5279341)
Affinity DataEC50:  670nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50613037(CHEMBL5289980)
Affinity DataEC50:  750nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50613012(CHEMBL5276181)
Affinity DataEC50:  930nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50385711(CHEMBL22815)
Affinity DataEC50:  950nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50613033(CHEMBL5279691)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of [3H]methylspiperone from human D3 receptor stably expressed in HEK293T cells by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50613031(CHEMBL5265924)
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50613026(CHEMBL5268477)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50613039(CHEMBL5280454)
Affinity DataEC50:  1.40E+3nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50613027(CHEMBL5274977)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50613013(CHEMBL5285283)
Affinity DataEC50:  1.80E+3nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50613017(CHEMBL5288875)
Affinity DataEC50:  2.10E+3nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50613033(CHEMBL5279691)
Affinity DataKi:  2.30E+3nMAssay Description:Displacement of [3H]NMS from human M2 receptor stably expressed in HEK293T cells by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50613029(CHEMBL5265867)
Affinity DataEC50:  3.50E+3nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTaste receptor type 2 member 14(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50613035(CHEMBL5279932)
Affinity DataEC50:  6.80E+3nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50613033(CHEMBL5279691)
Affinity DataKi:  7.30E+3nMAssay Description:Displacement of [3H]methylspiperone from human D2S receptor stably expressed in CHO cells by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAlpha-2B adrenergic receptor(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50613023(CHEMBL5273955)
Affinity DataKi:  1.60E+4nMAssay Description:Displacement of [3H]RX821002 from human alpha2B receptor stably expressed in HEK293T cells by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50613033(CHEMBL5279691)
Affinity DataKi:  1.60E+4nMAssay Description:Displacement of [3H]methylspiperone from human D2L receptor stably expressed in CHO cells by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50613023(CHEMBL5273955)
Affinity DataKi:  1.70E+4nMAssay Description:Displacement of [3H]RX821002 from human alpha2C receptor stably expressed in HEK293T cells by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed