Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50020148
TargetReplicase polyprotein 1ab(2019-nCoV)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50626718(CHEMBL5439487)
Affinity DataEC50:  1.70E+3nMAssay Description:Inhibition of SARS-CoV-2 RdRp transfected in HEK293T cells incubated for 24 hrs by CCK-8 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50626719(CHEMBL5427660)
Affinity DataEC50:  1.41E+3nMAssay Description:Inhibition of SARS-CoV-2 RdRp transfected in HEK293T cells incubated for 24 hrs by CCK-8 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50626720(CHEMBL5436683)
Affinity DataEC50:  2.75E+3nMAssay Description:Inhibition of SARS-CoV-2 RdRp transfected in HEK293T cells incubated for 24 hrs by CCK-8 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50626721(CHEMBL5419575)
Affinity DataEC50:  2.53E+3nMAssay Description:Inhibition of SARS-CoV-2 RdRp transfected in HEK293T cells incubated for 24 hrs by CCK-8 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50626722(CHEMBL5398270)
Affinity DataEC50:  3.07E+3nMAssay Description:Inhibition of SARS-CoV-2 RdRp transfected in HEK293T cells incubated for 24 hrs by CCK-8 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM429505(Remdesivir | med.21724, Compound 178 | US202400347...)
Affinity DataEC50:  1.05E+3nMAssay Description:Inhibition of SARS-CoV-2 RdRp transfected in HEK293T cells incubated for 24 hrs by CCK-8 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50626718(CHEMBL5439487)
Affinity DataEC50:  1.58E+3nMAssay Description:Inhibition of SARS-CoV-2 RdRp transfected in human A549 cells incubated for 24 hrs by CCK-8 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50626719(CHEMBL5427660)
Affinity DataEC50:  1.18E+3nMAssay Description:Inhibition of SARS-CoV-2 RdRp transfected in human A549 cells incubated for 24 hrs by CCK-8 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM429505(Remdesivir | med.21724, Compound 178 | US202400347...)
Affinity DataEC50:  730nMAssay Description:Inhibition of SARS-CoV-2 RdRp transfected in human A549 cells incubated for 24 hrs by CCK-8 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50179360(CHEMBL3040216)
Affinity DataIC50: 260nMAssay Description:Inhibition of SARS-CoV-2 RdRp expressed in Escherichia coli BL21 (DE3) cells incubated for 60 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50236025(CHEMBL2016761 | US11149049, No. C2 | US20240140975...)
Affinity DataIC50: 6.21E+3nMAssay Description:Inhibition of SARS-CoV-2 RdRp expressed in Escherichia coli BL21 (DE3) cells incubated for 60 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)