Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50020695
TargetBifunctional epoxide hydrolase 2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM25744(3-(1-acetylpiperidin-4-yl)-1-[4-(trifluoromethoxy)...)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of sEH (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50632819(CHEMBL5412763)
Affinity DataEC50:  9.80nMAssay Description:Agonist activity at Kv7.2/Kv7.3 (unknown origin) expressed in human HEK293 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50192689(CHEMBL3934636)
Affinity DataIC50: 37nMAssay Description:Inhibition of Cav3.1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSodium channel protein type 8 subunit alpha(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM374005(US10246453, Example 272 | (R)-4-((1-benzylpyrrolid...)
Affinity DataIC50: 51nMAssay Description:Inhibition of human Nav1.6 expressed in HEK293 cells by automated patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50192689(CHEMBL3934636)
Affinity DataIC50: 73nMAssay Description:Inhibition of Cav3.2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1I(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50192689(CHEMBL3934636)
Affinity DataIC50: 86nMAssay Description:Inhibition of Cav3.3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50259814(CHEMBL4062225)
Affinity DataKi:  118nMAssay Description:Positive allosteric modulation of GABAA alpha2 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50259814(CHEMBL4062225)
Affinity DataKi:  205nMAssay Description:Positive allosteric modulation of GABAA alpha3 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50632818(CHEMBL5404454)
Affinity DataEC50:  310nMAssay Description:Agonist activity at Kv7.2/Kv7.3 (unknown origin) expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50632817(CHEMBL5174234)
Affinity DataEC50:  990nMAssay Description:Agonist activity at Kv7.2 (unknown origin) expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50143558(CHEMBL41355 | N-(2-amino-4-(4-fluorobenzylamino)-p...)
Affinity DataEC50:  1.84E+3nMAssay Description:Agonist activity at Kv7.2/Kv7.3 (unknown origin) expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50143558(CHEMBL41355 | N-(2-amino-4-(4-fluorobenzylamino)-p...)
Affinity DataEC50:  2.04E+3nMAssay Description:Agonist activity at Kv7.2 (unknown origin) expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSodium channel protein type 2 subunit alpha(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50632816(CHEMBL5399775)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human Nav1.2 expressed in CHO cells by whole-cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target4-aminobutyrate aminotransferase, mitochondrial(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50561618(CHEMBL4746439)
Affinity DataIC50: 9.69E+3nMAssay Description:Inhibition of GABA-AT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target4-aminobutyrate aminotransferase, mitochondrial(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50632823(CHEMBL4740703)
Affinity DataIC50: 1.22E+4nMAssay Description:Inhibition of GABA-AT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target4-aminobutyrate aminotransferase, mitochondrial(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50632821(CHEMBL4750359)
Affinity DataIC50: 1.84E+4nMAssay Description:Inhibition of GABA-AT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target4-aminobutyrate aminotransferase, mitochondrial(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50632822(CHEMBL5408239)
Affinity DataIC50: 1.92E+4nMAssay Description:Inhibition of GABA-AT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target4-aminobutyrate aminotransferase, mitochondrial(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50632820(CHEMBL5404015)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of GABA-AT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed