Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50019349
TargetSerine/threonine-protein phosphatase 5(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50618393(CHEMBL1343129)
Affinity DataKd:  7.80E+3nMAssay Description:Binding affinity to rat PPP5C (428 to 430 residues) phosphatase domain expressed in Escherichia coli BL21-codonplus (DE3)-RIL cells using para-nitrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50367033(COENZYME_A)
Affinity DataEC50:  1nMAssay Description:Activation of PPP5C (unknown origin) TPR domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM22319([1-14C]Arachidonic acid | (5Z,8Z,11Z,14Z)-icosa-5,...)
Affinity DataEC50:  7.76E+4nMAssay Description:Activation of PPP5C (unknown origin) TPR domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50618394(CHEMBL5402473)
Affinity DataEC50:  1.35E+5nMAssay Description:Activation of PPP5C (unknown origin) TPR domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50110690(CHEMBL17377 | Phosphoric acid mono-{3,10-dihydroxy...)
Affinity DataIC50: 1nMAssay Description:Inhibition of PPP5C (unknown origin) phosphatase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50061067(8-[3-amino(imino)methylaminopropyl]-15-isobutyl-5-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of PPP5C (unknown origin) phosphatase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase with EF-hands 1(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50110690(CHEMBL17377 | Phosphoric acid mono-{3,10-dihydroxy...)
Affinity DataIC50: 1nMAssay Description:Inhibition of PP7 (unknown origin) phosphatase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 4 catalytic subunit(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50110690(CHEMBL17377 | Phosphoric acid mono-{3,10-dihydroxy...)
Affinity DataIC50: 3nMAssay Description:Inhibition of PP4 (unknown origin) phosphatase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50090505((1R,7S)-2,6-Dimethyl-4,10-dioxa-tricyclo[5.2.1.0*2...)
Affinity DataIC50: 600nMAssay Description:Inhibition of PPP5C (unknown origin) phosphatase domain using phosphohistone as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50618392(CHEMBL5405890)
Affinity DataIC50: 700nMAssay Description:Inhibition of PPP5C (unknown origin) phosphatase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50618391(CHEMBL5421006)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PPP5C (unknown origin) phosphatase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein phosphatase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50090503((1R,2S,6R,7S)-4,10-Dioxa-tricyclo[5.2.1.0*2,6*]dec...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PPP5C (unknown origin) phosphatase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50618390(CHEMBL5415208)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of MBP fused recombinant human PPP5C phosphatase domain expressed in Escherichia coli using DiFMUP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMedPDB3D3D Structure (crystal)