Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50019035
TargetMatrix metalloproteinase-14(Human)
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM32188(cid_2788 | TG2-36-2 | CLIOQUINOL | Clioquinol (CQ))
Affinity DataKd:  1.20E+3nMAssay Description:Binding affinity to CMS sensor chip immobilized MMP-14 catalytic domain (unknown origin) assessed as equilibrium dissociation constant by surface pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-14(Human)
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM32147(AS-229 | cid_2722 | CHLOROXINE)
Affinity DataKd:  2.40E+3nMAssay Description:Binding affinity to CMS sensor chip immobilized MMP-14 catalytic domain (unknown origin) assessed as equilibrium dissociation constant by surface pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM32147(AS-229 | cid_2722 | CHLOROXINE)
Affinity DataIC50: 1.59E+4nMAssay Description:Inhibition of MMP-9 (unknown origin) using QXL520-gamma-Abu-Pro-Cha-Abu-Smc-His-Ala-Dab(5-FAM)-Ala-Lys-NH2 as fluorogenic substrate preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCollagenase 3(Human)
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM32147(AS-229 | cid_2722 | CHLOROXINE)
Affinity DataIC50: 1.96E+4nMAssay Description:Inhibition of MMP-13 (unknown origin) using QXL520-gamma-Abu-Pro-Cha-Abu-Smc-His-Ala-Dab(5-FAM)-Ala-Lys-NH2 as fluorogenic substrate preincubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-14(Human)
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM32147(AS-229 | cid_2722 | CHLOROXINE)
Affinity DataIC50: 2.56E+4nMAssay Description:Inhibition of MMP-14 (unknown origin) using 5-FAM-TDVPNGFHVS (QXL520)-NH2 as fluorogenic substrate preincubated for 10 mins followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-14(Human)
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM32188(cid_2788 | TG2-36-2 | CLIOQUINOL | Clioquinol (CQ))
Affinity DataIC50: 2.69E+4nMAssay Description:Inhibition of MMP-14 (unknown origin) using 5-FAM-TDVPNGFHVS (QXL520)-NH2 as fluorogenic substrate preincubated for 10 mins followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-14(Human)
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50614761(CHEMBL5266336)
Affinity DataIC50: 7.12E+4nMAssay Description:Inhibition of MMP-14 (unknown origin) using 5-FAM-TDVPNGFHVS (QXL520)-NH2 as fluorogenic substrate preincubated for 10 mins followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed