Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50019369
TargetNeurotensin receptor type 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50618615(CHEMBL1170627)
Affinity DataKd:  5.70nMAssay Description:Binding affinity to human NTS1R assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNeurotensin receptor type 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50618621(CHEMBL5434985)
Affinity DataEC50:  0.890nMAssay Description:Agonist activity at human NTSR1 expressed in HEK293 cells assessed as Galphaq-mediated modulation of IP production incubated for 90 mins by IP-one HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNeurotensin receptor type 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50618620(CHEMBL5420374)
Affinity DataEC50:  0.740nMAssay Description:Agonist activity at human NTSR1 expressed in HEK293 cells assessed as Galphaq-mediated modulation of IP production incubated for 90 mins by IP-one HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNeurotensin receptor type 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50618619(CHEMBL5409459)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at human NTSR1 expressed in HEK293 cells assessed as Galphaq-mediated modulation of IP production incubated for 90 mins by IP-one HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNeurotensin receptor type 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50618618(CHEMBL5402152)
Affinity DataEC50:  0.850nMAssay Description:Agonist activity at human NTSR1 expressed in HEK293 cells assessed as Galphaq-mediated modulation of IP production incubated for 90 mins by IP-one HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNeurotensin receptor type 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50618617(CHEMBL5441066)
Affinity DataEC50:  0.820nMAssay Description:Agonist activity at human NTSR1 expressed in HEK293 cells assessed as Galphaq-mediated modulation of IP production incubated for 90 mins by IP-one HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNeurotensin receptor type 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50618616(CHEMBL423487)
Affinity DataEC50:  3.20E+3nMAssay Description:Agonist activity at human NTSR1 expressed in HEK293 cells assessed as Galphaq-mediated modulation of IP production incubated for 90 mins by IP-one HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNeurotensin receptor type 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50048908(CHEMBL415788)
Affinity DataEC50:  0.880nMAssay Description:Agonist activity at human NTSR1 expressed in HEK293 cells assessed as Galphaq-mediated modulation of IP production incubated for 90 mins by IP-one HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNeurotensin receptor type 2(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50048908(CHEMBL415788)
Affinity DataKd:  1.80nMAssay Description:Binding affinity to human NTSR2 transfected in HEK293 cells assessed as inhibition constant incubated for 60 mins in the presence of [Leu3H]NT(8-13) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNeurotensin receptor type 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50048908(CHEMBL415788)
Affinity DataKd:  0.680nMAssay Description:Binding affinity to human NTSR1 transfected in HEK293 cells assessed as inhibition constant incubated for 60 mins in the presence of [Leu3H]NT(8-13) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNeurotensin receptor type 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50130880(pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-L...)
Affinity DataKd:  0.400nMAssay Description:Binding affinity to human NTS1R assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNeurotensin receptor type 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50618621(CHEMBL5434985)
Affinity DataKi:  4.20nMAssay Description:Binding affinity to human NTSR1 transfected in HEK293 cells assessed as inhibition constant incubated for 60 mins in the presence of [Leu3H]NT(8-13) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNeurotensin receptor type 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50618620(CHEMBL5420374)
Affinity DataKi:  5.5nMAssay Description:Binding affinity to human NTSR1 transfected in HEK293 cells assessed as inhibition constant incubated for 60 mins in the presence of [Leu3H]NT(8-13) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNeurotensin receptor type 2(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50618620(CHEMBL5420374)
Affinity DataKi:  5.60nMAssay Description:Binding affinity to human NTSR2 transfected in HEK293 cells assessed as inhibition constant incubated for 60 mins in the presence of [Leu3H]NT(8-13) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNeurotensin receptor type 2(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50618621(CHEMBL5434985)
Affinity DataKi:  5.80nMAssay Description:Binding affinity to human NTSR2 transfected in HEK293 cells assessed as inhibition constant incubated for 60 mins in the presence of [Leu3H]NT(8-13) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNeurotensin receptor type 2(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50618617(CHEMBL5441066)
Affinity DataKi:  6.5nMAssay Description:Binding affinity to human NTSR2 transfected in HEK293 cells assessed as inhibition constant incubated for 60 mins in the presence of [Leu3H]NT(8-13) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNeurotensin receptor type 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50618617(CHEMBL5441066)
Affinity DataKi:  6.90nMAssay Description:Binding affinity to human NTSR1 transfected in HEK293 cells assessed as inhibition constant incubated for 60 mins in the presence of [Leu3H]NT(8-13) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNeurotensin receptor type 2(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50618618(CHEMBL5402152)
Affinity DataKi:  14nMAssay Description:Binding affinity to human NTSR2 transfected in HEK293 cells assessed as inhibition constant incubated for 60 mins in the presence of [Leu3H]NT(8-13) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNeurotensin receptor type 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50618618(CHEMBL5402152)
Affinity DataKi:  15nMAssay Description:Binding affinity to human NTSR1 transfected in HEK293 cells assessed as inhibition constant incubated for 60 mins in the presence of [Leu3H]NT(8-13) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNeurotensin receptor type 2(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50618619(CHEMBL5409459)
Affinity DataKi:  54nMAssay Description:Binding affinity to human NTSR2 transfected in HEK293 cells assessed as inhibition constant incubated for 60 mins in the presence of [Leu3H]NT(8-13) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNeurotensin receptor type 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50618619(CHEMBL5409459)
Affinity DataKi:  60nMAssay Description:Binding affinity to human NTSR1 transfected in HEK293 cells assessed as inhibition constant incubated for 60 mins in the presence of [Leu3H]NT(8-13) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNeurotensin receptor type 2(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50618616(CHEMBL423487)
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity to human NTSR2 transfected in HEK293 cells assessed as inhibition constant incubated for 60 mins in the presence of [Leu3H]NT(8-13) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNeurotensin receptor type 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50618616(CHEMBL423487)
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity to human NTSR1 transfected in HEK293 cells assessed as inhibition constant incubated for 60 mins in the presence of [Leu3H]NT(8-13) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed