Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50019691
TargetMelanocortin receptor 3(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50034922((S)-2-{(R)-2-[(S)-2-Acetylamino-3-(1H-imidazol-4-y...)
Affinity DataEC50:  7.10nMAssay Description:Agonist activity at human MC3R stably overexpressing in HEK293 cells assessed as intracellular acumulation of cAMP level incubated for 30 mins measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocortin receptor 5(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50621839(CHEMBL5404193)
Affinity DataEC50:  6nMAssay Description:Agonist activity at human MC5R stably overexpressing in HEK293 cells assessed as intracellular acumulation of cAMP level incubated for 30 mins measur...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocortin receptor 5(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50034922((S)-2-{(R)-2-[(S)-2-Acetylamino-3-(1H-imidazol-4-y...)
Affinity DataEC50:  3.90nMAssay Description:Agonist activity at human MC5R stably overexpressing in HEK293 cells assessed as intracellular acumulation of cAMP level incubated for 30 mins measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocortin receptor 5(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50621836(CHEMBL5423711)
Affinity DataEC50:  165nMAssay Description:Agonist activity at human MC5R stably overexpressing in HEK293 cells assessed as intracellular acumulation of cAMP level incubated for 30 mins measur...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocortin receptor 4(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50621839(CHEMBL5404193)
Affinity DataEC50:  2nMAssay Description:Agonist activity at human MC4R stably overexpressing in HEK293 cells assessed as intracellular acumulation of cAMP level incubated for 30 mins measur...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocortin receptor 4(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50034922((S)-2-{(R)-2-[(S)-2-Acetylamino-3-(1H-imidazol-4-y...)
Affinity DataEC50:  548nMAssay Description:Agonist activity at human MC4R stably overexpressing in HEK293 cells assessed as intracellular acumulation of cAMP level incubated for 30 mins measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocortin receptor 4(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50621837(CHEMBL5395890)
Affinity DataEC50:  4.10nMAssay Description:Agonist activity at human MC4R stably overexpressing in HEK293 cells assessed as intracellular acumulation of cAMP level incubated for 30 mins measur...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocortin receptor 4(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50621840(CHEMBL5418762)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human MC4R stably overexpressing in HEK293 cells assessed as intracellular acumulation of cAMP level incubated for 30 mins measur...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocortin receptor 4(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50621836(CHEMBL5423711)
Affinity DataEC50:  171nMAssay Description:Agonist activity at human MC4R stably overexpressing in HEK293 cells assessed as intracellular acumulation of cAMP level incubated for 30 mins measur...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocortin receptor 3(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50621839(CHEMBL5404193)
Affinity DataEC50:  5.10nMAssay Description:Agonist activity at human MC3R stably overexpressing in HEK293 cells assessed as intracellular acumulation of cAMP level incubated for 30 mins measur...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocortin receptor 3(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50621838(CHEMBL5410873)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human MC3R stably overexpressing in HEK293 cells assessed as intracellular acumulation of cAMP level incubated for 30 mins measur...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocortin receptor 3(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50621840(CHEMBL5418762)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human MC3R stably overexpressing in HEK293 cells assessed as intracellular acumulation of cAMP level incubated for 30 mins measur...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocortin receptor 3(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50621836(CHEMBL5423711)
Affinity DataEC50:  166nMAssay Description:Agonist activity at human MC3R stably overexpressing in HEK293 cells assessed as intracellular acumulation of cAMP level incubated for 30 mins measur...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50621839(CHEMBL5404193)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human MC1R stably overexpressing in HEK293 cells assessed as intracellular acumulation of cAMP level incubated for 30 mins measur...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50621838(CHEMBL5410873)
Affinity DataEC50:  136nMAssay Description:Agonist activity at human MC1R stably overexpressing in HEK293 cells assessed as intracellular acumulation of cAMP level incubated for 30 mins measur...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50621837(CHEMBL5395890)
Affinity DataEC50:  37nMAssay Description:Agonist activity at human MC1R stably overexpressing in HEK293 cells assessed as intracellular acumulation of cAMP level incubated for 30 mins measur...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50621840(CHEMBL5418762)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human MC1R stably overexpressing in HEK293 cells assessed as intracellular acumulation of cAMP level incubated for 30 mins measur...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50621836(CHEMBL5423711)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human MC1R stably overexpressing in HEK293 cells assessed as intracellular acumulation of cAMP level incubated for 30 mins measur...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50034922((S)-2-{(R)-2-[(S)-2-Acetylamino-3-(1H-imidazol-4-y...)
Affinity DataEC50:  4.30nMAssay Description:Agonist activity at human MC1R stably overexpressing in HEK293 cells assessed as intracellular acumulation of cAMP level incubated for 30 mins measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50621839(CHEMBL5404193)
Affinity DataIC50: 1nMAssay Description:Displacement of [I125] NDP-alpha-MSH from human MC1R stably overexpressing in HEK293 cells in presence of [I125] labeled NDP-alpha-MSH treated for 40...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocortin receptor 3(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50621839(CHEMBL5404193)
Affinity DataIC50: 2nMAssay Description:Displacement of [I125] NDP-alpha-MSH from human MC3R stably overexpressing in HEK293 cells in presence of [I125] labeled NDP-alpha-MSH treated for 40...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocortin receptor 4(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50621839(CHEMBL5404193)
Affinity DataIC50: 2.30nMAssay Description:Displacement of [I125] NDP-alpha-MSH from human MC4R stably overexpressing in HEK293 cells in presence of [I125] labeled NDP-alpha-MSH treated for 40...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocortin receptor 4(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50621837(CHEMBL5395890)
Affinity DataIC50: 2.5nMAssay Description:Displacement of [I125] NDP-alpha-MSH from human MC4R stably overexpressing in HEK293 cells in presence of [I125] labeled NDP-alpha-MSH treated for 40...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocortin receptor 5(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50621839(CHEMBL5404193)
Affinity DataIC50: 4nMAssay Description:Displacement of [I125] NDP-alpha-MSH from human MC5R stably overexpressing in HEK293 cells in presence of [I125] labeled NDP-alpha-MSH treated for 40...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50621838(CHEMBL5410873)
Affinity DataIC50: 9.60nMAssay Description:Displacement of [I125] NDP-alpha-MSH from human MC1R stably overexpressing in HEK293 cells in presence of [I125] labeled NDP-alpha-MSH treated for 40...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50621836(CHEMBL5423711)
Affinity DataIC50: 34nMAssay Description:Displacement of [I125] NDP-alpha-MSH from human MC1R stably overexpressing in HEK293 cells in presence of [I125] labeled NDP-alpha-MSH treated for 40...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocortin receptor 5(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50621837(CHEMBL5395890)
Affinity DataIC50: 40nMAssay Description:Displacement of [I125] NDP-alpha-MSH from human MC5R stably overexpressing in HEK293 cells in presence of [I125] labeled NDP-alpha-MSH treated for 40...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocortin receptor 3(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50034922((S)-2-{(R)-2-[(S)-2-Acetylamino-3-(1H-imidazol-4-y...)
Affinity DataIC50: 63nMAssay Description:Displacement of [I125] NDP-alpha-MSH from human MC3R stably overexpressing in HEK293 cells in presence of [I125] labeled NDP-alpha-MSH treated for 40...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50621837(CHEMBL5395890)
Affinity DataIC50: 81nMAssay Description:Displacement of [I125] NDP-alpha-MSH from human MC1R stably overexpressing in HEK293 cells in presence of [I125] labeled NDP-alpha-MSH treated for 40...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50034922((S)-2-{(R)-2-[(S)-2-Acetylamino-3-(1H-imidazol-4-y...)
Affinity DataIC50: 105nMAssay Description:Displacement of [I125] NDP-alpha-MSH from human MC1R stably overexpressing in HEK293 cells in presence of [I125] labeled NDP-alpha-MSH treated for 40...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocortin receptor 5(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50034922((S)-2-{(R)-2-[(S)-2-Acetylamino-3-(1H-imidazol-4-y...)
Affinity DataIC50: 109nMAssay Description:Displacement of [I125] NDP-alpha-MSH from human MC5R stably overexpressing in HEK293 cells in presence of [I125] labeled NDP-alpha-MSH treated for 40...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocortin receptor 3(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50621836(CHEMBL5423711)
Affinity DataIC50: 165nMAssay Description:Displacement of [I125] NDP-alpha-MSH from human MC3R stably overexpressing in HEK293 cells in presence of [I125] labeled NDP-alpha-MSH treated for 40...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocortin receptor 4(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50621836(CHEMBL5423711)
Affinity DataIC50: 166nMAssay Description:Displacement of [I125] NDP-alpha-MSH from human MC4R stably overexpressing in HEK293 cells in presence of [I125] labeled NDP-alpha-MSH treated for 40...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocortin receptor 4(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50034922((S)-2-{(R)-2-[(S)-2-Acetylamino-3-(1H-imidazol-4-y...)
Affinity DataIC50: 359nMAssay Description:Displacement of [I125] NDP-alpha-MSH from human MC4R stably overexpressing in HEK293 cells in presence of [I125] labeled NDP-alpha-MSH treated for 40...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocortin receptor 5(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50621836(CHEMBL5423711)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [I125] NDP-alpha-MSH from human MC5R stably overexpressing in HEK293 cells in presence of [I125] labeled NDP-alpha-MSH treated for 40...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocortin receptor 3(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50621837(CHEMBL5395890)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [I125] NDP-alpha-MSH from human MC3R stably overexpressing in HEK293 cells in presence of [I125] labeled NDP-alpha-MSH treated for 40...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocortin receptor 5(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50621838(CHEMBL5410873)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [I125] NDP-alpha-MSH from human MC5R stably overexpressing in HEK293 cells in presence of [I125] labeled NDP-alpha-MSH treated for 40...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed