Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50020404
Target5-hydroxytryptamine receptor 2C(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50629673(CHEMBL1989287)
Affinity DataIC50: 149nMAssay Description:Inhibition of human 5-HT2C stably transfected in HEK293T cells measured after 1 hrs by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50629673(CHEMBL1989287)
Affinity DataIC50: 564nMAssay Description:Inhibition of human 5-HT2A stably transfected in HEK293T cells measured after 1 hrs by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50629674(Dehydrodicentrine | DEHYDRODICENTRINE)
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of Electrophorus electricus AChE using ATCI as substrate pre-incubated for 10 mins followed by substrate addition measured after 5 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50366292(Dehydroroemerine)
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of Electrophorus electricus AChE using ATCI as substrate pre-incubated for 10 mins followed by substrate addition measured after 5 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50629673(CHEMBL1989287)
Affinity DataIC50: 1.69E+3nMAssay Description:Inhibition of human 5-HT2B stably transfected in HEK293T cells measured after 1 hrs by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50306886(Roemerine-HBr | CHEMBL602275)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of equine serum BuChE using BTCI as substrate pre-incubated for 10 mins followed by substrate addition measured after 5 mins by microplate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50306887(Stephanine | CHEMBL601020)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of equine serum BuChE using BTCI as substrate pre-incubated for 10 mins followed by substrate addition measured after 5 mins by microplate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50629676(CHEMBL5440844)
Affinity DataIC50: 2.85E+3nMAssay Description:Inhibition of Electrophorus electricus AChE using ATCI as substrate pre-incubated for 10 mins followed by substrate addition measured after 5 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50629676(CHEMBL5440844)
Affinity DataIC50: 3.26E+3nMAssay Description:Inhibition of equine serum BuChE using BTCI as substrate pre-incubated for 10 mins followed by substrate addition measured after 5 mins by microplate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50366292(Dehydroroemerine)
Affinity DataIC50: 3.34E+3nMAssay Description:Inhibition of equine serum BuChE using BTCI as substrate pre-incubated for 10 mins followed by substrate addition measured after 5 mins by microplate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50629679(CHEMBL5398483)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of Electrophorus electricus AChE using ATCI as substrate pre-incubated for 10 mins followed by substrate addition measured after 5 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50629674(Dehydrodicentrine | DEHYDRODICENTRINE)
Affinity DataIC50: 5.57E+3nMAssay Description:Inhibition of equine serum BuChE using BTCI as substrate pre-incubated for 10 mins followed by substrate addition measured after 5 mins by microplate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50629678(CHEMBL5430132)
Affinity DataIC50: 5.87E+3nMAssay Description:Inhibition of equine serum BuChE using BTCI as substrate pre-incubated for 10 mins followed by substrate addition measured after 5 mins by microplate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50629672(CHEMBL481631)
Affinity DataIC50: 6.11E+3nMAssay Description:Inhibition of Electrophorus electricus AChE using ATCI as substrate pre-incubated for 10 mins followed by substrate addition measured after 5 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50629678(CHEMBL5430132)
Affinity DataIC50: 6.12E+3nMAssay Description:Inhibition of Electrophorus electricus AChE using ATCI as substrate pre-incubated for 10 mins followed by substrate addition measured after 5 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50629677(CHEMBL1617041)
Affinity DataIC50: 7.42E+3nMAssay Description:Inhibition of equine serum BuChE using BTCI as substrate pre-incubated for 10 mins followed by substrate addition measured after 5 mins by microplate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50306886(Roemerine-HBr | CHEMBL602275)
Affinity DataIC50: 8.32E+3nMAssay Description:Inhibition of Electrophorus electricus AChE using ATCI as substrate pre-incubated for 10 mins followed by substrate addition measured after 5 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50241809((-)-asimilobine | [1-methoxy-5,6,6a,7-tetrahydro-4...)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of equine serum BuChE using BTCI as substrate pre-incubated for 10 mins followed by substrate addition measured after 5 mins by microplate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50629673(CHEMBL1989287)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of Electrophorus electricus AChE using ATCI as substrate pre-incubated for 10 mins followed by substrate addition measured after 5 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50306887(Stephanine | CHEMBL601020)
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of Electrophorus electricus AChE using ATCI as substrate pre-incubated for 10 mins followed by substrate addition measured after 5 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50629680((-)-Isolaureline | CHEMBL510954)
Affinity DataIC50: 1.19E+4nMAssay Description:Inhibition of Electrophorus electricus AChE using ATCI as substrate pre-incubated for 10 mins followed by substrate addition measured after 5 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50629682(CHEMBL5437306)
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of equine serum BuChE using BTCI as substrate pre-incubated for 10 mins followed by substrate addition measured after 5 mins by microplate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50629680((-)-Isolaureline | CHEMBL510954)
Affinity DataIC50: 1.66E+4nMAssay Description:Inhibition of equine serum BuChE using BTCI as substrate pre-incubated for 10 mins followed by substrate addition measured after 5 mins by microplate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50629673(CHEMBL1989287)
Affinity DataIC50: 1.74E+4nMAssay Description:Inhibition of equine serum BuChE using BTCI as substrate pre-incubated for 10 mins followed by substrate addition measured after 5 mins by microplate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50629677(CHEMBL1617041)
Affinity DataIC50: 1.76E+4nMAssay Description:Inhibition of Electrophorus electricus AChE using ATCI as substrate pre-incubated for 10 mins followed by substrate addition measured after 5 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50629675(CHEMBL5433445)
Affinity DataIC50: 2.03E+4nMAssay Description:Inhibition of equine serum BuChE using BTCI as substrate pre-incubated for 10 mins followed by substrate addition measured after 5 mins by microplate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50629679(CHEMBL5398483)
Affinity DataIC50: 2.25E+4nMAssay Description:Inhibition of equine serum BuChE using BTCI as substrate pre-incubated for 10 mins followed by substrate addition measured after 5 mins by microplate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50629672(CHEMBL481631)
Affinity DataIC50: 2.64E+4nMAssay Description:Inhibition of equine serum BuChE using BTCI as substrate pre-incubated for 10 mins followed by substrate addition measured after 5 mins by microplate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50629682(CHEMBL5437306)
Affinity DataIC50: 3.25E+4nMAssay Description:Inhibition of Electrophorus electricus AChE using ATCI as substrate pre-incubated for 10 mins followed by substrate addition measured after 5 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50629681(CHEMBL5414111)
Affinity DataIC50: 3.98E+4nMAssay Description:Inhibition of Electrophorus electricus AChE using ATCI as substrate pre-incubated for 10 mins followed by substrate addition measured after 5 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50629681(CHEMBL5414111)
Affinity DataIC50: 1.04E+5nMAssay Description:Inhibition of equine serum BuChE using BTCI as substrate pre-incubated for 10 mins followed by substrate addition measured after 5 mins by microplate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProlyl endopeptidase(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50250422(N-methyllaurotetanine | (+)-N-methyl-laurotetanine...)
Affinity DataIC50: 1.35E+5nMAssay Description:Inhibition of POP (unknown origin) using ZGP-AMC as substrate pre treated for 5 mins followed by substrate addition measured after 30 mins by ELISA a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50241809((-)-asimilobine | [1-methoxy-5,6,6a,7-tetrahydro-4...)
Affinity DataIC50: 1.41E+5nMAssay Description:Inhibition of Electrophorus electricus AChE using ATCI as substrate pre-incubated for 10 mins followed by substrate addition measured after 5 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProlyl endopeptidase(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50203126(Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...)
Affinity DataIC50: 1.42E+5nMAssay Description:Inhibition of POP (unknown origin) using ZGP-AMC as substrate pre treated for 5 mins followed by substrate addition measured after 30 mins by ELISA a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50629675(CHEMBL5433445)
Affinity DataIC50: 1.47E+5nMAssay Description:Inhibition of Electrophorus electricus AChE using ATCI as substrate pre-incubated for 10 mins followed by substrate addition measured after 5 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50052869(6-Methyl-11-phenyl-5,6,6a,7-tetrahydro-4H-dibenzo[...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50098549((6aR,aS)-3-Methyl-2-(6-methyl-5,6,6a,7-tetrahydro-...)
Affinity DataKi:  3.80nMAssay Description:Displacement of [3H]5-HT from rat 5-HT7 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50087036(6-Methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]ac...)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]5-HT from rat 5-HT7 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50087031(1,6-Dimethyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mn...)
Affinity DataKi:  6.90nMAssay Description:Displacement of [3H]5-HT from rat 5-HT7 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50052869(6-Methyl-11-phenyl-5,6,6a,7-tetrahydro-4H-dibenzo[...)
Affinity DataKi:  9.80nMAssay Description:Displacement of [3H]5-HT from rat 5-HT7 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50098546((R)-11-(2,6-Dimethoxy-phenyl)-6-methyl-5,6,6a,7-te...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]5-HT from rat 5-HT7 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50087036(6-Methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]ac...)
Affinity DataKi:  41nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50087031(1,6-Dimethyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mn...)
Affinity DataKi:  62nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50098549((6aR,aS)-3-Methyl-2-(6-methyl-5,6,6a,7-tetrahydro-...)
Affinity DataKi:  142nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50098546((R)-11-(2,6-Dimethoxy-phenyl)-6-methyl-5,6,6a,7-te...)
Affinity DataKi:  554nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed